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PBB/5649
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2013年9月5日 (木) 00:05時点における
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(ページの作成:「{{GNF_Protein_box | Name = Reelin | image = 2DDU.pdb | image_source = Crystallographic structure of the third reelin repeat domain based on {{PDB|2ddu}}<ref name="1685...」)
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Reelin
Crystallographic structure of the third reelin repeat domain based on
PDB
:
2ddu
引用エラー: 無効な
<ref>
タグです。名前に単なる整数は使用できません。説明的なものにしてください
.
Available structures
PDB
2ddu
,
2e26
Identifiers
Symbols
RELN
; LIS2; PRO1598; RL
External IDs
OMIM
:
600514
MGI
:
103022
HomoloGene
:
3699
GeneCards
:
RELN Gene
EC number
3.4.21.-
Gene Ontology
Molecular function
•
protein serine/threonine/tyrosine kinase activity
•
serine-type peptidase activity
•
metal ion binding
•
lipoprotein particle receptor binding
•
very-low-density lipoprotein particle receptor binding
Cellular component
•
proteinaceous extracellular matrix
•
extracellular space
•
cytoplasm
•
dendrite
Biological process
•
cell morphogenesis involved in differentiation
•
neuron migration
•
proteolysis
•
cell adhesion
•
axon guidance
•
central nervous system development
•
brain development
•
long-term memory
•
associative learning
•
glial cell differentiation
•
positive regulation of neuron projection development
•
positive regulation of phosphatidylinositol 3-kinase cascade
•
dendrite development
•
peptidyl-tyrosine phosphorylation
•
spinal cord patterning
•
ventral spinal cord development
•
hippocampus development
•
cerebral cortex tangential migration
•
positive regulation of TOR signaling cascade
•
positive regulation of CREB transcription factor activity
•
reelin-mediated signaling pathway
•
positive regulation of protein kinase activity
•
response to pain
•
positive regulation of peptidyl-tyrosine phosphorylation
•
regulation of behavior
•
regulation of synaptic transmission
•
positive regulation of small GTPase mediated signal transduction
•
positive regulation of synaptic transmission, glutamatergic
•
positive regulation of dendritic spine morphogenesis
•
positive regulation of protein tyrosine kinase activity
•
positive regulation of synapse maturation
•
N-methyl-D-aspartate receptor clustering
•
postsynaptic density protein 95 clustering
•
receptor localization to synapse
•
positive regulation of long-term synaptic potentiation
•
regulation of N-methyl-D-aspartate selective glutamate receptor activity
•
positive regulation of excitatory postsynaptic membrane potential
•
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
5649
19699
Ensembl
ENSG00000189056
ENSMUSG00000042453
UniProt
P78509
Q60841
RefSeq (mRNA)
NM_005045
NM_011261
RefSeq (protein)
NP_005036
NP_035391
Location (UCSC)
Chr 7:
103.11 – 103.63 Mb
Chr 5:
21.88 – 22.34 Mb
PubMed
search
[1]
[2]
v
t
e
References
These references will appear in the article, but this list appears only on this page.