「Triphenylbromoethylene」の版間の差分
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2025年3月18日 (火) 19:35時点における最新版
| ファイル:Triphenylbromoethylene.png | |
|---|---|
| Systematic (IUPAC) name | |
| (1-bromo-2,2-diphenylethenyl)benzene | |
| Clinical data | |
| Trade names | Bromylene, Eitriphin, Oestronyl, Prostilban, Tribenorm |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 1607-57-4 |
| ATC code | ? |
| PubChem | CID 15354 |
| ChemSpider | 14615 |
| UNII | MRW5MKO6LZ |
| Synonyms | TPBE; Tribromophenylethylene; Bromotriphenylethylene; Phenylstilbene bromide; Fenbrostilbenum |
| Chemical data | |
| Formula | C20H15Br |
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Triphenylbromoethylene (TPBE; brand names Bromylene, Eitriphin, Oestronyl, Prostilban, Tribenorm), also known as bromotriphenylethylene or as phenylstilbene bromide, is a synthetic nonsteroidal estrogen of the triphenylethylene group that was marketed in the 1940s similarly to the closely related estrogen triphenylchloroethylene.[1][2]
A diethoxylated derivative of triphenylbromoethylene, estrobin (DBE), is also an estrogen, but, in contrast, was never marketed.[3] An ethylated derivative of triphenylbromoethylene, broparestrol (BDPE), is a selective estrogen receptor modulator (SERM) that has been marketed.[4][5]
See also
References
- ↑ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 1861. ISBN 978-3-527-30247-5.
C20H15Br. 1607-57-4. Bromotriphenylethene = Triphenylbromoethylene = Phenylstilbene bromide = 1,1',1"-(1-Bromo-1-ethenyl-2-yli- dene)tris[benzene] (•) S Bromylene, Fenbrostilbenum, Oestronyl, Phenylstilbene bromide, Prostilban, Tribenorm U Synthetic estrogen
- ↑ Paterson E, Gilbert CW (May 1949). "Metabolism of the oestrogen triphenylbromoethylene". Nature. 163 (4151): 801–802. Bibcode:1949Natur.163..801P. doi:10.1038/163801a0. PMID 18128458. S2CID 13052481.
- ↑ Emmens CW (22 October 2013). Hormone Assay. Elsevier Science. pp. 394–. ISBN 978-1-4832-7286-3.
- ↑ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 183–. ISBN 978-1-4757-2085-3.
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 139–. ISBN 978-3-88763-075-1.
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