{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Automated"},"PMID":{"@attributes":{"Version":"1"},"@text":"39608472"},"DateCompleted":{"Year":"2025","Month":"01","Day":"08"},"DateRevised":{"Year":"2025","Month":"01","Day":"08"},"Article":{"@attributes":{"PubModel":"Print-Electronic"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Electronic"},"@text":"1532-8511"},"JournalIssue":{"@attributes":{"CitedMedium":"Internet"},"Volume":"34","Issue":"1","PubDate":{"Year":"2025","Month":"Jan"}},"Title":"Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association","ISOAbbreviation":"J Stroke Cerebrovasc Dis"},"ArticleTitle":"Association between leisure-time physical activity and stroke in patients with chronic obstructive pulmonary disease: A population-based study.","Pagination":{"StartPage":"108162","MedlinePgn":"108162"},"ELocationID":[{"@attributes":{"EIdType":"doi","ValidYN":"Y"},"@text":"10.1016\/j.jstrokecerebrovasdis.2024.108162"},{"@attributes":{"EIdType":"pii","ValidYN":"Y"},"@text":"S1052-3057(24)00605-0"}],"Abstract":{"AbstractText":[{"@attributes":{"Label":"BACKGROUND","NlmCategory":"BACKGROUND"},"@text":"Stroke is the second leading cause of death worldwide. It remains unclear whether chronic obstructive pulmonary disease (COPD) increases the risk of stroke. The purpose of this study was to evaluate the association between COPD and stroke. As physical activity may prevent strokes, we examined whether leisure-time physical activity (LTPA) moderates stroke risk in COPD patients."},{"@attributes":{"Label":"METHODS","NlmCategory":"METHODS"},"@text":"13,524 participants from the 2009-2018 National Health and Nutrition Examination Survey (NHANES). We used the Global Physical Activity Questionnaire (GPAQ) questionnaire to obtain self-reported data from LTPA. We used a binary logistic regression model to analyze the association between LTPA, COPD, and stroke risk."},{"@attributes":{"Label":"RESULTS","NlmCategory":"RESULTS"},"@text":"The prevalence of COPD in the present study was 5.54%. The risk of stroke in COPD patients is 1.84 times higher than that in those without COPD, with a 95% confidence interval (95%CI) of 1.32,2.56 and P < 0.001. A lower stroke risk was observed in COPD patients who adhered to LTPA than those who did not (OR, 0.50; 95%CI, 0.26, 0.95; P = 0.03). As shown by the restricted cubic spline (RCS), the duration of LTPA in COPD patients was inversely related to the risk of stroke, which decreased as the duration of weekly LTPA increased."},{"@attributes":{"Label":"CONCLUSION","NlmCategory":"CONCLUSIONS"},"@text":"COPD is positively associated with stroke risk. LTPA reduces the risk of stroke in patients with COPD, suggesting that it may be a promising measure for preventing stroke in this population."}],"CopyrightInformation":"Copyright \u00a9 2024 The Author(s). Published by Elsevier Inc. All rights reserved."},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Wang","ForeName":"Hongping","Initials":"H","AffiliationInfo":[{"Affiliation":"Department of Neurosurgery, Zigong Fourth People's Hospital, 19 Tanmulin Street, Zigong, Sichuan 643000, China. Electronic address: whp1071@163.com."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Tian","ForeName":"Maoliang","Initials":"M","AffiliationInfo":[{"Affiliation":"Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, 42 Shangyihao Yizhi Street, Zigong, Sichuan 643000, China. Electronic address: tml666tml123@163.com."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Lai","ForeName":"Qun","Initials":"Q","AffiliationInfo":[{"Affiliation":"Department of Hematology and Rheumatology, Zigong Fourth People's Hospital, 19 Tanmulin Street, Zigong, Sichuan 643000, China. Electronic address: laiqun1071@163.com."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Li","ForeName":"Wenqiang","Initials":"W","AffiliationInfo":[{"Affiliation":"Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, 42 Shangyihao Yizhi Street, Zigong, Sichuan 643000, China. Electronic address: lwq1858320@163.com."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Ding","ForeName":"Hao","Initials":"H","AffiliationInfo":[{"Affiliation":"Department of Neurosurgery, Zigong Fourth People's Hospital, 19 Tanmulin Street, Zigong, Sichuan 643000, China. Electronic address: dinghaowws@126.com."