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[[ | {| class="wikitable" | ||
[[ | |+Tyrosine Kinases | ||
[[ | !rowspan="7"| [[成長因子受容体]] | ||
[[ | ||[[ErbB|EGF receptor family]]||[[Epidermal growth factor receptor|EGFR]], [[HER2/neu|ERBB2]], [[ERBB3]], [[ERBB4]] | ||
|- | |||
|[[Insulin receptor]] family||[[Insulin-like growth factor 1 receptor|IGF1R]], [[Insulin receptor|INSR]], [[INSRR]] | |||
|- | |||
|[[RTK class III|PDGF receptor family]]|| [[Colony stimulating factor 1 receptor|CSF1R]], [[CD135|FLT3]], [[CD117|KIT]], [[platelet-derived growth factor receptor|PDGFR]] ([[PDGFRA]], [[PDGFRB]]) | |||
|- | |||
|[[Fibroblast growth factor receptor|FGF receptor]] family | |||
|[[Fibroblast growth factor receptor 1|FGFR1]], [[Fibroblast growth factor receptor 2|FGFR2]], [[Fibroblast growth factor receptor 3|FGFR3]], [[Fibroblast growth factor receptor 4|FGFR4]] | |||
|- | |||
| [[VEGF receptors]] family | |||
| list5 = | |||
* [[FLT1|VEGFR1]] | |||
* [[Kinase insert domain receptor|VEGFR2]] | |||
* [[VEGFR3]] | |||
* [[VEGFR4]] | |||
|- | |||
| [[C-Met|HGF receptor]] family | |||
| list6 = | |||
* [[C-Met|MET]] | |||
* [[MST1R|RON]] | |||
|- | |||
| [[Trk receptor]] family | |||
| list7 = | |||
* [[TrkA receptor|NTRK1]] | |||
* [[NTRK2]] | |||
* [[NTRK3]] | |||
|- | |||
!colspan="2"|[[Ephrin receptor|EPH receptor]] family | |||
|[[EPH receptor A1|EPHA1]], [[EPH receptor A2|EPHA2]], [[EPH receptor A3|EPHA3]], [[EPH receptor A4|EPHA4]], [[EPH receptor A5|EPHA5]], [[EPHA6]], [[EPHA7]], [[EPHA8]], [[EPH receptor B1|EPHB1]], [[EPH receptor B2|EPHB2]], [[EPHB3]], [[EPH receptor B4|EPHB4]], [[EPHB5]], [[EPHB6]], [[EPHX]] | |||
|- | |||
!colspan="2"|[[Leukocyte receptor tyrosine kinase|LTK receptor]] family | |||
| list9 = | |||
* [[Leukocyte receptor tyrosine kinase|LTK]] | |||
* [[Anaplastic lymphoma kinase|ALK]] | |||
|- | |||
!colspan="2"|[[Angiopoietin receptor|TIE receptor]] family | |||
| list10 = | |||
* [[TIE1|TIE]] | |||
* [[TEK tyrosine kinase|TEK]] | |||
|- | |||
!colspan="2"|[[Receptor tyrosine kinase-like orphan receptor|ROR receptor]] family | |||
| list11 = | |||
* [[ROR1]] | |||
* [[ROR2]] | |||
|- | |||
!colspan="2"| [[DDR1|DDR receptor]] family | |||
| list12 = | |||
* [[DDR1]] | |||
* [[Discoidin domain-containing receptor 2|DDR2]] | |||
|- | |||
!colspan="2"| [[PTK7|PTK7 receptor]] family | |||
| list13 = | |||
* [[PTK7]] | |||
|- | |||
!colspan="2"|[[related to receptor tyrosine kinase|RYK receptor]] family | |||
| list14 = | |||
* [[related to receptor tyrosine kinase|RYK]] | |||
|- | |||
!colspan="2"|[[MuSK protein|MuSK receptor]] family | |||
| list15 = | |||
* [[MuSK protein|MUSK]] | |||
|- | |||
!colspan="2"|[[ROS1 (gene)|ROS receptor]] family | |||
| list16 = | |||
* [[ROS1 (gene)|ROS1]] | |||
|- | |||
!colspan="2"|[[AATK|AATYK receptor]] family | |||
| list17 = | |||
* [[AATK|AATYK]] | |||
* [[LMTK2|AATYK2]] | |||
* [[AATYK3]] | |||
|- | |||
!colspan="2"| [[AXL receptor tyrosine kinase|AXL receptor]] family | |||
| list18 = | |||
* [[AXL receptor tyrosine kinase|AXL]] | |||
