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…]] from estrone in the [[liver]] and to a lesser extent in other [[tissue (biology)|tissue]]s via 2-[[hydroxylation]] mediated by [[cytochrome P450]] [[enzyme …ast cancer cells|journal=The Journal of Steroid Biochemistry and Molecular Biology|volume=67|issue=5–6|year=1998|pages=413–419|issn=0960-0760|doi=10.1016/

…ewis, J. Raff, M., Roberts, K., Walter, P.''' <br>Molecular Biology of the Cell, 5th ed. <br>Garland Science, Taylor & Francis Group, NY, pp 538–539, 20

…er G, Tiemann I, Geiger M, Knuppen R | title = Catecholestrogens are MCF-7 cell estrogen receptor agonists | journal = J. Steroid Biochem. Mol. Biol. | vol …472688" /> These metabolites may damage [[DNA]] and other [[cell (biology)|cell]]ular components.<ref name="pmid9472688" /> However, 2-hydroxyestradiol sho

…=Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast Cancer Cells: Evidence for …sor protein, contributing to its role in cellular responses from [[Stress (biology)|stress]] and damage.<ref name=":3" />

…る<ref name=ref2>'''Bruce Alberts et al.''' <br> ''Molecular Biology of the Cell''　3rd ed 1994, 5th ed 2008<br>Garland Publishing,Inc /NewYork　</ref> � …]）が同定され, 小胞輸送説が支配的となった。細胞生物学の教科書もそれに倣った記述がなされた（例えばMolecular Biology of the Cell 3rd editionと5th editionを比較せよ）<ref name=ref2 />。

…fica]]'') and [[kudzu]]. It can also be found in ''[[Maackia amurensis]]'' cell cultures.<ref>{{Cite journal |last1=Fedoreyev |first1=S.A. |last2=Pokushalo …Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology

…f E2S are present in [[breast]] tissue, and E2S has been implicated in the biology of [[breast cancer]] via serving as an active reservoir of estradiol.<ref… …Donnell DP, Connor C, Sauer MJ | title = Evaluation of a recombinant yeast cell estrogen screening assay | journal = Environ. Health Perspect. | volume =…

…rough the [[lipid bilayer]]s of cells, E1S is unable to permeate through [[cell membrane]]s.<ref name="pmid21693170" /><ref name="pmid28527781" /><ref name …ics and biological roles|journal=Canadian Journal of Biochemistry and Cell Biology|volume=63|issue=11|year=1985|pages=1127–1144|issn=0714-7511|doi=10.1139/o

…G-Protein-Coupled Estrogen Receptor (GPER) | series = Methods in Molecular Biology | volume = 1366 | pages = 11–7 | year = 2016 | publisher = Springer | pmi …e = 2-Methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis | journal = Molecular and Cellular Endocrinology | volume = 165…

…ERβ, 3β-androstanediol positively regulates [[oxytocin]] [[neuron]]s and [[cell signaling|signaling]] in the [[paraventricular nucleus of hypothalamus]],<r

''Molecular Biology of the Cell ''　5th ed 2008<br>

…one daidzein: exploring the relevance to human health|journal=Experimental Biology and Medicine|volume=230|issue=3|pages=155–70|doi=10.1177/1535370205230003 …last1=Prossnitz|first1=Eric R.|last2=Barton|first2=Matthias|title=Estrogen biology: New insights into GPER function and clinical opportunities|journal=Molecul

…doi = 10.1021/cr60118a004 }}</ref> The total [[endometrium|endometrial]] [[cell proliferation|proliferation]] dose per cycle of different forms of hexestro …)|Distribution]] of hexestrol [[radioactivity]] in [[blood]] and [[tissue (biology)|tissue]]s after a [[subcutaneous injection]] of a [[physiological]] dose…

…embryos in Wheat: Influence of Auxin Polar Transport | journal = The Plant Cell | volume = 9 | issue = 10 | pages = 1767–1780 | date = Oct 1997 | pmid = …{{cite journal | vauthors = Formica JV, Regelson W | title = Review of the biology of quercetin and related bioflavonoids | journal = Food and Chemical Toxico

Bray, S.J. (2016). Notch signalling in context. Nat. Rev. Mol. Cell Biol. 17, 722–735. Mašek, J., and Andersson, E.R. (2017). The developmental biology of genetic Notch disorders. Development 144, 1743–1763.

…itro effects of estetrol on receptor binding, drug targets and human liver cell metabolism |journal=Climacteric |volume=11 |issue=Suppl 1 |pages=64–68 |d …7451327" /> Conversely, the effects of estetrol in certain other [[tissue (biology)|tissue]]s such as [[breast]]/[[mammary gland]], [[liver]], [[vascular syst

…by binding to the [[estrogen receptor]] and destabilizing it, causing the cell's normal [[protein degradation]] processes to destroy it.<ref name=NRDD2016 …ptor unstable and misfold, which in turn leads normal processes inside the cell to degrade it.<ref name=NRDD2016/>

…rt>'''Scott F. Gilbert & Michael J. F. Baressi. (2016)'''<br>Developmental Biology, Eleventh Edition<br>Sinauer Associates Inc.</ref>をもとに作成。]] | ホメオボックス型 || 中脳、後脳（R1-R3） || R3領域が矮小化 || 大腸癌（Colon Small Cell Carcinoma）、[[Optiz-G/BBB Syndrome]]（オピッツ症候群：脳、顔

…AFC...58.3002A }}</ref> It can also be found in ''[[Maackia amurensis]]'' cell cultures.<ref>{{cite journal |last1=Fedoreyev |first1=S.A |last2=Pokushalov …1=Prossnitz |first1=Eric R. |last2=Barton |first2=Matthias |title=Estrogen biology: New insights into GPER function and clinical opportunities |journal=Molecu