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0925-477311312002AprMechanisms of developmentMech DevThe expression of gbx-2 during zebrafish embryogenesis.107110107-10Gbx-2 is a homeobox gene essential for normal development of the midbrain and the anterior hindbrain. Zebrafish gbx-2 shares an overall similarity of 67.8, 68.1, 60.6 and 66.5% in amino acid sequence to human, mouse, chick and Xenopus Gbx-2, respectively. The expression of zebrafish gbx-2 is initially, before the completion of epiboly, restricted to the prospective posterior midbrain. The expression remains detectable until the end of pharyngula period. The gbx-2 mRNA is also detected in the otic vesicles, the dorsoposterior telencephalon, the rostral branchial arches, the pronephric duct and median fin fold.SuYingYProtein Science Laboratory of the MOE, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People's Republic of China.MengAnmingAengGENBANKAF288762Journal ArticleResearch Support, Non-U.S. Gov't
IrelandMech Dev91012180925-47730GBX2 protein, human0Gbx2 protein, Xenopus0Gbx2 protein, mouse0Homeodomain Proteins0RNA, Antisense0RNA, Messenger0Xenopus Proteins0Zebrafish Proteins0gbx2 protein, zebrafishIMAmino Acid SequenceAnimalsBrainembryologyChick EmbryoGene Expression Regulation, DevelopmentalHomeodomain ProteinsbiosynthesisHumansIn Situ HybridizationMiceMolecular Sequence DataRNA, AntisensebiosynthesisRNA, MessengermetabolismSequence Homology, Amino AcidTissue DistributionXenopus ProteinsZebrafishZebrafish Proteins20023201002002109402002320100ppublish1190098410.1016/s0925-4773(02)00011-4S0925477302000114