{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Manual"},"PMID":{"@attributes":{"Version":"1"},"@text":"11900984"},"DateCompleted":{"Year":"2002","Month":"10","Day":"08"},"DateRevised":{"Year":"2019","Month":"09","Day":"10"},"Article":{"@attributes":{"PubModel":"Print"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Print"},"@text":"0925-4773"},"JournalIssue":{"@attributes":{"CitedMedium":"Print"},"Volume":"113","Issue":"1","PubDate":{"Year":"2002","Month":"Apr"}},"Title":"Mechanisms of development","ISOAbbreviation":"Mech Dev"},"ArticleTitle":"The expression of gbx-2 during zebrafish embryogenesis.","Pagination":{"StartPage":"107","EndPage":"110","MedlinePgn":"107-10"},"Abstract":{"AbstractText":["Gbx-2 is a homeobox gene essential for normal development of the midbrain and the anterior hindbrain. Zebrafish gbx-2 shares an overall similarity of 67.8, 68.1, 60.6 and 66.5% in amino acid sequence to human, mouse, chick and Xenopus Gbx-2, respectively. The expression of zebrafish gbx-2 is initially, before the completion of epiboly, restricted to the prospective posterior midbrain. The expression remains detectable until the end of pharyngula period. The gbx-2 mRNA is also detected in the otic vesicles, the dorsoposterior telencephalon, the rostral branchial arches, the pronephric duct and median fin fold."]},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Su","ForeName":"Ying","Initials":"Y","AffiliationInfo":[{"Affiliation":"Protein Science Laboratory of the MOE, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People's Republic of China."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Meng","ForeName":"Anming","Initials":"A"}]},"Language":["eng"],"DataBankList":{"@attributes":{"CompleteYN":"Y"},"DataBank":[{"DataBankName":"GENBANK","AccessionNumberList":{"AccessionNumber":["AF288762"]}}]},"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D016428"},"@text":"Journal Article"},{"@attributes":{"UI":"D013485"},"@text":"Research Support, Non-U.S. Gov't"}]}},"MedlineJournalInfo":{"Country":"Ireland","MedlineTA":"Mech Dev","NlmUniqueID":"9101218","ISSNLinking":"0925-4773"},"ChemicalList":{"Chemical":[{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"C084958"},"@text":"GBX2 protein, human"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"C513180"},"@text":"Gbx2 protein, Xenopus"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"C513182"},"@text":"Gbx2 protein, mouse"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D018398"},"@text":"Homeodomain Proteins"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D016372"},"@text":"RNA, Antisense"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D012333"},"@text":"RNA, Messenger"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D029867"},"@text":"Xenopus Proteins"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D029961"},"@text":"Zebrafish Proteins"}},{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"C513181"},"@text":"gbx2 protein, zebrafish"}}]},"CitationSubset":["IM"],"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D000595","MajorTopicYN":"N"},"@text":"Amino Acid Sequence"}},{"DescriptorName":{"@attributes":{"UI":"D000818","MajorTopicYN":"N"},"@text":"Animals"}},{"DescriptorName":{"@attributes":{"UI":"D001921","MajorTopicYN":"N"},"@text":"Brain"},"QualifierName":[{"@attributes":{"UI":"Q000196","MajorTopicYN":"Y"},"@text":"embryology"}]},{"DescriptorName":{"@attributes":{"UI":"D002642","MajorTopicYN":"N"},"@text":"Chick Embryo"}},{"DescriptorName":{"@attributes":{"UI":"D018507","MajorTopicYN":"Y"},"@text":"Gene Expression Regulation, Developmental"}},{"DescriptorName":{"@attributes":{"UI":"D018398","MajorTopicYN":"N"},"@text":"Homeodomain Proteins"},"QualifierName":[{"@attributes":{"UI":"Q000096","MajorTopicYN":"Y"},"@text":"biosynthesis"}]},{"DescriptorName":{"@attributes":{"UI":"D006801","MajorTopicYN":"N"},"@text":"Humans"}},{"DescriptorName":{"@attributes":{"UI":"D017403","MajorTopicYN":"N"},"@text":"In Situ Hybridization"}},{"DescriptorName":{"@attributes":{"UI":"D051379","MajorTopicYN":"N"},"@text":"Mice"}},{"DescriptorName":{"@attributes":{"UI":"D008969","MajorTopicYN":"N"},"@text":"Molecular Sequence Data"}},{"DescriptorName":{"@attributes":{"UI":"D016372","MajorTopicYN":"N"},"@text":"RNA, Antisense"},"QualifierName":[{"@attributes":{"UI":"Q000096","MajorTopicYN":"N"},"@text":"biosynthesis"}]},{"DescriptorName":{"@attributes":{"UI":"D012333","MajorTopicYN":"N"},"@text":"RNA, Messenger"},"QualifierName":[{"@attributes":{"UI":"Q000378","MajorTopicYN":"N"},"@text":"metabolism"}]},{"DescriptorName":{"@attributes":{"UI":"D017386","MajorTopicYN":"N"},"@text":"Sequence Homology, Amino Acid"}},{"DescriptorName":{"@attributes":{"UI":"D014018","MajorTopicYN":"N"},"@text":"Tissue Distribution"}},{"DescriptorName":{"@attributes":{"UI":"D029867","MajorTopicYN":"N"},"@text":"Xenopus Proteins"}},{"DescriptorName":{"@attributes":{"UI":"D015027","MajorTopicYN":"N"},"@text":"Zebrafish"}},{"DescriptorName":{"@attributes":{"UI":"D029961","MajorTopicYN":"N"},"@text":"Zebrafish Proteins"}}]}},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"pubmed"},"Year":"2002","Month":"3","Day":"20","Hour":"10","Minute":"0"},{"@attributes":{"PubStatus":"medline"},"Year":"2002","Month":"10","Day":"9","Hour":"4","Minute":"0"},{"@attributes":{"PubStatus":"entrez"},"Year":"2002","Month":"3","Day":"20","Hour":"10","Minute":"0"}]},"PublicationStatus":"ppublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"11900984"},{"@attributes":{"IdType":"doi"},"@text":"10.1016\/s0925-4773(02)00011-4"},{"@attributes":{"IdType":"pii"},"@text":"S0925477302000114"}]}}}}