{"PubmedArticle":{"MedlineCitation":{"@attributes":{"Status":"MEDLINE","Owner":"NLM","IndexingMethod":"Automated"},"PMID":{"@attributes":{"Version":"1"},"@text":"40411614"},"DateCompleted":{"Year":"2025","Month":"05","Day":"24"},"DateRevised":{"Year":"2025","Month":"12","Day":"31"},"Article":{"@attributes":{"PubModel":"Electronic"},"Journal":{"ISSN":{"@attributes":{"IssnType":"Electronic"},"@text":"1434-3916"},"JournalIssue":{"@attributes":{"CitedMedium":"Internet"},"Volume":"145","Issue":"1","PubDate":{"Year":"2025","Month":"May","Day":"24"}},"Title":"Archives of orthopaedic and trauma surgery","ISOAbbreviation":"Arch Orthop Trauma Surg"},"ArticleTitle":"No difference in reoperation rates or aseptic loosening following cemented total knee arthroplasty with or without a tourniquet.","Pagination":{"StartPage":"313","MedlinePgn":"313"},"ELocationID":[{"@attributes":{"EIdType":"doi","ValidYN":"Y"},"@text":"10.1007\/s00402-025-05933-6"}],"Abstract":{"AbstractText":[{"@attributes":{"Label":"INTRODUCTION","NlmCategory":"BACKGROUND"},"@text":"The objective of the current study was to evaluate the reoperation rate among patients undergoing cemented total knee arthroplasty (TKA) with or without an intraoperative tourniquet."},{"@attributes":{"Label":"MATERIALS AND METHODS","NlmCategory":"METHODS"},"@text":"A retrospective cohort study of consecutive patients who received a primary, cemented TKA at a high volume academic orthopaedic center. Eligible patients underwent primary, cemented TKA either with or without the use of a tourniquet throughout the entirety of the care. The causes and timing of reoperations were recorded. Survivorship analysis was conducted using Kaplan-Meier curves. Cox proportional hazards models were utilized to evaluate independent predictors of reoperation."},{"@attributes":{"Label":"RESULTS","NlmCategory":"RESULTS"},"@text":"There were 2276 (58%) cases in which a tourniquet was used and 1663 (42%) cases with no tourniquet use. Mean time from the primary TKA was 14.7 years. The cumulative survival at final follow-up for the no tourniquet group and tourniquet group were 92.2% and 96.5%, respectively. Only younger age was an independent predictor of both all cause revision and aseptic loosening."},{"@attributes":{"Label":"CONCLUSIONS","NlmCategory":"CONCLUSIONS"},"@text":"Adjusting for confounders, the presence of a tourniquet did not affect the rates of long-term all-cause revision rates or aseptic loosening. Younger patients have a higher risk of all-cause reoperation and reoperation due to aseptic loosening."},{"@attributes":{"Label":"LEVEL OF EVIDENCE","NlmCategory":"METHODS"},"@text":"Level III."}],"CopyrightInformation":"\u00a9 2025. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature."},"AuthorList":{"@attributes":{"CompleteYN":"Y"},"Author":[{"@attributes":{"ValidYN":"Y"},"LastName":"Gazendam","ForeName":"Aaron","Initials":"A","AffiliationInfo":[{"Affiliation":"McMaster University Division of Orthopaedics, Hamilton, Canada."},{"Affiliation":"Hamilton Arthroplasty Group, Hamilton Health Sciences, Hamilton, Canada."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Abdel Khalik","ForeName":"Hassaan","Initials":"H","AffiliationInfo":[{"Affiliation":"McMaster University Division of Orthopaedics, Hamilton, Canada."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Patel","ForeName":"Mansi","Initials":"M","AffiliationInfo":[{"Affiliation":"McMaster University, Hamilton, Canada."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Ekhtiari","ForeName":"Seper","Initials":"S","AffiliationInfo":[{"Affiliation":"McMaster University Division of Orthopaedics, Hamilton, Canada."},{"Affiliation":"Hamilton Arthroplasty Group, Hamilton Health Sciences, Hamilton, Canada."