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Restored revision 1084544011 by Ffffrr (talk): Adding new uncited claims (facts and opinions)

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{{Short description|Chemical compound}}
{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (8''R'',9''S'',13''S'',14''S'')-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6''H''-cyclopenta[''a'']phenanthren-17-one
| image = Estrone methyl ether.svg
| width = 225px


| tradename =
| pregnancy_AU = 
| pregnancy_US = 
| pregnancy_category =
| legal_AU = 
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| class = [[Estrogen (medication)|Estrogen]]; [[Estrogen ether]]


| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =


| CAS_number_Ref =
| CAS_number = 1624-62-0
| CAS_supplemental = <br />1091-94-7
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 92895
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID =
| UNII = 4SMZ4A51IJ
| KEGG =
| ChEBI =
| ChEMBL = 1409077
| synonyms = Oestrone methyl ether; Estrone 3-methyl ether; 3-Methoxyestrone; 3-Methoxyestra-1,3,5(10)-trien-17-one


| C=19 | H=24 | O=2
| SMILES = C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OC
| StdInChI_Ref =
| StdInChI = 1S/C19H24O2/c1-19-10-9-15-14-6-4-13(21-2)11-12(14)3-5-16(15)17(19)7-8-18(19)20/h4,6,11,15-17H,3,5,7-10H2,1-2H3/t15-,16-,17+,19+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = BCWWDWHFBMPLFQ-VXNCWWDNSA-N
}}

'''Estrone methyl ether''', or '''estrone 3-methyl ether''', is a [[synthetic compound|synthetic]] [[estrogen (medication)|estrogen]] and [[estrogen ether]] – specifically, the C3 [[methyl group|methyl]] [[ether]] of [[estrone (medication)|estrone]] – which was never marketed.<ref name="Elks2014">{{cite book| vauthors = Elks J |title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA900|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=900–}}</ref><ref name="Milne2018">{{cite book| vauthors = Milne GW |title=Drugs: Synonyms and Properties: Synonyms and Properties|url=https://books.google.com/books?id=xUlaDwAAQBAJ&pg=PT1406|date=8 May 2018|publisher=Taylor & Francis|isbn=978-1-351-78989-9|pages=1406–}}</ref> It has been used to [[chemical synthesis|synthesize]] [[mestranol]] ([[ethinylestradiol]] 3-methyl ether).<ref name="Ravina2011">{{cite book| vauthors = Ravina E |title=The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs|url=https://books.google.com/books?id=iDNy0XxGqT8C&pg=PA190|date=11 January 2011|publisher=John Wiley & Sons|isbn=978-3-527-32669-3|pages=190–}}</ref>

==See also==
* [[List of estrogen esters#Ethers of steroidal estrogens|List of estrogen esters § Ethers of steroidal estrogens]]

==References==
{{Reflist}}

{{Estrogen receptor modulators}}

[[Category:Abandoned drugs]]
[[Category:Estranes]]
[[Category:Estrogen ethers]]
[[Category:Ketones]]
[[Category:Synthetic estrogens]]

{{Steroid-stub}}
{{Genito-urinary-drug-stub}}

Estrone methyl ether - 版の履歴

WikiSysop: 1版 をインポートしました

bsd>DMacks: Restored revision 1084544011 by Ffffrr (talk): Adding new uncited claims (facts and opinions)

WikiSysop: 1版をインポートしました