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Förster共鳴エネルギー移動 (ソースを閲覧)

2013年12月28日 (土) 19:29時点における版

176 バイト除去 、 2013年12月28日 (土)
細
→‎生体膜上の小分子
細編集の要約なし
166行目: 166行目:
|[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 ||D || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref><ref><pubmed>23801067</pubmed></ref>   
|[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 ||D || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref><ref><pubmed>23801067</pubmed></ref>   
|-
|-
|[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || 2, D || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
|[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || B, D || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
|-
|-
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || D || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || D || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
|-
|-
|[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || その他、3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
|[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || その他 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
|-
|-
|[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
|[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || D || <ref><pubmed>19720993</pubmed></ref>
|-
|-
|[[エストロゲン]] ||SCCoR|| 2004 || D || <ref><pubmed>15080726</pubmed></ref>
|[[エストロゲン]] ||SCCoR|| 2004 || D || <ref><pubmed>15080726</pubmed></ref>
|-
|-
|[[アンドロゲン]] ||Ficaro|| 2006 || D || <ref><pubmed>16555356</pubmed></ref>
|[[アンドロゲン]] ||Ficaro|| 2006 || E || <ref><pubmed>16555356</pubmed></ref>
|-
|-
|[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || B, E || <ref><pubmed>15163683</pubmed></ref><ref><pubmed>17897691</pubmed></ref>
|[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || B, E || <ref><pubmed>15163683</pubmed></ref><ref><pubmed>17897691</pubmed></ref>
|-
|-
|[[神経成長因子]] ||ECaus|| 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
|[[神経成長因子]] ||ECaus|| 2008 || F|| <ref><pubmed>18510313</pubmed></ref>
|-
|-
|[[核内受容体]] ||conpro|| 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
|[[核内受容体]] ||conpro|| 2007 || E || <ref><pubmed>17387660</pubmed></ref>
|-
|-
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || F || <ref><pubmed>17105262</pubmed></ref>
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || F || <ref><pubmed>17105262</pubmed></ref>
192行目: 192行目:
|[[グルタミン酸]] ||FLIPE|| 2005 || D || <ref><pubmed>15939876</pubmed></ref>
|[[グルタミン酸]] ||FLIPE|| 2005 || D || <ref><pubmed>15939876</pubmed></ref>
|-
|-
|[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
|[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || D || <ref><pubmed>19718032</pubmed></ref>
|-
|-
|[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || その他 || <ref><pubmed>11055428</pubmed></ref>
|[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || その他 || <ref><pubmed>11055428</pubmed></ref>
220行目: 220行目:
| [[c-Raf]] ||Prin-cRaf|| 2005 || D || <ref><pubmed>15711535</pubmed></ref>
| [[c-Raf]] ||Prin-cRaf|| 2005 || D || <ref><pubmed>15711535</pubmed></ref>
|-
|-
| [[P21 protein-activated kinase 1]] ([[PAK1]]) ||Pakabi|| 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
| [[P21 protein-activated kinase 1]] ([[PAK1]]) ||Pakabi|| 2009 || D || <ref><pubmed>19574218</pubmed></ref>
|-
|-
| [[B-raf]] ||Prin-Braf|| 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
