テンプレート:PBB/6774のソースを表示

{{GNF_Protein_box
 | Name = Signal transducer and activator of transcription 3 (acute-phase response factor)
 | image = stat3_structure.png
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1bg1.
 | PDB = {{PDB2|1bg1}}
 | HGNCid = 11364
 | MGIid = 103038
 | Symbol = STAT3
 | AltSymbols =; APRF; HIES
 | IUPHAR = 
 | ChEMBL = 4026
 | OMIM = 102582
 | ECnumber = 
 | Homologene = 7960
 | GeneAtlas_image1 = PBB_GE_STAT3_208991_at_tn.png
 | GeneAtlas_image2 = PBB_GE_STAT3_208992_s_at_tn.png
 | GeneAtlas_image3 = PBB_GE_STAT3_gnf1h01250_at_tn.png
 <!-- The Following entry is a time stamp of the last bot update.  It is typically hidden data -->
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003700 |text = sequence-specific DNA binding transcription factor activity}} {{GNF_GO|id=GO:0004871 |text = signal transducer activity}} {{GNF_GO|id=GO:0004879 |text = ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008134 |text = transcription factor binding}} {{GNF_GO|id=GO:0019901 |text = protein kinase binding}} {{GNF_GO|id=GO:0031730 |text = CCR5 chemokine receptor binding}} {{GNF_GO|id=GO:0035259 |text = glucocorticoid receptor binding}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0044212 |text = transcription regulatory region DNA binding}} {{GNF_GO|id=GO:0046983 |text = protein dimerization activity}}
 | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005654 |text = nucleoplasm}} {{GNF_GO|id=GO:0005730 |text = nucleolus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005829 |text = cytosol}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}}
 | Process = {{GNF_GO|id=GO:0000122 |text = negative regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0001659 |text = temperature homeostasis}} {{GNF_GO|id=GO:0001754 |text = eye photoreceptor cell differentiation}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006606 |text = protein import into nucleus}} {{GNF_GO|id=GO:0006928 |text = cellular component movement}} {{GNF_GO|id=GO:0006953 |text = acute-phase response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007259 |text = JAK-STAT cascade}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0014070 |text = response to organic cyclic compound}} {{GNF_GO|id=GO:0019048 |text = virus-host interaction}} {{GNF_GO|id=GO:0019221 |text = cytokine-mediated signaling pathway}} {{GNF_GO|id=GO:0019953 |text = sexual reproduction}} {{GNF_GO|id=GO:0030522 |text = intracellular receptor mediated signaling pathway}} {{GNF_GO|id=GO:0032355 |text = response to estradiol stimulus}} {{GNF_GO|id=GO:0032870 |text = cellular response to hormone stimulus}} {{GNF_GO|id=GO:0040014 |text = regulation of multicellular organism growth}} {{GNF_GO|id=GO:0042493 |text = response to drug}} {{GNF_GO|id=GO:0042593 |text = glucose homeostasis}} {{GNF_GO|id=GO:0042755 |text = eating behavior}} {{GNF_GO|id=GO:0045471 |text = response to ethanol}} {{GNF_GO|id=GO:0045747 |text = positive regulation of Notch signaling pathway}} {{GNF_GO|id=GO:0045893 |text = positive regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0048011 |text = nerve growth factor receptor signaling pathway}} {{GNF_GO|id=GO:0048708 |text = astrocyte differentiation}} {{GNF_GO|id=GO:0060019 |text = radial glial cell differentiation}} {{GNF_GO|id=GO:0060396 |text = growth hormone receptor signaling pathway}} {{GNF_GO|id=GO:0060397 |text = JAK-STAT cascade involved in growth hormone signaling pathway}} {{GNF_GO|id=GO:0070102 |text = interleukin-6-mediated signaling pathway}}
 | Hs_EntrezGene = 6774
 | Hs_Ensembl = ENSG00000168610
 | Hs_RefseqmRNA = NM_003150.3
 | Hs_RefseqProtein = NP_003141.2
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 17
 | Hs_GenLoc_start = 40465342
 | Hs_GenLoc_end = 40540449
 | Hs_Uniprot = P40763
 | Mm_EntrezGene = 20848
 | Mm_Ensembl = ENSMUSG00000004040
 | Mm_RefseqmRNA = NM_011486.4
 | Mm_RefseqProtein = NP_035616.1
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 11
 | Mm_GenLoc_start = 100885098
 | Mm_GenLoc_end = 100939540
 | Mm_Uniprot = P42227
 | path = PBB/6774
}}