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PBB/93986
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2014年6月3日 (火) 23:22時点における
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Forkhead box P2
ファイル:2a07.pdb
PDB
rendering based on 2a07.
Available structures
PDB
2A07
,
2AS5
Identifiers
Symbols
FOXP2
; CAGH44; SPCH1; TNRC10
External IDs
OMIM
:
605317
MGI
:
2148705
HomoloGene
:
33482
GeneCards
:
FOXP2 Gene
Gene Ontology
Molecular function
•
DNA binding
•
chromatin binding
•
double-stranded DNA binding
•
sequence-specific DNA binding transcription factor activity
•
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
•
transcription factor binding
•
DNA binding, bending
•
protein homodimerization activity
•
sequence-specific DNA binding
•
metal ion binding
•
protein heterodimerization activity
Cellular component
•
transcription factor complex
•
cytoplasm
Biological process
•
positive regulation of mesenchymal cell proliferation
•
pattern specification process
•
skeletal muscle tissue development
•
embryo development
•
post-embryonic development
•
cerebellum development
•
caudate nucleus development
•
putamen development
•
cerebral cortex development
•
growth
•
vocal learning
•
camera-type eye development
•
negative regulation of transcription, DNA-dependent
•
lung alveolus development
•
smooth muscle tissue development
•
regulation of sequence-specific DNA binding transcription factor activity
•
righting reflex
•
positive regulation of epithelial cell proliferation involved in lung morphogenesis
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
93986
114142
Ensembl
ENSG00000128573
ENSMUSG00000029563
UniProt
O15409
P58463
RefSeq (mRNA)
NM_001172766
NM_053242
RefSeq (protein)
NP_001166237
NP_444472
Location (UCSC)
Chr 7:
113.73 – 114.33 Mb
Chr 6:
14.9 – 15.44 Mb
PubMed
search
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[2]
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