テンプレート:PBB/85358のソースを表示

{{GNF_Protein_box
 | Name = SH3 and multiple ankyrin repeat domains 3
 | image = Protein_SHANK3_PDB_2f3n.png
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 2f3n.
 | PDB = 
 | HGNCid = 14294
 | MGIid = 1930016
 | Symbol = SHANK3
 | AltSymbols =; DEL22q13.3; PROSAP2; PSAP2; SCZD15; SPANK-2
 | IUPHAR = 
 | ChEMBL = 
 | OMIM = 606230
 | ECnumber = 
 | Homologene = 75163
 | GeneAtlas_image1 = PBB_GE_SHANK3_gnf1h01748_s_at_tn.png
 | GeneAtlas_image2 = PBB_GE_SHANK3_gnf1h02526_x_at_tn.png
 | GeneAtlas_image3 = PBB_GE_SHANK3_gnf1h02529_at_tn.png
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008022 |text = protein C-terminus binding}} {{GNF_GO|id=GO:0017124 |text = SH3 domain binding}} {{GNF_GO|id=GO:0030160 |text = GKAP/Homer scaffold activity}} {{GNF_GO|id=GO:0035255 |text = ionotropic glutamate receptor binding}} {{GNF_GO|id=GO:0097110 |text = scaffold protein binding}}
 | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0014069 |text = postsynaptic density}} {{GNF_GO|id=GO:0030054 |text = cell junction}} {{GNF_GO|id=GO:0044309 |text = neuron spine}} {{GNF_GO|id=GO:0045202 |text = synapse}} {{GNF_GO|id=GO:0045211 |text = postsynaptic membrane}}
 | Process = {{GNF_GO|id=GO:0021773 |text = striatal medium spiny neuron differentiation}} {{GNF_GO|id=GO:0035176 |text = social behavior}} {{GNF_GO|id=GO:0035641 |text = locomotory exploration behavior}} {{GNF_GO|id=GO:0045794 |text = negative regulation of cell volume}} {{GNF_GO|id=GO:0048170 |text = positive regulation of long-term neuronal synaptic plasticity}} {{GNF_GO|id=GO:0048854 |text = brain morphogenesis}} {{GNF_GO|id=GO:0051835 |text = positive regulation of synapse structural plasticity}} {{GNF_GO|id=GO:0051968 |text = positive regulation of synaptic transmission, glutamatergic}} {{GNF_GO|id=GO:0060997 |text = dendritic spine morphogenesis}} {{GNF_GO|id=GO:0071625 |text = vocalization behavior}} {{GNF_GO|id=GO:0097107 |text = postsynaptic density assembly}} {{GNF_GO|id=GO:2000463 |text = positive regulation of excitatory postsynaptic membrane potential}} {{GNF_GO|id=GO:2000822 |text = regulation of behavioral fear response}} {{GNF_GO|id=GO:2000969 |text = positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity}}
 | Hs_EntrezGene = 85358
 | Hs_Ensembl = ENSG00000251322
 | Hs_RefseqmRNA = NM_001080420.1
 | Hs_RefseqProtein = NP_001073889.1
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 22
 | Hs_GenLoc_start = 51113070
 | Hs_GenLoc_end = 51171641
 | Hs_Uniprot = F2Z3L0
 | Mm_EntrezGene = 58234
 | Mm_Ensembl = ENSMUSG00000022623
 | Mm_RefseqmRNA = NM_021423.3
 | Mm_RefseqProtein = NP_067398.2
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 15
 | Mm_GenLoc_start = 89330054
 | Mm_GenLoc_end = 89390692
 | Mm_Uniprot = Q4ACU6
 | path = PBB/85358
}}