テンプレート:PBB/5649のソースを表示

{{GNF_Protein_box
 | Name = Reelin
 | image = 2DDU.pdb
 | image_source = Crystallographic structure of the third reelin repeat domain based on {{PDB|2ddu}}<ref><pubmed>16858396</pubmed></ref>.
 | PDB = {{PDB2|2ddu}}, {{PDB2|2e26}}
 | HGNCid = 9957
 | MGIid = 103022
 | Symbol = RELN
 | AltSymbols =; LIS2; PRO1598; RL
 | IUPHAR = 
 | ChEMBL = 
 | OMIM = 600514
 | ECnumber = 3.4.21.-
 | Homologene = 3699
 | GeneAtlas_image1 = PBB_GE_RELN_205923_at_tn.png
 | GeneAtlas_image2 = 
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0004712 |text = protein serine/threonine/tyrosine kinase activity}} {{GNF_GO|id=GO:0008236 |text = serine-type peptidase activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}} {{GNF_GO|id=GO:0070325 |text = lipoprotein particle receptor binding}} {{GNF_GO|id=GO:0070326 |text = very-low-density lipoprotein particle receptor binding}}
 | Component = {{GNF_GO|id=GO:0005578 |text = proteinaceous extracellular matrix}} {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0030425 |text = dendrite}}
 | Process = {{GNF_GO|id=GO:0000904 |text = cell morphogenesis involved in differentiation}} {{GNF_GO|id=GO:0001764 |text = neuron migration}} {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0007417 |text = central nervous system development}} {{GNF_GO|id=GO:0007420 |text = brain development}} {{GNF_GO|id=GO:0007616 |text = long-term memory}} {{GNF_GO|id=GO:0008306 |text = associative learning}} {{GNF_GO|id=GO:0010001 |text = glial cell differentiation}} {{GNF_GO|id=GO:0010976 |text = positive regulation of neuron projection development}} {{GNF_GO|id=GO:0014068 |text = positive regulation of phosphatidylinositol 3-kinase cascade}} {{GNF_GO|id=GO:0016358 |text = dendrite development}} {{GNF_GO|id=GO:0018108 |text = peptidyl-tyrosine phosphorylation}} {{GNF_GO|id=GO:0021511 |text = spinal cord patterning}} {{GNF_GO|id=GO:0021517 |text = ventral spinal cord development}} {{GNF_GO|id=GO:0021766 |text = hippocampus development}} {{GNF_GO|id=GO:0021800 |text = cerebral cortex tangential migration}} {{GNF_GO|id=GO:0032008 |text = positive regulation of TOR signaling cascade}} {{GNF_GO|id=GO:0032793 |text = positive regulation of CREB transcription factor activity}} {{GNF_GO|id=GO:0038026 |text = reelin-mediated signaling pathway}} {{GNF_GO|id=GO:0045860 |text = positive regulation of protein kinase activity}} {{GNF_GO|id=GO:0048265 |text = response to pain}} {{GNF_GO|id=GO:0050731 |text = positive regulation of peptidyl-tyrosine phosphorylation}} {{GNF_GO|id=GO:0050795 |text = regulation of behavior}} {{GNF_GO|id=GO:0050804 |text = regulation of synaptic transmission}} {{GNF_GO|id=GO:0051057 |text = positive regulation of small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0051968 |text = positive regulation of synaptic transmission, glutamatergic}} {{GNF_GO|id=GO:0061003 |text = positive regulation of dendritic spine morphogenesis}} {{GNF_GO|id=GO:0061098 |text = positive regulation of protein tyrosine kinase activity}} {{GNF_GO|id=GO:0090129 |text = positive regulation of synapse maturation}} {{GNF_GO|id=GO:0097114 |text = N-methyl-D-aspartate receptor clustering}} {{GNF_GO|id=GO:0097119 |text = postsynaptic density protein 95 clustering}} {{GNF_GO|id=GO:0097120 |text = receptor localization to synapse}} {{GNF_GO|id=GO:1900273 |text = positive regulation of long-term synaptic potentiation}} {{GNF_GO|id=GO:2000310 |text = regulation of N-methyl-D-aspartate selective glutamate receptor activity}} {{GNF_GO|id=GO:2000463 |text = positive regulation of excitatory postsynaptic membrane potential}} {{GNF_GO|id=GO:2000969 |text = positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity}}
 | Hs_EntrezGene = 5649
 | Hs_Ensembl = ENSG00000189056
 | Hs_RefseqmRNA = NM_005045
 | Hs_RefseqProtein = NP_005036
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 7
 | Hs_GenLoc_start = 103112231
 | Hs_GenLoc_end = 103629963
 | Hs_Uniprot = P78509
 | Mm_EntrezGene = 19699
 | Mm_Ensembl = ENSMUSG00000042453
 | Mm_RefseqmRNA = NM_011261
 | Mm_RefseqProtein = NP_035391
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 5
 | Mm_GenLoc_start = 21884454
 | Mm_GenLoc_end = 22344702
 | Mm_Uniprot = Q60841
 | path = PBB/5649
}}
<noinclude>{{Template reference list}}</noinclude>