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Taleranol - 版の履歴
2026-04-12T09:13:04Z
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WikiSysop: 1版 をインポートしました
2025-03-18T10:34:17Z
<p>1版 をインポートしました</p>
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bsd>Artoria2e5: Restored revision 1123975874 by CharredShorthand (talk): Time for new glasses
2023-03-21T05:09:52Z
<p>Restored revision 1123975874 by <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%8A%95%E7%A8%BF%E8%A8%98%E9%8C%B2/CharredShorthand" title="特別:投稿記録/CharredShorthand">CharredShorthand</a> (<a href="/w/index.php?title=%E5%88%A9%E7%94%A8%E8%80%85%E3%83%BB%E3%83%88%E3%83%BC%E3%82%AF:CharredShorthand&action=edit&redlink=1" class="new" title="利用者・トーク:CharredShorthand (存在しないページ)">talk</a>): Time for new glasses</p>
<p><b>新規ページ</b></p><div>{{Short description|Chemical compound}}<br />
{{Drugbox<br />
| Verifiedfields = <br />
| Watchedfields = <br />
| verifiedrevid = <br />
| IUPAC_name = (7''S'',11''S'')-7,15,17-Trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one<br />
| image = Taleranol.svg<br />
| width = 250<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = <br />
| legal_UK = <br />
| legal_US = <br />
| legal_status = <br />
| routes_of_administration = <br />
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<!--Pharmacokinetic data--><br />
| bioavailability = <br />
| protein_bound = <br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
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<!-- Identifiers --><br />
| CAS_number_Ref = <br />
| CAS_number = 42422-68-4<br />
| CAS_supplemental = <br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| ATC_supplemental = <br />
| PubChem = 65434<br />
| IUPHAR_ligand = <br />
| DrugBank_Ref = <br />
| DrugBank = <br />
| ChemSpiderID_Ref = <br />
| ChemSpiderID = <br />
| UNII = HUN219N434<br />
| KEGG = <br />
| ChEBI = 35071<br />
| ChEMBL = 491510<br />
<br />
<!--Chemical data--><br />
| C=18 | H=26 | O=5<br />
| SMILES = C[C@H]1CCC[C@@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1<br />
| StdInChI_Ref = <br />
| StdInChI = 1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14-/m0/s1<br />
| StdInChIKey_Ref = <br />
| StdInChIKey = DWTTZBARDOXEAM-JSGCOSHPSA-N<br />
| synonyms = P-1560; Teranol; β-Zearalanol<br />
}}<br />
<br />
'''Taleranol''' ([[International Nonproprietary Name|INN]], [[United States Adopted Name|USAN]]) (developmental code name '''P-1560'''), or '''teranol''', also known as '''β-zearalanol''', is a [[synthetic compound|synthetic]], [[nonsteroidal]] [[estrogen]] of the [[resorcylic acid lactone]] group related to [[mycoestrogen]]s found in ''[[Fusarium|Fusarium spp]]'' which was never marketed.<ref name="Elks2014">{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA350|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=350–}}</ref><ref name="Yildiz2009">{{cite book| vauthors = Yildiz F |title=Advances in Food Biochemistry|url=https://books.google.com/books?id=orwY4Nd_t1wC&pg=PA233|date=16 December 2009|publisher=CRC Press|isbn=978-1-4200-0769-5|pages=233–}}</ref> It is the β [[epimer]] of [[zeranol]] (α-zearalanol) and is a major [[metabolite]] of zeranol but with less [[biological activity]].<ref name="Elks2014" /><ref name="YuWang2014">{{cite book| vauthors = Yu L, Wang S, Sun BG |title=Food Safety Chemistry: Toxicant Occurrence, Analysis and Mitigation|url=https://books.google.com/books?id=rs3MBQAAQBAJ&pg=PA240|date=28 October 2014|publisher=CRC Press|isbn=978-1-4665-9795-2|pages=240–}}</ref><ref name="Yildiz2009" /><br />
<br />
==See also==<br />
* [[α-Zearalenol]]<br />
* [[β-Zearalenol]]<br />
* [[Zearalanone]]<br />
* [[Zearalenone]]<br />
<br />
==References==<br />
{{Reflist}}<br />
<br />
<br />
{{Xenoestrogens}}<br />
{{Estrogen receptor modulators}}<br />
<br />
[[Category:Lactones]]<br />
[[Category:Mycoestrogens]]<br />
[[Category:Mycotoxins]]<br />
[[Category:Resorcinols]]<br />
<br />
<br />
{{genito-urinary-drug-stub}}</div>
bsd>Artoria2e5