酵素 | 別名 | 主な基質 | 局在(過剰発現系) | 関連疾患 |
---|---|---|---|---|
DHHC1 | ZDHHC1 | ER | ||
DHHC2 | ZDHHC2 | PSD95, SNAP25, eNOS, Nde1, CD151, ABC transporter A1 |
ER/ゴルジ体 |
癌 |
DHHC3 |
ZDHHC3 GODZ |
PSD95, SNAP25, Gαs, GABAAγ2, eNOS, |
ゴルジ体 |
|
DHHC4 |
ZDHHC4 |
BACE1 |
ゴルジ体 |
|
DHHC5 |
ZDHHC5 |
STREX |
||
DHHC6 |
ZDHHC6 |
|||
DHHC7 |
ZDHHC7 |
PSD95, SNAP25, Gαs, GAP43, GABAAγ2, eNOS |
ゴルジ体 |
|
DHHC8 |
ZDHHC8 |
PSD95, SNAP25, eNOS, paralemmin-1 |
ゴルジ体 |
統合失調症 |
DHHC9 |
ZDHHC9 |
H-RAS, N-Ras |
ER/ゴルジ体 |
癌、X連鎖神経遅滞 |
DHHC10 |
ZDHHC11 |
ER |
||
DHHC11 |
ZDHHC23 NIDD |
ER |
癌 | |
DHHC12 |
ZDHHC12 |
ABC transporter A1 |
ER/ゴルジ体 |
|
DHHC13 |
ZDHHC24 |
huntingtin |
ER |
|
DHHC14 |
ZDHHC14 |
ER |
||
DHHC15 |
ZDHHC15 |
PSD95, GAP43, GABAAγ2, BACE1, CD151 |
ゴルジ体 |
X連鎖神経遅滞 |
DHHC16 |
ZDHHC16 |
ER |
||
DHHC17 |
ZDHHC17 HIP14 |
SNAP25, huntingtin, |
ゴルジ体 |
ハンチントン病、癌 |
DHHC18 |
ZDHHC18 |
ゴルジ体 |
||
DHHC19 |
ZDHHC19 |
R-Ras |
ER |
|
DHHC20 |
ZDHHC20 |
BACE1, ABC transporter 1 |
細胞膜 |
|
DHHC21 |
ZDHHC21 |
eNOS, Lck, Fyn, ABC transporter 1 |
細胞膜 |
|
DHHC22 |
ZDHHC13 |
ER/ゴルジ体 |
||
DHHC23 |
ZDHHC25 |
|||
ZDHHC22 |