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(2人の利用者による、間の82版が非表示) | |||
1行目: | 1行目: | ||
[[ | {| class="wikitable" | ||
[[ | |+Tyrosine Kinases | ||
[[ | !rowspan="7"| [[成長因子受容体]] | ||
[[ | ||[[ErbB|EGF receptor family]]||[[Epidermal growth factor receptor|EGFR]], [[HER2/neu|ERBB2]], [[ERBB3]], [[ERBB4]] | ||
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|[[Insulin receptor]] family||[[Insulin-like growth factor 1 receptor|IGF1R]], [[Insulin receptor|INSR]], [[INSRR]] | |||
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|[[RTK class III|PDGF receptor family]]|| [[Colony stimulating factor 1 receptor|CSF1R]], [[CD135|FLT3]], [[CD117|KIT]], [[platelet-derived growth factor receptor|PDGFR]] ([[PDGFRA]], [[PDGFRB]]) | |||
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|[[Fibroblast growth factor receptor|FGF receptor]] family | |||
|[[Fibroblast growth factor receptor 1|FGFR1]], [[Fibroblast growth factor receptor 2|FGFR2]], [[Fibroblast growth factor receptor 3|FGFR3]], [[Fibroblast growth factor receptor 4|FGFR4]] | |||
|- | |||
| [[VEGF receptors]] family | |||
| [[FLT1|VEGFR1]], [[Kinase insert domain receptor|VEGFR2]], [[VEGFR3]], [[VEGFR4]] | |||
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| [[C-Met|HGF receptor]] family | |||
|[[C-Met|MET]], [[MST1R|RON]] | |||
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| [[Trk receptor]] family | |||
|[[TrkA receptor|NTRK1]], [[NTRK2]], [[NTRK3]] | |||
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!colspan="2"|[[Ephrin receptor|EPH receptor]] family | |||
|[[EPH receptor A1|EPHA1]], [[EPH receptor A2|EPHA2]], [[EPH receptor A3|EPHA3]], [[EPH receptor A4|EPHA4]], [[EPH receptor A5|EPHA5]], [[EPHA6]], [[EPHA7]], [[EPHA8]], [[EPH receptor B1|EPHB1]], [[EPH receptor B2|EPHB2]], [[EPHB3]], [[EPH receptor B4|EPHB4]], [[EPHB5]], [[EPHB6]], [[EPHX]] | |||
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!colspan="2"|[[Leukocyte receptor tyrosine kinase|LTK receptor]] family | |||
|, [[Leukocyte receptor tyrosine kinase|LTK]], [[Anaplastic lymphoma kinase|ALK]] | |||
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!colspan="2"|[[Angiopoietin receptor|TIE receptor]] family | |||
|[[TIE1|TIE]], [[TEK tyrosine kinase|TEK]] | |||
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!colspan="2"|[[Receptor tyrosine kinase-like orphan receptor|ROR receptor]] family | |||
|[[ROR1]], [[ROR2]] | |||
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!colspan="2"| [[DDR1|DDR receptor]] family | |||
| list12 = [[DDR1]], [[Discoidin domain-containing receptor 2|DDR2]] | |||
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!colspan="2"| [[PTK7|PTK7 receptor]] family | |||
|[[PTK7]] | |||
|- | |||
!colspan="2"|[[related to receptor tyrosine kinase|RYK receptor]] family | |||
|[[related to receptor tyrosine kinase|RYK]] | |||
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!colspan="2"|[[MuSK protein|MuSK receptor]] family | |||
|[[MuSK protein|MUSK]] | |||
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!colspan="2"|[[ROS1 (gene)|ROS receptor]] family | |||
|[[ROS1 (gene)|ROS1]] | |||
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!colspan="2"|[[AATK|AATYK receptor]] family | |||
|[[AATK|AATYK]], [[LMTK2|AATYK2]], [[AATYK3]] | |||
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!colspan="2"| [[AXL receptor tyrosine kinase|AXL receptor]] family | |||
| [[AXL receptor tyrosine kinase|AXL]], [[MERTK|MER]], [[TYRO3]] | |||
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!colspan="2"|[[RET proto-oncogene|RET receptor]] family | |||
|[[RET proto-oncogene|RET]] | |||
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!colspan="2"|uncatagorised | |||
|[[STYK1]] | |||
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!colspan="3" |[[Non-receptor tyrosine kinase]]s (EC 2.7.10.2) | |||
|- | |||
|[[Abl gene|ABL]] family | |||
| [[Abl gene|ABL1]], [[ABL2|ARG]] | |||
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|[[TNK2|ACK]] family | |||
|[[TNK2|ACK1]], [[TNK1]] | |||
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|[[C-src tyrosine kinase|CSK]] family | |||
| [[C-src tyrosine kinase|CSK]], [[Megakaryocyte-associated tyrosine kinase|MATK]] | |||
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| [[PTK2|FAK]] family | |||
| [[PTK2|FAK]], [[PTK2B|PYK2]] | |||
|- | |||
| [[Feline sarcoma oncogene|FES]] family | |||
|[[Feline sarcoma oncogene|FES]], [[FER (gene)|FER]] | |||
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| [[Fyn-related kinase|FRK]] family | |||
| [[Fyn-related kinase|FRK]], [[PTK6|BRK]], [[SRMS (gene)|SRMS]] | |||
|- | |||
|[[Janus kinase|JAK]] family | |||
|[[Janus kinase 1|JAK1]], [[Janus kinase 2|JAK2]], [[Janus kinase 3|JAK3]], [[Tyrosine kinase 2|TYK2]] | |||
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|[[SRC-A]] family | |||
|[[Src (gene)|SRC]], [[FGR (gene)|FGR]], [[FYN]], [[YES1]] | |||
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|[[SRC-B]] family | |||
|[[Tyrosine-protein kinase BLK|BLK]], [[HCK]], [[Lck|LCK]] | |||
, [[LYN]] | |||
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|[[TEC (gene)|TEC]] family | |||
|[[TEC (gene)|TEC]], [[BMX (gene)|BMX]], [[Bruton's tyrosine kinase|BTK]], [[ITK (gene)|ITK]], [[TXK (gene)|TXK]] | |||
|- | |||
|[[Syk|SYK]] family | |||
|[[Syk|SYK]], [[ZAP-70|ZAP70]] | |||
} |