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テンプレート
:
PBB/4804
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テンプレート:PBB
2012年12月6日 (木) 00:17時点における
WikiSysop
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による版
(ページの作成:「{{GNF_Protein_box | Name = Nerve growth factor receptor | image = Protein_NGFR_PDB_1sg1.png | image_source =
PDB
rendering based on 1sg1. | PDB =...」)
(差分) ← 古い版 | 最新版 (差分) | 新しい版 → (差分)
Nerve growth factor receptor
PDB
rendering based on 1sg1.
Available structures
PDB
3EWV
Identifiers
Symbols
NGFR
; CD271; Gp80-LNGFR; TNFRSF16; p75(NTR); p75NTR
External IDs
OMIM
:
162010
MGI
:
97323
HomoloGene
:
1877
GeneCards
:
NGFR Gene
Gene Ontology
Molecular function
•
signal transducer activity
•
receptor activity
•
transmembrane signaling receptor activity
•
death receptor activity
•
protein binding
•
ubiquitin protein ligase binding
•
nerve growth factor binding
Cellular component
•
extracellular region
•
nucleoplasm
•
endosome
•
cytosol
•
plasma membrane
•
integral to plasma membrane
•
cell surface
Biological process
•
apoptotic process
•
anti-apoptosis
•
axon guidance
•
central nervous system development
•
induction of apoptosis by extracellular signals
•
response to wounding
•
regulation of gene expression
•
detection of temperature stimulus
•
nerve development
•
hair follicle morphogenesis
•
membrane protein intracellular domain proteolysis
•
negative regulation of fibroblast growth factor receptor signaling pathway
•
positive regulation of odontogenesis of dentin-containing tooth
•
skin development
•
negative regulation of cell cycle
•
nerve growth factor receptor signaling pathway
•
positive regulation of fibroblast proliferation
•
negative regulation of muscle organ development
•
regulation of axonogenesis
•
negative regulation of axonogenesis
•
positive regulation of axonogenesis
•
negative regulation of hair follicle development
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
4804
18053
Ensembl
ENSG00000064300
ENSMUSG00000000120
UniProt
P08138
Q8BYY1
RefSeq (mRNA)
NM_002507.3
NM_033217.3
RefSeq (protein)
NP_002498.1
NP_150086.2
Location (UCSC)
Chr 17:
47.57 – 47.59 Mb
Chr 11:
95.57 – 95.59 Mb
PubMed
search
[1]
[2]
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