| [[B-raf]] ||Prin-Braf|| 2006 || D || <ref><pubmed>16858395</pubmed></ref>
|-
|-
| [[Zeta-chain-associated protein kinase 70]] ([[ZAP-70]]) ||ROZA|| 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
| [[Zeta-chain-associated protein kinase 70]] ([[ZAP-70]]) ||ROZA|| 2008 || F || <ref><pubmed>18231606</pubmed></ref>
|-
|-
| [[Akt]] ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref name=ref17407381><pubmed> 17407381</pubmed></ref>
| [[Akt]] ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || F || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref name=ref17407381><pubmed> 17407381</pubmed></ref>
|-
|-
| [[細胞外シグナル調節キナーゼ]] ([[Extracellular signal-regulated kinases]], [[ERK]]) ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
| [[細胞外シグナル調節キナーゼ]] ([[Extracellular signal-regulated kinases]], [[ERK]]) ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || D, F || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
|-
|-
| [[インシュリン受容体]] ||Phocus|| 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
| [[インシュリン受容体]] ||Phocus|| 2002 || F || <ref><pubmed>11875431</pubmed></ref>
|-
|-
| [[上皮成長因子受容体]] ([[EGFR]]) || ||2001 || 3-3 || <ref name=ref11752449 />
| [[上皮成長因子受容体]] ([[EGFR]]) || ||2001 || F || <ref name=ref11752449 />
|-
|-
| [[Ataxia telangiectasia mutated]] ([[ATM]]) || || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
| [[Ataxia telangiectasia mutated]] ([[ATM]]) || || 2007 || F || <ref><pubmed>17428747</pubmed></ref>
|-
|-
|[[オーロラBキナーゼ]] || || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
|[[オーロラBキナーゼ]] || || 2008 || F || <ref><pubmed>18463638</pubmed></ref>
|-
|-
| [[サイクリンB1]]-[[サイクリン依存性キナーゼ1]] || || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
| [[サイクリンB1]]-[[サイクリン依存性キナーゼ1]] || || 2010 || F || <ref><pubmed>20412769</pubmed></ref>
|-
|-
| [[ミオシン軽鎖キナーゼ]] ||MLCK-FIP || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
| [[ミオシン軽鎖キナーゼ]] ||MLCK-FIP || 2002 || D || <ref><pubmed>11815633</pubmed></ref>
|-
|-
| [[c-Jun N端末キナーゼ]] ([[JNK]]) ||JNKAR1, JUNKAR1EV || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
| [[c-Jun N端末キナーゼ]] ([[JNK]]) ||JNKAR1, JUNKAR1EV || 2010, 2011 || F || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
|-
|-
| [[リボソームS6キナーゼ]] ([[RSK]], [[S6K]]) ||Eevee-RSK, Eevee-S6K|| 2011 || 3-3 || <ref name=ref21976697></ref>
| [[リボソームS6キナーゼ]] ([[RSK]], [[S6K]]) ||Eevee-RSK, Eevee-S6K|| 2011 || F || <ref name=ref21976697></ref>
|-
|-
| [[接着斑キナーゼ]] ([[Focal Adhesion Kinase]], [[FAK]]) ||CYFAK413, FERM-sensor|| 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
| [[接着斑キナーゼ]] ([[Focal Adhesion Kinase]], [[FAK]]) ||CYFAK413, FERM-sensor|| 2008, 2009 || B, D || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
|-
|-
| [[Polo様キナーゼ1]] ([[polo-like kinase1]], [[PLK1]]) || || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
| [[Polo様キナーゼ1]] ([[polo-like kinase1]], [[PLK1]]) || || 2008 || F || <ref><pubmed>18615013</pubmed></ref>
|-
|-
| [[ストレス活性化プロテインキナーゼ3]] ([[Stress-Activated Protein Kinase Kinase Kinase]], [[stress-activated protein kinase 3]], [[SAP3K]]) || || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
| [[ストレス活性化プロテインキナーゼ3]] ([[Stress-Activated Protein Kinase Kinase Kinase]], [[stress-activated protein kinase 3]], [[SAP3K]]) || || 2009 || F || <ref><pubmed>19737916</pubmed></ref>
|-
|-
