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1867-2450812016MarBiophysical reviewsBiophys RevGlucose transporters: physiological and pathological roles.595-910.1007/s12551-015-0186-2Glucose is a primary energy source for most cells and an important substrate for many biochemical reactions. As glucose is a need of each and every cell of the body, so are the glucose transporters. Consequently, all cells express these important proteins on their surface. In recent years developments in genetics have shed new light on the types and physiology of various glucose transporters, of which there are two main types-sodium-glucose linked transporters (SGLTs) and facilitated diffusion glucose transporters (GLUT)-which can be divided into many more subclasses. Transporters differ in terms of their substrate specificity, distribution and regulatory mechanisms. Glucose transporters have also received much attention as therapeutic targets for various diseases. In this review, we attempt to present a simplified view of this complex topic which may be of interest to researchers involved in biochemical and pharmacological research.NavaleArchana MAMDepartment of Pharmacology, Faculty of Pharmacy, Parul University, P.O. Limda, Waghodia Taluka, Vadodara District, 391760, Gujarat, India. archanachavan_83@yahoo.co.in.ParanjapeArchana NANEdutech Learning Solutions Pvt. Ltd., Vadodara, Gujarat, India.engJournal ArticleReview20160119
GermanyBiophys Rev1014985731867-2450Anti-cancer agentsAnti-diabetic agentsGLUTGlucose transportersSGLTCONFLICTS OF INTEREST: Archana M. Navale declares that she has no conflict of interest. Archana N. Paranjape declares that she has no conflict of interest. ETHICAL APPROVAL: This article does not contain any studies with human participants or animals performed by any of the authors.201559201512120175176020163100201631012016119ppublish28510148PMC542573610.1007/s12551-015-0186-210.1007/s12551-015-0186-2Asano T, Katagiri H, Takata K, Lin JL, Ishihara H, Inukai K et al (1991) The role of N-glycosylation of GLUT1 for glucose transport activity. J Biol Chem 266:24632–246361761560Banerjee SK, McGaffin KR, Pastor-Soler NM, Ahmad F. SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states. Cardiovasc Res. 2009;84:111–118. doi: 10.1093/cvr/cvp190.10.1093/cvr/cvp190PMC274134819509029Bryant NJ, Govers R, James DE. Regulated transport of the glucose transporter GLUT4. 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