{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Automated"},"PMID":{"@attributes":{"Version":"1"},"@text":"39789386"},"DateCompleted":{"Year":"2026","Month":"05","Day":"11"},"DateRevised":{"Year":"2026","Month":"05","Day":"14"},"Article":{"@attributes":{"PubModel":"Print-Electronic"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Electronic"},"@text":"1532-7558"},"JournalIssue":{"@attributes":{"CitedMedium":"Internet"},"Volume":"33","Issue":"2","PubDate":{"Year":"2026","Month":"Apr"}},"Title":"International journal of behavioral medicine","ISOAbbreviation":"Int J Behav Med"},"ArticleTitle":"Stress Appraisal, Stress Mindset, and Perceived Pain During a Cold Pressor Test.","Pagination":{"StartPage":"219","EndPage":"227","MedlinePgn":"219-227"},"ELocationID":[{"@attributes":{"EIdType":"doi","ValidYN":"Y"},"@text":"10.1007\/s12529-024-10346-7"}],"Abstract":{"AbstractText":[{"@attributes":{"Label":"BACKGROUND","NlmCategory":"BACKGROUND"},"@text":"Previous studies demonstrated that task-specific stress appraisals as well as the more general belief that stress is (mal)adaptive (i.e., stress mindset) can affect the stress response. Little is known about the influence of stress appraisals and stress mindset on pain perception. The current study investigated whether stress appraisals and\/or stress mindset moderates the impact of stress on pain perception."},{"@attributes":{"Label":"METHOD","NlmCategory":"METHODS"},"@text":"Sixty participants performed a stress-inducing speech preparation task followed by the cold pressor test (CPT) to induce pain. Threat appraisal of the speech task was measured with a questionnaire. Stress mindset was manipulated with a video clip emphasizing either the debilitating or enhancing nature of stress, after which another administration of the CPT took place."},{"@attributes":{"Label":"RESULTS","NlmCategory":"RESULTS"},"@text":"Participants in the \"stress-is-enhancing\" condition reported less pain on the second CPT than on the first, while participants in the \"stress-is-debilitating\" condition demonstrated similar pain levels. There was no effect of threat appraisals of the speech task on pain perception."},{"@attributes":{"Label":"CONCLUSION","NlmCategory":"CONCLUSIONS"},"@text":"These findings provide evidence on the impact of stress mindset on pain perception. Future studies could extend these findings to patients with pain and examine whether mindset interventions can be a useful component in pain management."}],"CopyrightInformation":"\u00a9 2025. The Author(s)."},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Tse","ForeName":"Helen Wing Yuk","Initials":"HWY","Identifier":[{"@attributes":{"Source":"ORCID"},"@text":"0000-0002-9677-7652"}],"AffiliationInfo":[{"Affiliation":"Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Hanssen","ForeName":"Marjolein M","Initials":"MM","Identifier":[{"@attributes":{"Source":"ORCID"},"@text":"0000-0001-7355-9735"}],"AffiliationInfo":[{"Affiliation":"Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Vancleef","ForeName":"Linda M G","Initials":"LMG","Identifier":[{"@attributes":{"Source":"ORCID"},"@text":"0000-0002-8566-8696"}],"AffiliationInfo":[{"Affiliation":"Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Peters","ForeName":"Madelon L","Initials":"ML","Identifier":[{"@attributes":{"Source":"ORCID"},"@text":"0000-0003-2969-6286"}],"AffiliationInfo":[{"Affiliation":"Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands. madelon.peters@maastrichtuniversity.nl."