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テンプレート
:
PBB/6571
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テンプレート:PBB
2012年4月28日 (土) 10:01時点における
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Solute carrier family 18 (vesicular monoamine), member 2
Identifiers
Symbols
SLC18A2
; SVAT; SVMT; VAT2; VMAT2
External IDs
OMIM
:
193001
MGI
:
106677
HomoloGene
:
2298
GeneCards
:
SLC18A2 Gene
Gene Ontology
Molecular function
•
drug binding
•
monoamine transmembrane transporter activity
•
serotonin transmembrane transporter activity
•
enzyme binding
•
heat shock protein binding
Cellular component
•
membrane fraction
•
cytoplasm
•
plasma membrane
•
integral to plasma membrane
•
cytoplasmic vesicle membrane
•
synaptic vesicle membrane
•
dense core granule
•
cytoplasmic vesicle
•
neuron projection
•
neuronal cell body
•
terminal button
•
clathrin sculpted monoamine transport vesicle membrane
Biological process
•
response to amphetamine
•
synaptic transmission
•
neurotransmitter secretion
•
aging
•
locomotory behavior
•
response to herbicide
•
post-embryonic development
•
response to zinc ion
•
synaptic vesicle amine transport
•
monoamine transport
•
death
•
insulin secretion
•
endocytic recycling
•
cellular response to drug
•
response to cocaine
•
glucose homeostasis
•
response to starvation
•
response to corticosterone stimulus
•
negative regulation of neurotransmitter transport
•
transmembrane transport
•
cellular response to ammonium ion
Sources:
Amigo
/
QuickGO
Orthologs
Species
Human
Mouse
Entrez
6571
214084
Ensembl
ENSG00000165646
ENSMUSG00000025094
UniProt
Q05940
Q8BRU6
RefSeq (mRNA)
NM_003054.4
NM_172523.3
RefSeq (protein)
NP_003045.2
NP_766111.1
Location (UCSC)
Chr 10:
119 – 119.04 Mb
Chr 19:
59.34 – 59.37 Mb
PubMed
search
[1]
[2]