「Α-Zearalenol」の版間の差分
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2025年3月18日 (火) 19:35時点における最新版
| ファイル:Alpha Zearalenol.svg | |
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| Systematic (IUPAC) name | |
| (2E,7R,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraen-13-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 36455-72-8 |
| ATC code | ? |
| PubChem | CID 5284645 |
| ChemSpider | 4447689 |
| UNII | 59D4EVJ5KC |
| KEGG | C14750 |
| ChEBI | CHEBI:35065 |
| ChEMBL | CHEMBL371463 |
| Synonyms | alpha-Zearalenol; trans-Zearalenol; 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone |
| Chemical data | |
| Formula | C18H24O5 |
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α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the α-epimer of β-zearalenol.[2] Along with β-zearalenol, it is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively low proportion of β-zearalenol is metabolized from zearalenone compared to α-zearalenol in humans.[3] α-Zearalenol is about three to four times more potent as an estrogen relative to zearalenone.[1]
See also
- Taleranol (β-zearalanol)
- Zeranol (α-zearalanol)
- Zearalanone
References
- ↑ 以下の位置に戻る: 1.0 1.1 Chelkowski J (28 June 2014). Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. pp. 85–. ISBN 978-1-4832-9785-9.
- ↑ 以下の位置に戻る: 2.0 2.1 Magan N, Olsen M (2004). Mycotoxins in Food: Detection and Control. Woodhead Publishing. pp. 356–. ISBN 978-1-85573-733-4.
- ↑ 以下の位置に戻る: 3.0 3.1 Eriksen GS (1998). Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. pp. 61–. ISBN 978-92-893-0149-7.
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