「17α-Dihydroequilin」の版間の差分

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2025年3月18日 (火) 19:26時点における最新版

17α-Dihydroequilin
ファイル:17α Dihydroequilin.svg
Systematic (IUPAC) name
(9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol
Clinical data
Pregnancy cat. ?
Legal status ?
Routes By mouth
Identifiers
CAS number 651-55-8
ATC code G03CA57
PubChem CID 9547222
ChemSpider 7826162
UNII 48P73794OJ
Synonyms α-Dihydroequilin; 7-Dehydro-17α-estradiol; Estra-1,3,5(10),7-tetraen-3,17α-diol
Chemical data
Formula C18H22O2 

17α-Dihydroequilin, or α-dihydroequilin, also known as 7-dehydro-17α-estradiol, as well as estra-1,3,5(10),7-tetraene-3,17α-diol, is a naturally occurring steroidal estrogen found in horses which is closely related to equilin, equilenin, and 17α-estradiol.[1][2] The compound, as the 3-sulfate ester sodium salt, is present in conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares, and is the third highest quantity constituent in the formulation (13.8%).[1] The compound has been studied clinically.[3]

See also

References

  1. 以下の位置に戻る: 1.0 1.1 Fritz MA, Speroff L (28 March 2012). Clinical Gynecologic Endocrinology and Infertility. Lippincott Williams & Wilkins. pp. 751–. ISBN 978-1-4511-4847-3.
  2. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; World Health Organization; International Agency for Research on Cancer (2007). Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. pp. 378–. ISBN 978-92-832-1291-1.
  3. Wilcox JG, Stanczyk FZ, Morris RS, Gentzschein E, Lobo RA (November 1996). "Biologic effects of 17 alpha-dihydroequilin sulfate". Fertility and Sterility. 66 (5): 748–52. doi:10.1016/S0015-0282(16)58629-4. PMID 8893678.

テンプレート:Genito-urinary-drug-stub テンプレート:Steroid-stub