* [[MERTK|MER]] | |||
* [[TYRO3]] | |||
|- | |||
!colspan="2"|[[RET proto-oncogene|RET receptor]] family | |||
| list19 = | |||
* [[RET proto-oncogene|RET]] | |||
|- | |||
!colspan="2"|uncatagorised | |||
| | |||
* [[STYK1]] | |||
|- | |||
!colspan="3" |[[Non-receptor tyrosine kinase]]s (EC 2.7.10.2) | |||
|- | |||
|[[Abl gene|ABL]] family | |||
| list1 = | |||
* [[Abl gene|ABL1]] | |||
* [[ABL2|ARG]] | |||
|- | |||
|[[TNK2|ACK]] family | |||
| list2 = | |||
* [[TNK2|ACK1]] | |||
* [[TNK1]] | |||
|- | |||
|[[C-src tyrosine kinase|CSK]] family | |||
| list3 = | |||
* [[C-src tyrosine kinase|CSK]] | |||
* [[Megakaryocyte-associated tyrosine kinase|MATK]] | |||
|- | |||
| [[PTK2|FAK]] family | |||
| list4 = | |||
* [[PTK2|FAK]] | |||
* [[PTK2B|PYK2]] | |||
|- | |||
| [[Feline sarcoma oncogene|FES]] family | |||
| list5 = | |||
* [[Feline sarcoma oncogene|FES]] | |||
* [[FER (gene)|FER]] | |||
|- | |||
| [[Fyn-related kinase|FRK]] family | |||
| list6 = | |||
* [[Fyn-related kinase|FRK]] | |||
* [[PTK6|BRK]] | |||
* [[SRMS (gene)|SRMS]] | |||
|- | |||
|[[Janus kinase|JAK]] family | |||
| list7 = | |||
* [[Janus kinase 1|JAK1]] | |||
* [[Janus kinase 2|JAK2]] | |||
* [[Janus kinase 3|JAK3]] | |||
* [[Tyrosine kinase 2|TYK2]] | |||
|- | |||
| [[SRC-A]] family | |||
| list8 = | |||
* [[Src (gene)|SRC]] | |||
* [[FGR (gene)|FGR]] | |||
* [[FYN]] | |||
* [[YES1]] | |||
|- | |||
|[[SRC-B]] family | |||
| list9 = | |||
* [[Tyrosine-protein kinase BLK|BLK]] | |||
* [[HCK]] | |||
* [[Lck|LCK]] | |||
* [[LYN]] | |||
|- | |||
|[[TEC (gene)|TEC]] family | |||
| list10 = | |||
* [[TEC (gene)|TEC]] | |||
* [[BMX (gene)|BMX]] | |||
* [[Bruton's tyrosine kinase|BTK]] | |||
* [[ITK (gene)|ITK]] | |||
* [[TXK (gene)|TXK]] | |||
|- | |||
|[[Syk|SYK]] family | |||
| list11 = | |||
* [[Syk|SYK]] | |||
* [[ZAP-70|ZAP70]] | |||
} |
2013年4月12日 (金) 00:47時点における版
成長因子受容体 | EGF receptor family | EGFR, ERBB2, ERBB3, ERBB4 |
---|---|---|
Insulin receptor family | IGF1R, INSR, INSRR | |
PDGF receptor family | CSF1R, FLT3, KIT, PDGFR (PDGFRA, PDGFRB) | |
FGF receptor family | FGFR1, FGFR2, FGFR3, FGFR4 | |
VEGF receptors family | list5 = | |
HGF receptor family | list6 = | |
Trk receptor family | list7 = | |
EPH receptor family | EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6, EPHX | |
LTK receptor family | list9 = | |
TIE receptor family | list10 = | |
ROR receptor family | list11 = | |
DDR receptor family | list12 = | |
PTK7 receptor family | list13 = | |
RYK receptor family | list14 = | |
MuSK receptor family | list15 = | |
ROS receptor family | list16 = | |
AATYK receptor family | list17 = | |
AXL receptor family | list18 = | |
RET receptor family | list19 = | |
uncatagorised | ||
Non-receptor tyrosine kinases (EC 2.7.10.2) | ||
ABL family | list1 = | |
ACK family | list2 = | |
CSK family | list3 = | |
FAK family | list4 = | |
FES family | list5 = | |
FRK family | list6 = | |
JAK family | list7 = | |
SRC-A family | list8 = | |
SRC-B family | list9 = | |
TEC family | list10 = | |
SYK family | list11 =
} |