}]}]},"Language":["eng"],"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D016428"},"@text":"Journal Article"}]},"ArticleDate":[{"@attributes":{"DateType":"Electronic"},"Year":"2025","Month":"01","Day":"09"}]},"MedlineJournalInfo":{"Country":"England","MedlineTA":"Int J Behav Med","NlmUniqueID":"9421097","ISSNLinking":"1070-5503"},"CitationSubset":["IM"],"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D006801","MajorTopicYN":"N"},"@text":"Humans"}},{"DescriptorName":{"@attributes":{"UI":"D008297","MajorTopicYN":"N"},"@text":"Male"}},{"DescriptorName":{"@attributes":{"UI":"D005260","MajorTopicYN":"N"},"@text":"Female"}},{"DescriptorName":{"@attributes":{"UI":"D058748","MajorTopicYN":"Y"},"@text":"Pain Perception"},"QualifierName":[{"@attributes":{"UI":"Q000502","MajorTopicYN":"N"},"@text":"physiology"}]},{"DescriptorName":{"@attributes":{"UI":"D013315","MajorTopicYN":"Y"},"@text":"Stress, Psychological"},"QualifierName":[{"@attributes":{"UI":"Q000523","MajorTopicYN":"N"},"@text":"psychology"}]},{"DescriptorName":{"@attributes":{"UI":"D003080","MajorTopicYN":"N"},"@text":"Cold Temperature"}},{"DescriptorName":{"@attributes":{"UI":"D000328","MajorTopicYN":"N"},"@text":"Adult"}},{"DescriptorName":{"@attributes":{"UI":"D055815","MajorTopicYN":"N"},"@text":"Young Adult"}},{"DescriptorName":{"@attributes":{"UI":"D010147","MajorTopicYN":"N"},"@text":"Pain Measurement"}},{"DescriptorName":{"@attributes":{"UI":"D010146","MajorTopicYN":"Y"},"@text":"Pain"},"QualifierName":[{"@attributes":{"UI":"Q000523","MajorTopicYN":"N"},"@text":"psychology"}]},{"DescriptorName":{"@attributes":{"UI":"D011795","MajorTopicYN":"N"},"@text":"Surveys and Questionnaires"}},{"DescriptorName":{"@attributes":{"UI":"D000223","MajorTopicYN":"Y"},"@text":"Adaptation, Psychological"}}]},"KeywordList":[{"@attributes":{"Owner":"NOTNLM"},"Keyword":[{"@attributes":{"MajorTopicYN":"N"},"@text":"Cold pressor test"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Mindset manipulation"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Speech preparation task"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Stress appraisal"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Stress mindset"}]}],"CoiStatement":"Declaration. Ethical Approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed Consent: Informed consent was obtained from all individual participants included in the study. Conflict of Interest: The authors declare no competing interests."},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"accepted"},"Year":"2024","Month":"12","Day":"26"},{"@attributes":{"PubStatus":"medline"},"Year":"2026","Month":"5","Day":"11","Hour":"13","Minute":"0"},{"@attributes":{"PubStatus":"pubmed"},"Year":"2025","Month":"1","Day":"10","Hour":"0","Minute":"21"},{"@attributes":{"PubStatus":"entrez"},"Year":"2025","Month":"1","Day":"9","Hour":"23","Minute":"32"},{"@attributes":{"PubStatus":"pmc-release"},"Year":"2025","Month":"1","Day":"9"}]},"PublicationStatus":"ppublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"39789386"},{"@attributes":{"IdType":"pmc"},"@text":"PMC13161006"},{"@attributes":{"IdType":"doi"},"@text":"10.1007\/s12529-024-10346-7"},{"@attributes":{"IdType":"pii"},"@text":"10.1007\/s12529-024-10346-7"}]},"ReferenceList":[{"Reference":[{"Citation":"Jennings EM, Okine BN, Roche M, Finn DP. Stress-induced hyperalgesia. Prog Neurobiol. 2014;121:1\u201318. 10.1016\/j.pneurobio.2014.06.003.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.pneurobio.2014.06.003"},{"@attributes":{"IdType":"pubmed"},"@text":"25010858"}]}},{"Citation":"Garfin DR, Thompson RR, Holman EA. Acute stress and subsequent health outcomes: A systematic review. J Psychosom Res. 2018;112:107\u201313. 