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{| class="wikitable" |+ 表1. |- | Classification||Target ||Year||Probe design ||References |- | Small molecule || カルシウム || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref> |- | Small molecule || サイクリックGMP (cGMP) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref> |- | Small molecule || サイクリックAMP (cAMP) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref> |- | Small molecule || イノシトール3リン酸 (IP3) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref> |- | Small molecule || 一酸化窒素 (NO) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref> |- | Small molecule || アデノシン3リン酸 (ATP) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref> |- | Small molecule || エストロゲン || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref> |- | Small molecule || アンドロゲン || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref> |- | Small molecule || グルココルチコイド受容体リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref> |- | Small molecule || 神経成長因子 || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref> |- | Small molecule || 核内受容体 || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref> |- | Small molecule || O-N-アセチルグルコサミン (O-GlcNAc) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref> |- | Small molecule || ビタミンA (レチノイン酸) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref> |- | Small molecule || モリブデン酸 || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref> |- | Small molecule || グルタミン酸 || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref> |- | Small molecule || Zn<sup>2+</sup> || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref> |- | Small molecule || Cl<sup>-</sup> || 2000 || other || <ref><pubmed>11055428</pubmed></ref> |- | Small molecule || 水素イオン濃度 (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref> |- | Small molecule || グルコース || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref> |- | Small molecule || Maltose || 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref> |- | Small molecule || Ribose || 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref> |- | Kinase || Calcium/Calmodulin-dependent protein kinase II (CaMKII) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref> |- | Kinase || Src || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref> |- | Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref> |- | Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref> |- | Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148, 11752448</pubmed></ref> |- Table 1 A list of genetically encoded FRET probes. | Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> |- | Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref> |- The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information. | Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref> |- | Kinase || PAK1 || 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref> |- | Kinase || B-raf || 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref> |- | Kinase || ZAP-70 || 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref> |- | Kinase || Akt || 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref> |- | Kinase || ERK || 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref> |- | Kinase || Insulin receptor || 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref> |- | Kinase || Epidermal Growth factor receptor (EGFR) || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> |- | Kinase || Ataxia telangiectasia mutated (ATM) || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref> |- | Kinase || Aurora B kinase || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref> |- | Kinase || Cyclin B1-CDK1 || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref> |- | Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref> |- | Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref><pubmed> 21976697</pubmed></ref> |- | Kinase || RSK || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref> |- | Kinase || S6K || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref> |- | Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref> |- | Kinase || PLK1 || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref> |- | Kinase || SAP3K || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref> |- | Kinase || DAPK1 || 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref> |- | Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref> |- | Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref><pubmed> 11429608</pubmed></ref> |- | Small GTPase || Rap || 2001 || 3-2 || <ref><pubmed>11429608</pubmed></ref> |- | Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref> |- | Small GTPase || Rab5 || 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref> |- | Small GTPase || Rho || 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref> |- | Small GTPase || Cdc42 || 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref> |- | Small GTPase || Ral || 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref> |- | Small GTPase || TC10 || 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref> |- | Signal transduction || RCC1(GEF of Ran) || 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref> |- | Signal transduction || CrkII phosphorylation || 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref> |- | Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref> |- | Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref> |- | Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref> |- | Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref> |- | Acetylation || Histone acetylation || 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref> |- | Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref> |- | Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref> |- | Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref> |- | Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref> |- | Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref> |- | Lipid || Diacylglycerol (DAG) || 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref> |- | Protein interaction || Actin || 2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref> |- | Protein interaction || PDK1-Akt interaction || 2007 || 2 || <ref><pubmed>17407381</pubmed></ref> |- | Protein interaction || Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref> |- | Protein interaction || Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || 2010 || 2 || <ref><pubmed>20622991</pubmed></ref> |- | Protein interaction || Cofiin-actin interaction || 2008 || 2 || <ref><pubmed>17993279</pubmed></ref> |- | Protein interaction || PTEN-Myosin V interaction || 2009 || 2 || <ref><pubmed>19767745</pubmed></ref> |- | Protease || Caspase-3 || 1998 || 1 || <ref><pubmed>9518501</pubmed></ref> |- | Protease || Caspase-8 || 2002 || 1 || <ref><pubmed>12409609</pubmed></ref> |- | Protease || Caspase-9 || 2011 || 1 || <ref><pubmed>21637712</pubmed></ref> |- | Protease || Caspase-7 || 2006 || 1 || <ref><pubmed>17946841</pubmed></ref> |- | Protease || Matrix Metalloproteinase (MMP) || 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref> |- | Protease || Protease activity (Factor Xa) || 1996 || 1 || <ref><pubmed>8707050</pubmed></ref> |- | Protease || Calpain activity || 2000 || 1 || <ref><pubmed>10688895</pubmed></ref> |- | Protease || Presenilin || 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref> |- | Other || Strain sensor || 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref> |- | Other || Membrane potential || 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref> |- | Other || Myosin II || 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref> |- | Other || HIV Rev protein || 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref> |- | Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref> |- } <references />
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