テンプレート:PBB/1020のソースを表示

{{GNF_Protein_box
 |image=1H4L.pdb
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1H4L.
 | PDB = {{PDB2|1H4L}}, {{PDB2|1UNG}}, {{PDB2|1UNH}}, {{PDB2|1UNL}}, {{PDB2|3O0G}}, {{PDB2|4AU8}}
 | HGNCid = 1774
 | MGIid = 101765
 | Symbol = CDK5
 | AltSymbols =; PSSALRE
 | IUPHAR = 
 | ChEMBL = 4036
 | OMIM = 123831
 | ECnumber = 2.7.11.22
 | Homologene = 3623
 | GeneAtlas_image1 = PBB_GE_CDK5_204247_s_at_tn.png
 | GeneAtlas_image2 = 
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0002039 |text = p53 binding}} {{GNF_GO|id=GO:0004672 |text = protein kinase activity}} {{GNF_GO|id=GO:0004674 |text = protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0004693 |text = cyclin-dependent protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0005176 |text = ErbB-2 class receptor binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016301 |text = kinase activity}} {{GNF_GO|id=GO:0030549 |text = acetylcholine receptor activator activity}} {{GNF_GO|id=GO:0043125 |text = ErbB-3 class receptor binding}} {{GNF_GO|id=GO:0046875 |text = ephrin receptor binding}} {{GNF_GO|id=GO:0050321 |text = tau-protein kinase activity}}
 | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005829 |text = cytosol}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0014069 |text = postsynaptic density}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016533 |text = cyclin-dependent protein kinase 5 holoenzyme complex}} {{GNF_GO|id=GO:0030027 |text = lamellipodium}} {{GNF_GO|id=GO:0030054 |text = cell junction}} {{GNF_GO|id=GO:0030175 |text = filopodium}} {{GNF_GO|id=GO:0030424 |text = axon}} {{GNF_GO|id=GO:0030425 |text = dendrite}} {{GNF_GO|id=GO:0030426 |text = growth cone}} {{GNF_GO|id=GO:0031594 |text = neuromuscular junction}} {{GNF_GO|id=GO:0043025 |text = neuronal cell body}} {{GNF_GO|id=GO:0043204 |text = perikaryon}} {{GNF_GO|id=GO:0045211 |text = postsynaptic membrane}}
 | Process = {{GNF_GO|id=GO:0001764 |text = neuron migration}} {{GNF_GO|id=GO:0001963 |text = synaptic transmission, dopaminergic}} {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0006913 |text = nucleocytoplasmic transport}} {{GNF_GO|id=GO:0007160 |text = cell-matrix adhesion}} {{GNF_GO|id=GO:0007268 |text = synaptic transmission}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0007416 |text = synapse assembly}} {{GNF_GO|id=GO:0007519 |text = skeletal muscle tissue development}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}} {{GNF_GO|id=GO:0008045 |text = motor neuron axon guidance}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0008542 |text = visual learning}} {{GNF_GO|id=GO:0009790 |text = embryo development}} {{GNF_GO|id=GO:0014044 |text = Schwann cell development}} {{GNF_GO|id=GO:0016079 |text = synaptic vesicle exocytosis}} {{GNF_GO|id=GO:0016310 |text = phosphorylation}} {{GNF_GO|id=GO:0018105 |text = peptidyl-serine phosphorylation}} {{GNF_GO|id=GO:0018107 |text = peptidyl-threonine phosphorylation}} {{GNF_GO|id=GO:0019233 |text = sensory perception of pain}} {{GNF_GO|id=GO:0021697 |text = cerebellar cortex formation}} {{GNF_GO|id=GO:0021766 |text = hippocampus development}} {{GNF_GO|id=GO:0021819 |text = layer formation in cerebral cortex}} {{GNF_GO|id=GO:0021954 |text = central nervous system neuron development}} {{GNF_GO|id=GO:0022038 |text = corpus callosum development}} {{GNF_GO|id=GO:0030182 |text = neuron differentiation}} {{GNF_GO|id=GO:0030334 |text = regulation of cell migration}} {{GNF_GO|id=GO:0030866 |text = cortical actin cytoskeleton organization}} {{GNF_GO|id=GO:0031175 |text = neuron projection development}} {{GNF_GO|id=GO:0031397 |text = negative regulation of protein ubiquitination}} {{GNF_GO|id=GO:0031914 |text = negative regulation of synaptic plasticity}} {{GNF_GO|id=GO:0032092 |text = positive regulation of protein binding}} {{GNF_GO|id=GO:0032801 |text = receptor catabolic process}} {{GNF_GO|id=GO:0033136 |text = serine phosphorylation of STAT3 protein}} {{GNF_GO|id=GO:0035249 |text = synaptic transmission, glutamatergic}} {{GNF_GO|id=GO:0035418 |text = protein localization to synapse}} {{GNF_GO|id=GO:0042981 |text = regulation of apoptotic process}} {{GNF_GO|id=GO:0043113 |text = receptor clustering}} {{GNF_GO|id=GO:0043525 |text = positive regulation of neuron apoptotic process}} {{GNF_GO|id=GO:0045055 |text = regulated secretory pathway}} {{GNF_GO|id=GO:0045786 |text = negative regulation of cell cycle}} {{GNF_GO|id=GO:0045860 |text = positive regulation of protein kinase activity}} {{GNF_GO|id=GO:0045892 |text = negative regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0045956 |text = positive regulation of calcium ion-dependent exocytosis}} {{GNF_GO|id=GO:0046777 |text = protein autophosphorylation}} {{GNF_GO|id=GO:0046826 |text = negative regulation of protein export from nucleus}} {{GNF_GO|id=GO:0048148 |text = behavioral response to cocaine}} {{GNF_GO|id=GO:0048167 |text = regulation of synaptic plasticity}} {{GNF_GO|id=GO:0048488 |text = synaptic vesicle endocytosis}} {{GNF_GO|id=GO:0048675 |text = axon extension}} {{GNF_GO|id=GO:0048709 |text = oligodendrocyte differentiation}} {{GNF_GO|id=GO:0048813 |text = dendrite morphogenesis}} {{GNF_GO|id=GO:0051301 |text = cell division}} {{GNF_GO|id=GO:0051402 |text = neuron apoptotic process}} {{GNF_GO|id=GO:0060079 |text = regulation of excitatory postsynaptic membrane potential}} {{GNF_GO|id=GO:0061001 |text = regulation of dendritic spine morphogenesis}} {{GNF_GO|id=GO:0070509 |text = calcium ion import}} {{GNF_GO|id=GO:0071156 |text = regulation of cell cycle arrest}} {{GNF_GO|id=GO:0090314 |text = positive regulation of protein targeting to membrane}} {{GNF_GO|id=GO:2000251 |text = positive regulation of actin cytoskeleton reorganization}}
 | Hs_EntrezGene = 1020
 | Hs_Ensembl = ENSG00000164885
 | Hs_RefseqmRNA = NM_001164410
 | Hs_RefseqProtein = NP_001157882
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 7
 | Hs_GenLoc_start = 150750899
 | Hs_GenLoc_end = 150755617
 | Hs_Uniprot = Q00535
 | Mm_EntrezGene = 12568
 | Mm_Ensembl = ENSMUSG00000028969
 | Mm_RefseqmRNA = NM_007668
 | Mm_RefseqProtein = NP_031694
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 5
 | Mm_GenLoc_start = 24418250
 | Mm_GenLoc_end = 24423530
 | Mm_Uniprot = P49615
 | path = PBB/1020
}}