10.1016\/j.jpsychores.2018.05.017.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.jpsychores.2018.05.017"},{"@attributes":{"IdType":"pubmed"},"@text":"30097129"}]}},{"Citation":"Butler RK, Finn DP. Stress-induced analgesia. Prog Neurobiol. 2009;88(3):184\u2013202. 10.1016\/j.pneurobio.2009.04.003.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.pneurobio.2009.04.003"},{"@attributes":{"IdType":"pubmed"},"@text":"19393288"}]}},{"Citation":"Flor H, Grusser SM. Conditioned stress-induced analgesia in humans. Eur J Pain. 1999;3(4):317\u201324. 10.1053\/eujp.1999.0137.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1053\/eujp.1999.0137"},{"@attributes":{"IdType":"pubmed"},"@text":"10700359"}]}},{"Citation":"Lazarus RS, Folkman S. Stress, appraisal, and coping. New York: Springer Pub. Co.; 1984."},{"Citation":"Jackson T, Wang Y, Fan H. Associations between pain appraisals and pain outcomes: meta-analyses of laboratory pain and chronic pain literatures. J Pain. 2014;15(6):586\u2013601. 10.1016\/j.jpain.2014.01.499.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.jpain.2014.01.499"},{"@attributes":{"IdType":"pubmed"},"@text":"24524845"}]}},{"Citation":"Geva N, Pruessner J, Defrin R. Acute psychosocial stress reduces pain modulation capabilities in healthy men. Pain. 2014;155(11):2418\u201325. 10.1016\/j.pain.2014.09.023.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.pain.2014.09.023"},{"@attributes":{"IdType":"pubmed"},"@text":"25250721"}]}},{"Citation":"Tomaka J, Blascovich J, Kibler J, Ernst JM. Cognitive and physiological antecedents of threat and challenge appraisal. J Pers Soc Psychol. 1997;73(1):63\u201372. https:\/\/doi.org\/10.1037\/\/0022-3514.73.1.63.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"9216079"}]}},{"Citation":"Walker LS, Smith CA, Garber J, Claar RL. Appraisal and coping with daily stressors by pediatric patients with chronic abdominal pain. J Pediatr Psychol. 2007;32(2):206\u201316. 10.1093\/jpepsy\/jsj124.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1093\/jpepsy\/jsj124"},{"@attributes":{"IdType":"pmc"},"@text":"PMC3150731"},{"@attributes":{"IdType":"pubmed"},"@text":"16717138"}]}},{"Citation":"Crum AJ, Salovey P, Achor S. Rethinking stress: the role of mindsets in determining the stress response. J Pers Soc Psychol. 2013;104(4):716\u201333. 10.1037\/a0031201.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/a0031201"},{"@attributes":{"IdType":"pubmed"},"@text":"23437923"}]}},{"Citation":"Crum AJ, Akinola M, Martin A, Fath S. The role of stress mindset in shaping cognitive, emotional, and physiological responses to challenging and threatening stress. Anxiety Stress Coping. 2017;30(4):379\u201395. 10.1080\/10615806.2016.1275585.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1080\/10615806.2016.1275585"},{"@attributes":{"IdType":"pubmed"},"@text":"28120622"}]}},{"Citation":"Huebschmann NA, Sheets ES. The right mindset: stress mindset moderates the association between perceived stress and depressive symptoms. Anxiety Stress Coping. 2020;33(3):248\u201355. 10.1080\/10615806.2020.1736900.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1080\/10615806.2020.1736900"},{"@attributes":{"IdType":"pubmed"},"@text":"32138538"}]}},{"Citation":"Smith EN, Young MD, Crum AJ. Stress, mindsets, and success in Navy SEALs special warfare training. Front Psychol. 2020;10:2962.