| [[細胞死関連タンパク質キナーゼ]] ([[death associated protein kinase 1]], [[DAPK1]]) ||DAPK1(334)-F40|| 2011 || 3-1 || <ref name=ref21506563 />
| [[細胞死関連タンパク質キナーゼ]] ([[death associated protein kinase 1]], [[DAPK1]]) ||DAPK1(334)-F40|| 2011 || D || <ref name=ref21506563 />
|-
|-
| [[ホスファターゼ]] || [[カルシニューリン]] ||CaNAR1|| 2008, 2013 || 3-1 || <ref name=ref23602566 /><ref><pubmed> 18493642</pubmed></ref>
| [[ホスファターゼ]] || [[カルシニューリン]] ||CaNAR1|| 2008, 2013 || D || <ref name=ref23602566 /><ref><pubmed> 18493642</pubmed></ref>
|-
|-
|rowspan="8" | [[低分子量Gタンパク質]] || [[Ras]] ||Raichu-Ras, Fras|| 2001, 2006 || B, E || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
|rowspan="8" | [[低分子量Gタンパク質]] || [[Ras]] ||Raichu-Ras, Fras|| 2001, 2006 || B, E || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
268行目: 268行目:
| [[Cdc42]] ||Raichu-cdc42|| 2004, 2011 || B, E || <ref name=ref14570905 /><ref name=ref21423166 />
| [[Cdc42]] ||Raichu-cdc42|| 2004, 2011 || B, E || <ref name=ref14570905 /><ref name=ref21423166 />
|-
|-
| [[Ral]] ||Raichu-Ral|| 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
| [[Ral]] ||Raichu-Ral|| 2004 || E || <ref><pubmed>15034142</pubmed></ref>
|-
|-
| [[TC10]] ||Raichu-TC10|| 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
| [[TC10]] ||Raichu-TC10|| 2006 || E || <ref><pubmed>16950130</pubmed></ref>
|-
|-
|rowspan="6" | [[シグナル伝達]] || [[RCC1]] ([[Ran]]に対する[[GDP, GTP交換因子]]) ||CFP-RCC1-YFP|| 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
|rowspan="6" | [[シグナル伝達]] || [[RCC1]]||CFP-RCC1-YFP|| 2008 || D || <ref><pubmed>18762580</pubmed></ref>
|-
|-
| [[CrkII]][[リン酸化]] ||Picchu|| 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
| [[CrkII]][[リン酸化]] ||Picchu|| 2001 || F || <ref><pubmed>11406630</pubmed></ref>
|-
|-
| [[Wiskott-Aldrich syndrome-like]] ([[WASL]], [[neuronal Wiskott–Aldrich syndrome protein]], [[N-WASP]]) ||Stinger|| 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
| [[neuronal Wiskott–Aldrich syndrome protein]] ([[N-WASP]]) ||Stinger|| 2004 || D || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
|-
|-
| [[アドレナリン受容体]] ||α<sub>2A</sub>[[AR]]-cam|| 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref>
| [[アドレナリン受容体]] ||α<sub>2A</sub>[[AR]]-cam|| 2003 || D|| <ref name=ref12808462><pubmed>12808462</pubmed></ref>
|-
|-
| [[副甲状腺ホルモン受容体]] ||PTHR-cam|| 2003 || 3-1 || <ref name=ref12808462 />
| [[副甲状腺ホルモン受容体]] ||PTHR-cam|| 2003 || D || <ref name=ref12808462 />
|-
|-
| [[細胞膜]][[カルシウムポンプ]] ||BFP-PMCA-GFP|| 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
| [[細胞膜]][[カルシウムポンプ]] ||BFP-PMCA-GFP|| 2007 || D || <ref><pubmed>17901055</pubmed></ref>
|-
|-
| [[アセチル化]] || [[ヒストン]]アセチル化 ||Histac|| 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
| [[アセチル化]] || [[ヒストン]]アセチル化 ||Histac|| 2004, 2009 || F|| <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
|-
|-
|rowspan="6" | [[脂質]] || [[ホスファチジルイノシトール-3,4,5-三リン酸]] ([[PIP3|PIP<sub>3</sub>]]) ||Fllip, FLIMPA|| 2003 || G || <ref><pubmed>14528311</pubmed></ref>
|rowspan="6" | [[脂質]] || [[ホスファチジルイノシトール-3,4,5-三リン酸]] ([[PIP3|PIP<sub>3</sub>]]) ||Fllip, FLIMPA|| 2003 || G || <ref><pubmed>14528311</pubmed></ref>
300行目: 300行目:
|rowspan="6" | タンパク質相互作用 || [[アクチン]] || ||2004, 2008 || C || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
|rowspan="6" | タンパク質相互作用 || [[アクチン]] || ||2004, 2008 || C || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
|-
|-
