テンプレート:PBB/135

Adenosine A2a receptor
ファイル:ファイル:3EML.pdb アデノシンA2A受容体の結晶構造。3EML​による。
Available structures PDB 1MMH​, 1UPE​, 2YDO​, 2YDV​, 3EML​, 3PWH​, 3QAK​, 3REY​, 3RFM​, 3UZA​, 3UZC​, 3VG9​, 3VGA​, 4EIY​, 4UG2​, 4UHR​
Identifiers
Symbols	ADORA2A; A2aR; ADORA2; RDC8
External IDs	OMIM: 102776 MGI: 99402 HomoloGene: 20166 IUPHAR: A2A GeneCards: ADORA2A Gene
Gene Ontology Molecular function • G-protein coupled adenosine receptor activity • protein binding • enzyme binding • identical protein binding Cellular component • plasma membrane • integral component of plasma membrane • membrane Biological process • adenosine receptor signaling pathway • cAMP biosynthetic process • phagocytosis • apoptotic process • inflammatory response • cellular defense response • transmembrane receptor protein tyrosine kinase signaling pathway • adenylate cyclase-modulating G-protein coupled receptor signaling pathway • activation of adenylate cyclase activity • cell-cell signaling • central nervous system development • blood coagulation • sensory perception • blood circulation • positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway • neurotrophin TRK receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
ファイル:PBB GE ADORA2A 205013 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	135	11540
Ensembl	ENSG00000128271	ENSMUSG00000020178
UniProt	P29274	Q60613
RefSeq (mRNA)	NM_000675	NM_009630
RefSeq (protein)	NP_000666	NP_033760
Location (UCSC)	Chr 22: 24.42 – 24.44 Mb	Chr 10: 75.32 – 75.33 Mb
PubMed search	[1]	[2]