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.3389\/fpsyg.2019.02962"},{"@attributes":{"IdType":"pmc"},"@text":"PMC6974804"},{"@attributes":{"IdType":"pubmed"},"@text":"32010023"}]}},{"Citation":"Heathcote L, Hernandez J, Kronman C, Mahmud F, Crum A, Simons L. \u2018Stress helps me learn and grow\u2019: Does stress mindset matter for children and young adults with chronic pain? J Pain. 2018;19(3):S56.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.jpain.2017.12.137"}]}},{"Citation":"Grunenwald I, Kaluza AJ, Schultze M, van Dick R. Stress Mindset and Social Identification in Chronic Pain Patients and Their Relationship to Coping, Well-Being & Depression. J Clin Psychol Med Settings. 2022. 10.1007\/s10880-022-09883-8.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1007\/s10880-022-09883-8"},{"@attributes":{"IdType":"pmc"},"@text":"PMC10042901"},{"@attributes":{"IdType":"pubmed"},"@text":"35576086"}]}},{"Citation":"Fischer S, Nater UM, Laferton JA. Negative Stress Beliefs Predict Somatic Symptoms in Students Under Academic Stress. Int J Behav Med. 2016;23(6):746\u201351. 10.1007\/s12529-016-9562-y.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1007\/s12529-016-9562-y"},{"@attributes":{"IdType":"pmc"},"@text":"PMC5118394"},{"@attributes":{"IdType":"pubmed"},"@text":"27090420"}]}},{"Citation":"Keech JJ, Hagger MS, O\u2019Callaghan FV, Hamilton K. The Influence of University Students\u2019 Stress Mindsets on Health and Performance Outcomes. Ann Behav Med. 2018;52(12):1046\u201359. 10.1093\/abm\/kay008.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1093\/abm\/kay008"},{"@attributes":{"IdType":"pubmed"},"@text":"30418523"}]}},{"Citation":"Keech JJ, Cole KL, Hagger MS, Hamilton K. The association between stress mindset and physical and psychological wellbeing: testing a stress beliefs model in police officers. Psychol Health. 2020;35(11):1306\u201325. 10.1080\/08870446.2020.1743841.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1080\/08870446.2020.1743841"},{"@attributes":{"IdType":"pubmed"},"@text":"32212946"}]}},{"Citation":"Crum AJ, Jamieson JP, Akinola M. Optimizing stress: An integrated intervention for regulating stress responses. Emotion. 2020;20(1):120\u20135. 10.1037\/emo0000670.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/emo0000670"},{"@attributes":{"IdType":"pmc"},"@text":"PMC7608610"},{"@attributes":{"IdType":"pubmed"},"@text":"31961190"}]}},{"Citation":"Crum AJ, Santoro E, Handley-Miner I, et al. Evaluation of the \u201crethink stress\u201d mindset intervention: A metacognitive approach to changing mindsets. J Exp Psychol Gen. 2023. 10.1037\/xge0001396.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/xge0001396"},{"@attributes":{"IdType":"pubmed"},"@text":"37199967"}]}},{"Citation":"Jamieson JP, Nock MK, Mendes WB. Mind over matter: reappraising arousal improves cardiovascular and cognitive responses to stress. J Exp Psychol Gen. 2012;141(3):417\u201322. 10.1037\/a0025719.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/a0025719"},{"@attributes":{"IdType":"pmc"},"@text":"PMC3410434"},{"@attributes":{"IdType":"pubmed"},"@text":"21942377"}]}},{"Citation":"Hilberdink CE, van Zuiden M, Schrantee A, Korosi A, Kaiser A, Zhutovsky P, Ginty AT, Ensink JBM, Lindauer RJL, Vrijkotte TGM, de Rooij SR. Dysregulated functional brain connectivity in response to acute social-evaluative stress in adolescents with PTSD symptoms. Eur J Psychotraumatol. 2021; 12(1):1880727. 10.1080\/20008198.2021.1880727","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pmc"},"@text":"PMC8075091"},{"@attributes":{"IdType":"pubmed"},"@text":"33968316"}]}},{"Citation":"Wager TD, Waugh CE, Lindquist M, Noll DC, Fredrickson BL, Taylor SF. Brain mediators of cardiovascular responses to social threat, Part I: reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity. Neuroimage. 