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Deng","ForeName":"Zhiping","Initials":"Z","AffiliationInfo":[{"Affiliation":"Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, 42 Shangyihao Yizhi Street, Zigong, Sichuan 643000, China. Electronic address: dengzp1016@163.com."}]}]},"Language":["eng"],"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D016428"},"@text":"Journal Article"}]},"ArticleDate":[{"@attributes":{"DateType":"Electronic"},"Year":"2024","Month":"11","Day":"27"}]},"MedlineJournalInfo":{"Country":"United States","MedlineTA":"J Stroke Cerebrovasc Dis","NlmUniqueID":"9111633","ISSNLinking":"1052-3057"},"CitationSubset":["IM"],"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D006801","MajorTopicYN":"N"},"@text":"Humans"}},{"DescriptorName":{"@attributes":{"UI":"D029424","MajorTopicYN":"Y"},"@text":"Pulmonary Disease, Chronic Obstructive"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"},{"@attributes":{"UI":"Q000175","MajorTopicYN":"N"},"@text":"diagnosis"},{"@attributes":{"UI":"Q000503","MajorTopicYN":"N"},"@text":"physiopathology"}]},{"DescriptorName":{"@attributes":{"UI":"D008297","MajorTopicYN":"N"},"@text":"Male"}},{"DescriptorName":{"@attributes":{"UI":"D005260","MajorTopicYN":"N"},"@text":"Female"}},{"DescriptorName":{"@attributes":{"UI":"D008875","MajorTopicYN":"N"},"@text":"Middle Aged"}},{"DescriptorName":{"@attributes":{"UI":"D012307","MajorTopicYN":"N"},"@text":"Risk Factors"}},{"DescriptorName":{"@attributes":{"UI":"D007899","MajorTopicYN":"Y"},"@text":"Leisure Activities"}},{"DescriptorName":{"@attributes":{"UI":"D015444","MajorTopicYN":"Y"},"@text":"Exercise"}},{"DescriptorName":{"@attributes":{"UI":"D020521","MajorTopicYN":"Y"},"@text":"Stroke"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"},{"@attributes":{"UI":"Q000175","MajorTopicYN":"N"},"@text":"diagnosis"},{"@attributes":{"UI":"Q000503","MajorTopicYN":"N"},"@text":"physiopathology"},{"@attributes":{"UI":"Q000517","MajorTopicYN":"N"},"@text":"prevention & control"}]},{"DescriptorName":{"@attributes":{"UI":"D000368","MajorTopicYN":"N"},"@text":"Aged"}},{"DescriptorName":{"@attributes":{"UI":"D015995","MajorTopicYN":"N"},"@text":"Prevalence"}},{"DescriptorName":{"@attributes":{"UI":"D009749","MajorTopicYN":"Y"},"@text":"Nutrition Surveys"}},{"DescriptorName":{"@attributes":{"UI":"D013997","MajorTopicYN":"N"},"@text":"Time Factors"}},{"DescriptorName":{"@attributes":{"UI":"D018570","MajorTopicYN":"N"},"@text":"Risk Assessment"}},{"DescriptorName":{"@attributes":{"UI":"D003430","MajorTopicYN":"N"},"@text":"Cross-Sectional Studies"}},{"DescriptorName":{"@attributes":{"UI":"D065840","MajorTopicYN":"N"},"@text":"Protective Factors"}},{"DescriptorName":{"@attributes":{"UI":"D014481","MajorTopicYN":"N","Type":"Geographic"},"@text":"United States"},"QualifierName":[{"@attributes":{"UI":"Q000453","MajorTopicYN":"N"},"@text":"epidemiology"}]},{"DescriptorName":{"@attributes":{"UI":"D040242","MajorTopicYN":"N"},"@text":"Risk Reduction Behavior"}},{"DescriptorName":{"@attributes":{"UI":"D000328","MajorTopicYN":"N"},"@text":"Adult"}}]},"KeywordList":[{"@attributes":{"Owner":"NOTNLM"},"Keyword":[{"@attributes":{"MajorTopicYN":"N"},"@text":"Chronic obstructive pulmonary disease"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Leisure-time physical activity"},{"@attributes":{"MajorTopicYN":"N"},"@text":"NHANES"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Stroke"}]}],"CoiStatement":"Declaration of competing interest All authors declare that there are no additional disclosures and conflicts of interest to report."},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"received"},"Year":"2024","Month":"3","Day":"6"},{"@attributes":{"PubStatus":"revised"},"Year":"2024","Month":"11","Day":"24"},{"@attributes":{"PubStatus":"accepted"},"Year":"2024","Month":"11","Day":"25"},{"@attributes":{"PubStatus":"medline"},"Year":"2025","Month":"1","Day":"9","Hour":"0","Minute":"22"},{"@attributes":{"PubStatus":"pubmed"},"Year":"2024","Month":"11","Day":"29","Hour":"5","Minute":"20"},{"@attributes":{"PubStatus":"entrez"},"Year":"2024","Month":"11","Day":"28","Hour":"19","Minute":"30"}]},"PublicationStatus":"ppublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"39608472"},{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.jstrokecerebrovasdis.2024.108162"},{"@attributes":{"IdType":"pii"},"@text":"S1052-3057(24)00605-0"}]}}}}