{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Manual"},"PMID":{"@attributes":{"Version":"1"},"@text":"10896164"},"DateCompleted":{"Year":"2000","Month":"08","Day":"07"},"DateRevised":{"Year":"2022","Month":"03","Day":"09"},"Article":{"@attributes":{"PubModel":"Print"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Print"},"@text":"0896-6273"},"JournalIssue":{"@attributes":{"CitedMedium":"Print"},"Volume":"26","Issue":"3","PubDate":{"Year":"2000","Month":"Jun"}},"Title":"Neuron","ISOAbbreviation":"Neuron"},"ArticleTitle":"Adaptive rescaling maximizes information transmission.","Pagination":{"StartPage":"695","EndPage":"702","MedlinePgn":"695-702"},"Abstract":{"AbstractText":["Adaptation is a widespread phenomenon in nervous systems, providing flexibility to function under varying external conditions. Here, we relate an adaptive property of a sensory system directly to its function as a carrier of information about input signals. We show that the input\/output relation of a sensory system in a dynamic environment changes with the statistical properties of the environment. Specifically, when the dynamic range of inputs changes, the input\/output relation rescales so as to match the dynamic range of responses to that of the inputs. We give direct evidence that the scaling of the input\/output relation is set to maximize information transmission for each distribution of signals. This adaptive behavior should be particularly useful in dealing with the intermittent statistics of natural signals."]},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Brenner","ForeName":"N","Initials":"N","AffiliationInfo":[{"Affiliation":"NEC Research Institute, Princeton, New Jersey 08540, USA."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Bialek","ForeName":"W","Initials":"W"},{"@attributes":{"ValidYN":"Y"},"LastName":"de Ruyter van Steveninck","ForeName":"R","Initials":"R"}]},"Language":["eng"],"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D016428"},"@text":"Journal Article"}]}},"MedlineJournalInfo":{"Country":"United States","MedlineTA":"Neuron","NlmUniqueID":"8809320","ISSNLinking":"0896-6273"},"CitationSubset":["IM"],"CommentsCorrectionsList":{"CommentsCorrections":[{"@attributes":{"RefType":"CommentIn"},"RefSource":"Neuron. 2000 Jun;26(3):546-8. doi: 10.1016\/s0896-6273(00)81188-5.","PMID":{"@attributes":{"Version":"1"},"@text":"10896148"}}]},"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D000222","MajorTopicYN":"N"},"@text":"Adaptation, Physiological"},"QualifierName":[{"@attributes":{"UI":"Q000502","MajorTopicYN":"Y"},"@text":"physiology"}]},{"DescriptorName":{"@attributes":{"UI":"D000818","MajorTopicYN":"N"},"@text":"Animals"}},{"DescriptorName":{"@attributes":{"UI":"D004175","MajorTopicYN":"N"},"@text":"Diptera"}},{"DescriptorName":{"@attributes":{"UI":"D004777","MajorTopicYN":"N"},"@text":"Environment"}},{"DescriptorName":{"@attributes":{"UI":"D005260","MajorTopicYN":"N"},"@text":"Female"}},{"DescriptorName":{"@attributes":{"UI":"D009475","MajorTopicYN":"N"},"@text":"Neurons, Afferent"},"QualifierName":[{"@attributes":{"UI":"Q000502","MajorTopicYN":"N"},"@text":"physiology"}]},{"DescriptorName":{"@attributes":{"UI":"D012677","MajorTopicYN":"N"},"@text":"Sensation"},"QualifierName":[{"@attributes":{"UI":"Q000502","MajorTopicYN":"Y"},"@text":"physiology"}]},{"DescriptorName":{"@attributes":{"UI":"D009435","MajorTopicYN":"N"},"@text":"Synaptic Transmission"},"QualifierName":[{"@attributes":{"UI":"Q000502","MajorTopicYN":"Y"},"@text":"physiology"}]}]}},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"pubmed"},"Year":"2000","Month":"7","Day":"15","Hour":"11","Minute":"0"},{"@attributes":{"PubStatus":"medline"},"Year":"2000","Month":"8","Day":"12","Hour":"11","Minute":"0"},{"@attributes":{"PubStatus":"entrez"},"Year":"2000","Month":"7","Day":"15","Hour":"11","Minute":"0"}]},"PublicationStatus":"ppublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"10896164"},{"@attributes":{"IdType":"doi"},"@text":"10.1016\/s0896-6273(00)81205-2"},{"@attributes":{"IdType":"pii"},"@text":"S0896-6273(00)81205-2"}]}}}}