テンプレート:PBB/2668のソースを表示

{{GNF_Protein_box
 | Name = Glial cell derived neurotrophic factor
 | image = GDNF.jpg
 | image_source = GDNF structure
 | PDB = {{PDB2|2V5E}}, {{PDB2|3FUB}}
 | HGNCid = 4232
 | MGIid = 107430
 | Symbol = GDNF
 | AltSymbols =; ATF1; ATF2; HFB1-GDNF; HSCR3
 | IUPHAR = 
 | OMIM = 600837
 | ECnumber = 
 | Homologene = 433
 | GeneAtlas_image1 = PBB_GE_GDNF_221359_at_tn.png
 | GeneAtlas_image2 = 
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0005102 |text = receptor binding}} {{GNF_GO|id=GO:0008083 |text = growth factor activity}} {{GNF_GO|id=GO:0042803 |text = protein homodimerization activity}}
 | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}}
 | Process = {{GNF_GO|id=GO:0001656 |text = metanephros development}} {{GNF_GO|id=GO:0001657 |text = ureteric bud development}} {{GNF_GO|id=GO:0001658 |text = branching involved in ureteric bud morphogenesis}} {{GNF_GO|id=GO:0001755 |text = neural crest cell migration}} {{GNF_GO|id=GO:0001759 |text = organ induction}} {{GNF_GO|id=GO:0001941 |text = postsynaptic membrane organization}} {{GNF_GO|id=GO:0006916 |text = anti-apoptosis}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0008344 |text = adult locomotory behavior}} {{GNF_GO|id=GO:0021784 |text = postganglionic parasympathetic nervous system development}} {{GNF_GO|id=GO:0030432 |text = peristalsis}} {{GNF_GO|id=GO:0031175 |text = neuron projection development}} {{GNF_GO|id=GO:0032770 |text = positive regulation of monooxygenase activity}} {{GNF_GO|id=GO:0033603 |text = positive regulation of dopamine secretion}} {{GNF_GO|id=GO:0043524 |text = negative regulation of neuron apoptosis}} {{GNF_GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0048255 |text = mRNA stabilization}} {{GNF_GO|id=GO:0048484 |text = enteric nervous system development}} {{GNF_GO|id=GO:0048485 |text = sympathetic nervous system development}} {{GNF_GO|id=GO:0051584 |text = regulation of dopamine uptake}} {{GNF_GO|id=GO:0060688 |text = regulation of morphogenesis of a branching structure}} {{GNF_GO|id=GO:0072107 |text = positive regulation of ureteric bud formation}} {{GNF_GO|id=GO:0072108 |text = positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis}} {{GNF_GO|id=GO:0090190 |text = positive regulation of branching involved in ureteric bud morphogenesis}} {{GNF_GO|id=GO:2001240 |text = negative regulation of extrinsic apoptotic signaling pathway in absence of ligand}}
 | Hs_EntrezGene = 2668
 | Hs_Ensembl = ENSG00000168621
 | Hs_RefseqmRNA = NM_000514.3
 | Hs_RefseqProtein = NP_000505.1
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 5
 | Hs_GenLoc_start = 37812779
 | Hs_GenLoc_end = 37839788
 | Hs_Uniprot = P39905
 | Mm_EntrezGene = 14573
 | Mm_Ensembl = ENSMUSG00000022144
 | Mm_RefseqmRNA = NM_010275.2
 | Mm_RefseqProtein = NP_034405.1
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 15
 | Mm_GenLoc_start = 7761011
 | Mm_GenLoc_end = 7787575
 | Mm_Uniprot = P48540
}}