| [[3-ホスホイノシチド依存性プロテインキナーゼ1]]（[[phosphoinositide-dependent protein kinase 1]], [[PDK1]])-[[タンパク質キナーゼB]] ([[protein kinase B]], [[PKB]], [[Akt]])相互作用 || ||2007 || 2 || <ref name=ref17407381 />
| [[3-ホスホイノシチド依存性プロテインキナーゼ1]]（[[phosphoinositide-dependent protein kinase 1]], [[PDK1]])-[[タンパク質キナーゼB]] ([[protein kinase B]], [[PKB]], [[Akt]])相互作用 || ||2007 || B || <ref name=ref17407381 />
|-
|-
| [[タンパク質チロシン脱リン酸化酵素1B]] ([[protein tyrosine phosphatase 1B]], [[PTP 1B]])-[[受容体型チロシンキナーゼ]] ([[receptor tyrosine kinase]]s, [[RTK]]s)相互作用 || || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
| [[タンパク質チロシン脱リン酸化酵素1B]] ([[protein tyrosine phosphatase 1B]], [[PTP 1B]])-[[受容体型チロシンキナーゼ]] ([[receptor tyrosine kinase]]s, [[RTK]]s)相互作用 || || 2002 || B || <ref><pubmed>11872838</pubmed></ref>
|-
|-
| [[乳癌耐性タンパク質]] ([[breast cancer resistance protein]], [[BCRP]])/[[ATP結合カセット輸送体]] ([[ATP-binding cassette sub-family G member]], [[ABCG]])相互作用 || ||2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
| [[乳癌耐性タンパク質]] ([[breast cancer resistance protein]], [[BCRP]])/[[ATP結合カセット輸送体]] ([[ATP-binding cassette sub-family G member]], [[ABCG]])相互作用 || ||2010 || B || <ref><pubmed>20622991</pubmed></ref>
|-
|-
| [[コフィリン]]-[[アクチン]]相互作用 || ||2008 || B || <ref><pubmed>17993279</pubmed></ref>
| [[コフィリン]]-[[アクチン]]相互作用 || ||2008 || B || <ref><pubmed>17993279</pubmed></ref>
|-
|-
| [[第10染色体ホスファターゼ・テンシン・ホモログ]] ([[Phosphatase and tensin homolog deleted from chromosome 10]], [[PTEN]])-[[ミオシンV]]相互作用 || ||2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
| [[第10染色体ホスファターゼ・テンシン・ホモログ]] ([[Phosphatase and tensin homolog deleted from chromosome 10]], [[PTEN]])-[[ミオシンV]]相互作用 || ||2009 || B || <ref><pubmed>19767745</pubmed></ref>
|-
|-
|rowspan="8" | [[プロテアーゼ]] || [[カスパーゼ-3]] ||EGFP-DEVD-EBFP|| 1998 || A || <ref><pubmed>9518501</pubmed></ref>
|rowspan="8" | [[プロテアーゼ]] || [[カスパーゼ-3]] ||EGFP-DEVD-EBFP|| 1998 || A || <ref><pubmed>9518501</pubmed></ref>
324行目: 324行目:
|[[カルパイン]]活性||pYSCS|| 2000 || A || <ref><pubmed>10688895</pubmed></ref>
|[[カルパイン]]活性||pYSCS|| 2000 || A || <ref><pubmed>10688895</pubmed></ref>
|-
|-
| [[プレセニリン]] ||GFP-PSI-RFP|| 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
| [[プレセニリン]] ||GFP-PSI-RFP|| 2009 || A || <ref><pubmed>19924286</pubmed></ref>
|-
|-
|rowspan="5" | その他 ||細胞膜張力センサー ||stFRET|| 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
|rowspan="5" | その他 ||細胞膜張力センサー ||stFRET|| 2008 || D || <ref><pubmed>18479457</pubmed></ref>
|-
|-
| [[膜電位]] ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || D || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref><ref><pubmed> 23868559</pubmed></ref>
| [[膜電位]] ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || D || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref><ref><pubmed> 23868559</pubmed></ref>
|-
|-
| [[ミオシンII]] ||GSldCB|| 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
| [[ミオシンII]] ||GSldCB|| 1998, 2006 || D || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
|-
|-
| [[wj:ヒト免疫不全ウイルス|ヒト免疫不全ウイルス]]Revタンパク質 ||YRGnC-11ad|| 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
| [[wj:ヒト免疫不全ウイルス|ヒト免疫不全ウイルス]]Revタンパク質 ||YRGnC-11ad|| 2005 || E || <ref><pubmed>16013840</pubmed></ref>
|-
|-
|| [[wj:酸化還元|酸化還元]] ||Redoxfluor, Gaskins|| 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|| [[wj:酸化還元|酸化還元]] ||Redoxfluor, Gaskins|| 2010, 2011 || D || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|}
|}


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