2009;47:821\u201335. 10.1016\/j.neuroimage.2009.05.043.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.neuroimage.2009.05.043"},{"@attributes":{"IdType":"pmc"},"@text":"PMC3275821"},{"@attributes":{"IdType":"pubmed"},"@text":"19465137"}]}},{"Citation":"Williams SE, Veldhuijzen van Zanten J, Trotman GP, Quinton ML, Ginty AT. Challenge and threat imagery manipulates heart rate and anxiety responses to stress. Int J Psychophysiol. 2017;117:111\u20138. 10.1016\/j.ijpsycho.2017.04.011","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"28461204"}]}},{"Citation":"Gaab J, Rohleder N, Nater UM, Ehlert U. Psychological determinants of the cortisol stress response: the role of anticipatory cognitive appraisal. Psychoneuroendocrino. 2005;30(6):599\u2013610. 10.1016\/j.psyneuen.2005.02.001.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.psyneuen.2005.02.001"},{"@attributes":{"IdType":"pubmed"},"@text":"15808930"}]}},{"Citation":"Sullivan MJ, Bishop SR, Pivik J. The pain catastrophizing scale: development and validation. Psychol Assessment. 1995;7(4):524\u201332. 10.1037\/1040-3590.7.4.524.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/1040-3590.7.4.524"}]}},{"Citation":"Roth RS, Geisser ME, Theisen-Goodvich M, Dixon PJ. Cognitive complaints are associated with depression, fatigue, female sex, and pain catastrophizing in patients with chronic pain. Arch Phys Med Rehabil. 2005;86(6):1147\u201354. 10.1016\/j.apmr.2004.10.041.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.apmr.2004.10.041"},{"@attributes":{"IdType":"pubmed"},"@text":"15954053"}]}},{"Citation":"Goodin BR, McGuire L, Allshouse M, et al. Associations between catastrophizing and endogenous pain-inhibitory processes: sex differences. J Pain. 2009;10(2):180\u201390.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.jpain.2008.08.012"},{"@attributes":{"IdType":"pubmed"},"@text":"19010738"}]}},{"Citation":"Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale, NJ: Erlbaum; 1988."},{"Citation":"Hanssen MM, Peters ML, Vlaeyen JWS, Meevissen YMC, Vancleef LMG. Optimism lowers pain: evidence of the causal status and underlying mechanisms. Pain. 2013;154(1):53\u20138. 10.1016\/j.pain.2012.08.006.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1016\/j.pain.2012.08.006"},{"@attributes":{"IdType":"pubmed"},"@text":"23084002"}]}},{"Citation":"Crum AJ, Heathcote LC, Morrison Z, et al. Changing Mindsets About Side Effects of the COVID-19 Vaccination: A Randomized Controlled Trial. Ann Behav Med. 2023. 10.1093\/abm\/kaad020.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1093\/abm\/kaad020"},{"@attributes":{"IdType":"pmc"},"@text":"PMC10578416"},{"@attributes":{"IdType":"pubmed"},"@text":"37279932"}]}},{"Citation":"Keller A, Litzelman K, Wisk LE, et al. Does the perception that stress affects health matter? The association with health and mortality. Health Psychol. 2012;31(5):677.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1037\/a0026743"},{"@attributes":{"IdType":"pmc"},"@text":"PMC3374921"},{"@attributes":{"IdType":"pubmed"},"@text":"22201278"}]}},{"Citation":"Kirschbaum C, Pirke KM, Hellhammer DH. The \u2019Trier Social Stress Test\u2019\u2013a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology. 1993;28(1\u20132):76\u201381. 10.1159\/000119004.","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"doi"},"@text":"10.1159\/000119004"},{"@attributes":{"IdType":"pubmed"},"@text":"8255414"}]}}]}]}}}