テンプレート:PBB/93986

Forkhead box P2
PDB rendering based on 2a07.
Available structures PDB 2A07​, 2AS5​
Identifiers
Symbols	FOXP2; CAGH44; SPCH1; TNRC10
External IDs	OMIM: 605317 MGI: 2148705 HomoloGene: 33482 GeneCards: FOXP2 Gene
Gene Ontology Molecular function • DNA binding • chromatin binding • double-stranded DNA binding • sequence-specific DNA binding transcription factor activity • RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity • transcription factor binding • DNA binding, bending • protein homodimerization activity • sequence-specific DNA binding • metal ion binding • protein heterodimerization activity Cellular component • transcription factor complex • cytoplasm Biological process • positive regulation of mesenchymal cell proliferation • pattern specification process • skeletal muscle tissue development • embryo development • post-embryonic development • cerebellum development • caudate nucleus development • putamen development • cerebral cortex development • growth • vocal learning • camera-type eye development • negative regulation of transcription, DNA-dependent • lung alveolus development • smooth muscle tissue development • regulation of sequence-specific DNA binding transcription factor activity • righting reflex • positive regulation of epithelial cell proliferation involved in lung morphogenesis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	93986	114142
Ensembl	ENSG00000128573	ENSMUSG00000029563
UniProt	O15409	P58463
RefSeq (mRNA)	NM_001172766	NM_053242
RefSeq (protein)	NP_001166237	NP_444472
Location (UCSC)	Chr 7: 113.73 – 114.33 Mb	Chr 6: 14.9 – 15.44 Mb
PubMed search	[1]	[2]