テンプレート:PBB/136

Adenosine A2b receptor
Identifiers
Symbols	ADORA2B; ADORA2
External IDs	OMIM: 600446 MGI: 99403 HomoloGene: 20167 IUPHAR: A2B GeneCards: ADORA2B Gene
Gene Ontology Molecular function • G-protein coupled adenosine receptor activity Cellular component • intracellular • plasma membrane • integral component of plasma membrane Biological process • activation of MAPK activity • adenosine receptor signaling pathway • positive regulation of chronic inflammatory response to non-antigenic stimulus • cellular defense response • G-protein coupled receptor signaling pathway • adenylate cyclase-activating G-protein coupled receptor signaling pathway • activation of adenylate cyclase activity • JNK cascade • excretion • positive regulation of vascular endothelial growth factor production • positive regulation of guanylate cyclase activity • cellular response to extracellular stimulus • positive regulation of chemokine production • positive regulation of interleukin-6 production • positive regulation of mast cell degranulation • relaxation of vascular smooth muscle Sources: Amigo / QuickGO
RNA expression pattern
ファイル:PBB GE ADORA2B 205891 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	136	11541
Ensembl	ENSG00000170425	ENSMUSG00000018500
UniProt	P29275	Q60614
RefSeq (mRNA)	NM_000676	NM_007413
RefSeq (protein)	NP_000667	NP_031439
Location (UCSC)	Chr 17: 15.94 – 15.98 Mb	Chr 11: 62.25 – 62.27 Mb
PubMed search	[1]	[2]