https://bsd.neuroinf.jp/w/index.php?action=history&feed=atom&title=4-Methoxyestradiol
4-Methoxyestradiol - 版の履歴
2026-04-12T10:58:35Z
このウィキのこのページに関する変更履歴
MediaWiki 1.43.8
https://bsd.neuroinf.jp/w/index.php?title=4-Methoxyestradiol&diff=49732&oldid=prev
WikiSysop: 1版 をインポートしました
2025-03-18T10:27:22Z
<p>1版 をインポートしました</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="ja">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2025年3月18日 (火) 19:27時点における版</td>
</tr><tr><td colspan="4" class="diff-notice" lang="ja"><div class="mw-diff-empty">(相違点なし)</div>
</td></tr>
<!-- diff cache key wiki-mw_:diff:1.41:old-49731:rev-49732 -->
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=4-Methoxyestradiol&diff=49731&oldid=prev
bsd>LegionMammal978: move semisystematic name
2023-04-27T14:24:40Z
<p>move semisystematic name</p>
<p><b>新規ページ</b></p><div>{{Chembox<br />
<!-- Images --><br />
| ImageFile = 4-Methoxyestradiol.svg<br />
| ImageSize = 200px<br />
| ImageAlt =<br />
<!-- Names --><br />
| IUPACName = 4-Methoxyestra-1,3,5(10)-triene-3,17β-diol<br />
| SystematicName = (1''S'',3a''S'',3b''R'',9b''S'',11a''S'')-6-Methoxy-11a-methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1''H''-cyclopenta[''a'']phenanthrene-1,7-diol<br />
| OtherNames = 4-ME2; 4-MeOE2; 4-MeO-E2; 4-Methoxy-17β-estradiol; Estra-1,3,5(10)-trien-3,4,17β-triol 4-methyl ether<br />
<!-- Sections --><br />
| Section1 = {{Chembox Identifiers<br />
| CASNo = 26788-23-8<br />
| ChemSpiderID = 61848<br />
| ChEBI = 136975<br />
| PubChem = 68578<br />
| StdInChI = 1S/C19H26O3/c1-19-10-9-12-11-5-7-16(20)18(22-2)14(11)4-3-13(12)15(19)6-8-17(19)21/h5,7,12-13,15,17,20-21H,3-4,6,8-10H2,1-2H3/t12-,13-,15+,17+,19+/m1/s1<br />
| StdInChIKey = BCWZIZLVBYHFES-PYEWSWHRSA-N<br />
| SMILES = C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4OC)O<br />
}}<br />
| Section2 = {{Chembox Properties<br />
| C=19 | H=26 | O=3<br />
| Appearance = <br />
| Density = <br />
| MeltingPt = <br />
| BoilingPt = <br />
| Solubility = <br />
}}<br />
| Section3 = {{Chembox Hazards<br />
| MainHazards =<br />
| FlashPt =<br />
| AutoignitionPt =<br />
}}<br />
}}<br />
<br />
'''4-Methoxyestradiol''' ('''4-ME2''') is an [[endogenous]], [[natural product|naturally occurring]] [[methoxyl]]ated [[catechol estrogen]] and [[metabolite]] of [[estradiol]] that is formed by [[catechol O-methyltransferase]] via the [[chemical intermediate|intermediate]] [[4-hydroxyestradiol]].<ref name="HMDB">{{Cite web|url=http://www.hmdb.ca/metabolites/HMDB12782|title = Human Metabolome Database: Showing metabocard for 4-Methoxy-17beta-estradiol (HMDB0012782)}}</ref><ref name="Hemnes2015">{{cite book|author=Anna R. Hemnes|title=Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide|url=https://books.google.com/books?id=4So3CwAAQBAJ&pg=PA32|date=16 December 2015|publisher=Humana Press|isbn=978-3-319-23998-9|pages=32–}}</ref><ref name="LauritzenStudd2005">{{cite book|author1=Christian Lauritzen|author2=John W. W. Studd|title=Current Management of the Menopause|url=https://books.google.com/books?id=WD7S7677xUUC&pg=PA378|date=22 June 2005|publisher=CRC Press|isbn=978-0-203-48612-2|pages=378–379}}</ref> It has [[estrogen]]ic activity similarly to [[estrone]] and [[4-hydroxyestrone]].<ref name="pmid10865186">{{cite journal | vauthors = Bhavnani BR, Nisker JA, Martin J, Aletebi F, Watson L, Milne JK | title = Comparison of pharmacokinetics of a conjugated equine estrogen preparation (premarin) and a synthetic mixture of estrogens (C.E.S.) in postmenopausal women | journal = J. Soc. Gynecol. Investig. | volume = 7 | issue = 3 | pages = 175–83 | year = 2000 | pmid = 10865186 | doi = 10.1016/s1071-5576(00)00049-6}}</ref><br />
<br />
{{Selected biological properties of endogenous estrogens in rats}}<br />
<br />
==See also==<br />
* [[2-Methoxyestradiol]]<br />
* [[2-Methoxyestriol]]<br />
* [[2-Methoxyestrone]]<br />
* [[4-Methoxyestrone]]<br />
<br />
==References==<br />
{{Reflist}}<br />
<br />
==External links==<br />
* [http://www.hmdb.ca/metabolites/HMDB12782 Metabocard for 4-Methoxyestradiol - Human Metabolome Database]<br />
<br />
<br />
{{Endogenous steroids}}<br />
{{Estrogen receptor modulators}}<br />
<br />
{{DEFAULTSORT:Methoxyestradiol, 4-}}<br />
<br />
[[Category:Secondary alcohols]]<br />
[[Category:Estranes]]<br />
[[Category:Estrogens]]<br />
[[Category:Ethers]]<br />
[[Category:Human metabolites]]<br />
[[Category:Steroid hormones]]<br />
<br />
<br />
{{steroid-stub}}</div>
bsd>LegionMammal978