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Tate","ForeName":"Isabelle","Initials":"I","AffiliationInfo":[{"Affiliation":"Hamilton Arthroplasty Group, Hamilton Health Sciences, Hamilton, Canada. tate@hhsc.ca."}]},{"@attributes":{"ValidYN":"Y"},"LastName":"Wood","ForeName":"Thomas J","Initials":"TJ","AffiliationInfo":[{"Affiliation":"McMaster University Division of Orthopaedics, Hamilton, Canada."},{"Affiliation":"Hamilton Arthroplasty Group, Hamilton Health Sciences, Hamilton, Canada."}]}]},"Language":["eng"],"PublicationTypeList":{"PublicationType":[{"@attributes":{"UI":"D016428"},"@text":"Journal Article"}]},"ArticleDate":[{"@attributes":{"DateType":"Electronic"},"Year":"2025","Month":"05","Day":"24"}]},"MedlineJournalInfo":{"Country":"Germany","MedlineTA":"Arch Orthop Trauma Surg","NlmUniqueID":"9011043","ISSNLinking":"0936-8051"},"ChemicalList":{"Chemical":[{"RegistryNumber":"0","NameOfSubstance":{"@attributes":{"UI":"D001843"},"@text":"Bone Cements"}}]},"CitationSubset":["IM"],"MeshHeadingList":{"MeshHeading":[{"DescriptorName":{"@attributes":{"UI":"D006801","MajorTopicYN":"N"},"@text":"Humans"}},{"DescriptorName":{"@attributes":{"UI":"D019645","MajorTopicYN":"Y"},"@text":"Arthroplasty, Replacement, Knee"},"QualifierName":[{"@attributes":{"UI":"Q000379","MajorTopicYN":"N"},"@text":"methods"}]},{"DescriptorName":{"@attributes":{"UI":"D012086","MajorTopicYN":"N"},"@text":"Reoperation"},"QualifierName":[{"@attributes":{"UI":"Q000706","MajorTopicYN":"N"},"@text":"statistics & numerical data"}]},{"DescriptorName":{"@attributes":{"UI":"D014111","MajorTopicYN":"Y"},"@text":"Tourniquets"}},{"DescriptorName":{"@attributes":{"UI":"D012189","MajorTopicYN":"N"},"@text":"Retrospective Studies"}},{"DescriptorName":{"@attributes":{"UI":"D008297","MajorTopicYN":"N"},"@text":"Male"}},{"DescriptorName":{"@attributes":{"UI":"D000368","MajorTopicYN":"N"},"@text":"Aged"}},{"DescriptorName":{"@attributes":{"UI":"D005260","MajorTopicYN":"N"},"@text":"Female"}},{"DescriptorName":{"@attributes":{"UI":"D011475","MajorTopicYN":"Y"},"@text":"Prosthesis Failure"}},{"DescriptorName":{"@attributes":{"UI":"D008875","MajorTopicYN":"N"},"@text":"Middle Aged"}},{"DescriptorName":{"@attributes":{"UI":"D000369","MajorTopicYN":"N"},"@text":"Aged, 80 and over"}},{"DescriptorName":{"@attributes":{"UI":"D001843","MajorTopicYN":"N"},"@text":"Bone Cements"}}]},"KeywordList":[{"@attributes":{"Owner":"NOTNLM"},"Keyword":[{"@attributes":{"MajorTopicYN":"N"},"@text":"Cemented"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Reoperation"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Revision"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Total knee arthroplasty"},{"@attributes":{"MajorTopicYN":"N"},"@text":"Tourniquet"}]}],"CoiStatement":"Declarations. Competing interests: The authors declare no competing interests."},"PubmedData":{"History":{"PubMedPubDate":[{"@attributes":{"PubStatus":"received"},"Year":"2025","Month":"2","Day":"20"},{"@attributes":{"PubStatus":"accepted"},"Year":"2025","Month":"5","Day":"14"},{"@attributes":{"PubStatus":"medline"},"Year":"2025","Month":"5","Day":"25","Hour":"0","Minute":"45"},{"@attributes":{"PubStatus":"pubmed"},"Year":"2025","Month":"5","Day":"25","Hour":"0","Minute":"44"},{"@attributes":{"PubStatus":"entrez"},"Year":"2025","Month":"5","Day":"24","Hour":"11","Minute":"15"}]},"PublicationStatus":"epublish","ArticleIdList":{"ArticleId":[{"@attributes":{"IdType":"pubmed"},"@text":"40411614"},{"@attributes":{"IdType":"doi"},"@text":"10.1007\/s00402-025-05933-6"},{"@attributes":{"IdType":"pii"},"@text":"10.1007\/s00402-025-05933-6"}]},"ReferenceList":[{"Reference":[{"Citation":"Gazendam A, Wood TJ (2021) Cochrane in CORR<sup>\u00ae<\/sup>: tourniquet use for knee replacement surgery. 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