テンプレート:PBB/135

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Adenosine A2a receptor

ファイル:A2A receptor bilayer.png

Available structures
PDB	1MMH, 1UPE, 2YDO, 2YDV, 3EML, 3PWH, 3QAK, 3REY, 3RFM, 3UZA, 3UZC, 3VG9, 3VGA, 4EIY, 4UG2, 4UHR

Identifiers

ADORA2A; A2aR; ADORA2; RDC8

External IDs

OMIM: 102776 MGI: 99402 HomoloGene: 20166 IUPHAR: A_2A GeneCards: ADORA2A Gene

Gene Ontology
Molecular function	• G-protein coupled adenosine receptor activity • protein binding • enzyme binding • identical protein binding
Cellular component	• plasma membrane • integral component of plasma membrane • membrane
Biological process	• adenosine receptor signaling pathway • cAMP biosynthetic process • phagocytosis • apoptotic process • inflammatory response • cellular defense response • transmembrane receptor protein tyrosine kinase signaling pathway • adenylate cyclase-modulating G-protein coupled receptor signaling pathway • activation of adenylate cyclase activity • cell-cell signaling • central nervous system development • blood coagulation • sensory perception • blood circulation • positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway • neurotrophin TRK receptor signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern

ファイル:PBB GE ADORA2A 205013 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000128271

ENSMUSG00000020178

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 22:
24.42 – 24.44 Mb

Chr 10:
75.32 – 75.33 Mb

PubMed search

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