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<PubmedArticle><MedlineCitation Status="MEDLINE" Owner="NLM" IndexingMethod="Automated"><PMID Version="1">39789386</PMID><DateCompleted><Year>2026</Year><Month>05</Month><Day>11</Day></DateCompleted><DateRevised><Year>2026</Year><Month>05</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-7558</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>2</Issue><PubDate><Year>2026</Year><Month>Apr</Month></PubDate></JournalIssue><Title>International journal of behavioral medicine</Title><ISOAbbreviation>Int J Behav Med</ISOAbbreviation></Journal><ArticleTitle>Stress Appraisal, Stress Mindset, and Perceived Pain During a Cold Pressor Test.</ArticleTitle><Pagination><StartPage>219</StartPage><EndPage>227</EndPage><MedlinePgn>219-227</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s12529-024-10346-7</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Previous studies demonstrated that task-specific stress appraisals as well as the more general belief that stress is (mal)adaptive (i.e., stress mindset) can affect the stress response. Little is known about the influence of stress appraisals and stress mindset on pain perception. The current study investigated whether stress appraisals and/or stress mindset moderates the impact of stress on pain perception.</AbstractText><AbstractText Label="METHOD" NlmCategory="METHODS">Sixty participants performed a stress-inducing speech preparation task followed by the cold pressor test (CPT) to induce pain. Threat appraisal of the speech task was measured with a questionnaire. Stress mindset was manipulated with a video clip emphasizing either the debilitating or enhancing nature of stress, after which another administration of the CPT took place.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Participants in the "stress-is-enhancing" condition reported less pain on the second CPT than on the first, while participants in the "stress-is-debilitating" condition demonstrated similar pain levels. There was no effect of threat appraisals of the speech task on pain perception.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These findings provide evidence on the impact of stress mindset on pain perception. Future studies could extend these findings to patients with pain and examine whether mindset interventions can be a useful component in pain management.</AbstractText><CopyrightInformation>&#xa9; 2025. The Author(s).</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tse</LastName><ForeName>Helen Wing Yuk</ForeName><Initials>HWY</Initials><Identifier Source="ORCID">0000-0002-9677-7652</Identifier><AffiliationInfo><Affiliation>Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanssen</LastName><ForeName>Marjolein M</ForeName><Initials>MM</Initials><Identifier Source="ORCID">0000-0001-7355-9735</Identifier><AffiliationInfo><Affiliation>Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vancleef</LastName><ForeName>Linda M G</ForeName><Initials>LMG</Initials><Identifier Source="ORCID">0000-0002-8566-8696</Identifier><AffiliationInfo><Affiliation>Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Madelon L</ForeName><Initials>ML</Initials><Identifier Source="ORCID">0000-0003-2969-6286</Identifier><AffiliationInfo><Affiliation>Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands. madelon.peters@maastrichtuniversity.nl.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2025</Year><Month>01</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Int J Behav Med</MedlineTA><NlmUniqueID>9421097</NlmUniqueID><ISSNLinking>1070-5503</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058748" MajorTopicYN="Y">Pain Perception</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013315" MajorTopicYN="Y">Stress, Psychological</DescriptorName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003080" MajorTopicYN="N">Cold Temperature</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010147" MajorTopicYN="N">Pain Measurement</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010146" MajorTopicYN="Y">Pain</DescriptorName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000223" MajorTopicYN="Y">Adaptation, Psychological</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cold pressor test</Keyword><Keyword MajorTopicYN="N">Mindset manipulation</Keyword><Keyword MajorTopicYN="N">Speech preparation task</Keyword><Keyword MajorTopicYN="N">Stress appraisal</Keyword><Keyword MajorTopicYN="N">Stress mindset</Keyword></KeywordList><CoiStatement>Declaration. Ethical Approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed Consent: Informed consent was obtained from all individual participants included in the study. Conflict of Interest: The authors declare no competing interests.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2024</Year><Month>12</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2026</Year><Month>5</Month><Day>11</Day><Hour>13</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2025</Year><Month>1</Month><Day>10</Day><Hour>0</Hour><Minute>21</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2025</Year><Month>1</Month><Day>9</Day><Hour>23</Hour><Minute>32</Minute></PubMedPubDate><PubMedPubDate PubStatus="pmc-release"><Year>2025</Year><Month>1</Month><Day>9</Day></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">39789386</ArticleId><ArticleId IdType="pmc">PMC13161006</ArticleId><ArticleId IdType="doi">10.1007/s12529-024-10346-7</ArticleId><ArticleId IdType="pii">10.1007/s12529-024-10346-7</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Jennings EM, Okine BN, Roche M, Finn DP. 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