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テンプレート:PBB/3084
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{{GNF_Protein_box | Name = Neuregulin 1 | image = Protein_NRG1_PDB_1hae.png | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1hae. | PDB = {{PDB2|1HAE}}, {{PDB2|1HAF}}, {{PDB2|1HRE}}, {{PDB2|1HRF}} | HGNCid = 7997 | MGIid = 96083 | Symbol = NRG1 | AltSymbols =; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; NDF; SMDF | OMIM = 142445 | ECnumber = | Homologene = 8509 | GeneAtlas_image1 = PBB_GE_NRG1_206343_s_at_tn.png | GeneAtlas_image2 = | GeneAtlas_image3 = | Protein_domain_image = | Function = {{GNF_GO|id=GO:0003712 |text = transcription cofactor activity}} {{GNF_GO|id=GO:0005102 |text = receptor binding}} {{GNF_GO|id=GO:0005125 |text = cytokine activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008083 |text = growth factor activity}} {{GNF_GO|id=GO:0008083 |text = growth factor activity}} {{GNF_GO|id=GO:0030296 |text = protein tyrosine kinase activator activity}} {{GNF_GO|id=GO:0030297 |text = transmembrane receptor protein tyrosine kinase activator activity}} {{GNF_GO|id=GO:0030297 |text = transmembrane receptor protein tyrosine kinase activator activity}} {{GNF_GO|id=GO:0030971 |text = receptor tyrosine kinase binding}} {{GNF_GO|id=GO:0043125 |text = ErbB-3 class receptor binding}} {{GNF_GO|id=GO:0043125 |text = ErbB-3 class receptor binding}} | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0016324 |text = apical plasma membrane}} | Process = {{GNF_GO|id=GO:0006916 |text = anti-apoptosis}} {{GNF_GO|id=GO:0007154 |text = cell communication}} {{GNF_GO|id=GO:0007169 |text = transmembrane receptor protein tyrosine kinase signaling pathway}} {{GNF_GO|id=GO:0007171 |text = activation of transmembrane receptor protein tyrosine kinase activity}} {{GNF_GO|id=GO:0007219 |text = Notch signaling pathway}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0009790 |text = embryo development}} {{GNF_GO|id=GO:0010667 |text = negative regulation of cardiac muscle cell apoptosis}} {{GNF_GO|id=GO:0014032 |text = neural crest cell development}} {{GNF_GO|id=GO:0030307 |text = positive regulation of cell growth}} {{GNF_GO|id=GO:0030879 |text = mammary gland development}} {{GNF_GO|id=GO:0042060 |text = wound healing}} {{GNF_GO|id=GO:0042060 |text = wound healing}} {{GNF_GO|id=GO:0043496 |text = regulation of protein homodimerization activity}} {{GNF_GO|id=GO:0043497 |text = regulation of protein heterodimerization activity}} {{GNF_GO|id=GO:0043624 |text = cellular protein complex disassembly}} {{GNF_GO|id=GO:0045785 |text = positive regulation of cell adhesion}} {{GNF_GO|id=GO:0045892 |text = negative regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0051048 |text = negative regulation of secretion}} {{GNF_GO|id=GO:0051155 |text = positive regulation of striated muscle cell differentiation}} {{GNF_GO|id=GO:0055007 |text = cardiac muscle cell differentiation}} {{GNF_GO|id=GO:0055012 |text = ventricular cardiac muscle cell differentiation}} {{GNF_GO|id=GO:0060045 |text = positive regulation of cardiac muscle cell proliferation}} {{GNF_GO|id=GO:0061098 |text = positive regulation of protein tyrosine kinase activity}} | Hs_EntrezGene = 3084 | Hs_Ensembl = ENSG00000157168 | Hs_RefseqmRNA = NM_001159995.1 | Hs_RefseqProtein = NP_001153467.1 | Hs_GenLoc_db = hg19 | Hs_GenLoc_chr = 8 | Hs_GenLoc_start = 31496902 | Hs_GenLoc_end = 32622548 | Hs_Uniprot = Q02297 | Mm_EntrezGene = 211323 | Mm_Ensembl = ENSMUSG00000062991 | Mm_RefseqmRNA = NM_178591.2 | Mm_RefseqProtein = NP_848706.2 | Mm_GenLoc_db = mm9 | Mm_GenLoc_chr = 8 | Mm_GenLoc_start = 32928500 | Mm_GenLoc_end = 33119581 | Mm_Uniprot = }}
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