{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Automated"},"PMID":{"@attributes":{"Version":"1"},"@text":"35839922"},"DateCompleted":{"Year":"2022","Month":"12","Day":"06"},"DateRevised":{"Year":"2025","Month":"06","Day":"23"},"Article":{"@attributes":{"PubModel":"Print-Electronic"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Electronic"},"@text":"1532-821X"},"JournalIssue":{"@attributes":{"CitedMedium":"Internet"},"Volume":"103","Issue":"12","PubDate":{"Year":"2022","Month":"Dec"}},"Title":"Archives of physical medicine and rehabilitation","ISOAbbreviation":"Arch Phys Med Rehabil"},"ArticleTitle":"Prevalence of Neuropsychiatric Disorders in Duchenne and Becker Muscular Dystrophies: A Systematic Review and Meta-analysis.","Pagination":{"StartPage":"2444","EndPage":"2453","MedlinePgn":"2444-2453"},"ELocationID":[{"@attributes":{"EIdType":"doi","ValidYN":"Y"},"@text":"10.1016\/j.apmr.2022.05.015"},{"@attributes":{"EIdType":"pii","ValidYN":"Y"},"@text":"S0003-9993(22)00472-5"}],"Abstract":{"AbstractText":[{"@attributes":{"Label":"OBJECTIVE"},"@text":"To estimate the prevalence of neuropsychiatric disorders, including autism spectrum disorders (ASDs), attention-deficit hyperactivity disorder (ADHD), depression, anxiety disorders, and obsessive-compulsive disorder (OCD), in populations with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD)."},{"@attributes":{"Label":"DATA SOURCES"},"@text":"MEDLINE (via PubMed), Scopus, Web of Science, and Cochrane Library from inception to November 2021."},{"@attributes":{"Label":"STUDY SELECTION"},"@text":"Observational studies of individuals with DMD or BMD that estimated the prevalence of ASDs, ADHD, depression, anxiety disorders, and OCD in each population."},{"@attributes":{"Label":"DATA EXTRACTION"},"@text":"A random-effects meta-analysis was performed on each outcome and each population (ie, DMD, BMD)."},{"@attributes":{"Label":"DATA SYNTHESIS"},"@text":"Twenty-three studies were included in the meta-analysis. In DMD, there was a prevalence of 7.0% of ASDs, 18.0% of ADHD, 11.0% of depression, 24.0% of anxiety disorders, and 12.0% of OCD. Furthermore, in BMD, there was a prevalence of 6.0% of ASDs, 28.0% of ADHD, 7.0% of depression, 25.0% of anxiety disorders, and 7.0% of OCD."},{"@attributes":{"Label":"CONCLUSIONS"},"@text":"The prevalence of these neuropsychiatric disorders is higher among patients with DMD or BMD than among the general population, and the presence of these disorders may negatively influence optimal medical management."}],"CopyrightInformation":"Copyright \u00a9 2022 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved."},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Pascual-Morena","ForeName":"Carlos","Initials":"C","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Cavero-Redondo","ForeName":"Iv\u00e1n","Initials":"I","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain; Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Chile, Talca, Chile."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Reina-Guti\u00e9rrez","ForeName":"Sara","Initials":"S","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain. Electronic address: sara.reina@uclm.es."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Saz-Lara","ForeName":"Alicia","Initials":"A","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"L\u00f3pez-Gil","ForeName":"Jos\u00e9 Francisco","Initials":"JF","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Mart\u00ednez-Vizca\u00edno","ForeName":"Vicente","Initials":"V","AffiliationInfo":[{"Affiliation":"Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain; Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Chile, Talca, Chile."}]}]},"Language":["eng"],"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D017418"},"@text":"Meta-Analysis"},{"@attributes":{"UI":"D000078182"},"@text":"Systematic Review"},{"@attributes":{"UI":"D016428"},"@text":"Journal Article"},{"@attributes":{"UI":"D013485"},"@text":"Research Support, Non-U.S. Gov't"}]},"ArticleDate":[{"@attributes":{"DateType":"Electronic"},"Year":"2022","Month":"07","Day":"15"}]},"MedlineJournalInfo":{"Country":"United States","MedlineTA":"Arch Phys Med Rehabil","NlmUniqueID":"2985158R","ISSNLinking":"0003-9993"},"CitationSubset":["IM"],"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D006801","MajorTopicYN":"N"},"@text":"Humans"}},{"DescriptorName":{"@attributes":{"UI":"D020388","MajorTopicYN":"Y"},"@text":"Muscular Dystrophy, Duchenne"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"}]},{"DescriptorName":{"@attributes":{"UI":"D015995","MajorTopicYN":"N"},"@text":"Prevalence"}},{"DescriptorName":{"@attributes":{"UI":"D001289","MajorTopicYN":"Y"},"@text":"Attention Deficit Disorder with Hyperactivity"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"}]},{"DescriptorName":{"@attributes":{"UI":"D001008","MajorTopicYN":"N"},"@text":"Anxiety Disorders"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"}]}]},"KeywordList":[{"@attributes":{"Owner":"NOTNLM"},"Keyword":[{"@attributes":{"MajorTopicYN":"N"},"@text":"Anxiety disorders"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Attention deficit disorder with hyperactivity"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Autism spectrum disorder"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Depressive disorder"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Duchenne"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Muscular dystrophies"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Muscular dystrophy"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Neuromuscular diseases"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Obsessivecompulsive disorder"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Rehabilitation"}]}]},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"received"},"Year":"2022","Month":"1","Day":"11"},{"@attributes":{"PubStatus":"revised"},"Year":"2022","Month":"5","Day":"7"},{"@attributes":{"PubStatus":"accepted"},"Year":"2022","Month":"5","Day":"17"},{"@attributes":{"PubStatus":"pubmed"},"Year":"2022","Month":"7","Day":"16","Hour":"6","Minute":"0"},{"@attributes":{"PubStatus":"medline"},"Year":"2022","Month":"12","Day":"7","Hour":"6","Minute":"0"},{"@attributes":{"PubStatus":"entrez"},"Year":"2022","Month":"7","Day":"15","Hour":"19","Minute":"24"}]},"PublicationStatus":"ppublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"35839922"},{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.apmr.2022.05.015"},{"@attributes":{"IdType":"pii"},"@text":"S0003-9993(22)00472-5"}]}}}}