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PBB/81
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Actinin, alpha 4
PDB
rendering based on 1wlx.
Available structures
PDB
1WLX
,
1YDI
,
2R0O
Identifiers
Symbols
ACTN4
; ACTININ-4; FSGS; FSGS1
External IDs
OMIM
:
604638
MGI
:
1890773
HomoloGene
:
55857
GeneCards
:
ACTN4 Gene
Gene Ontology
Molecular function
•
nucleoside binding
•
actin binding
•
integrin binding
•
calcium ion binding
•
protein binding
•
protein homodimerization activity
•
protein N-terminus binding
•
actin filament binding
Cellular component
•
stress fiber
•
extracellular region
•
nucleus
•
cytoplasm
•
ribonucleoprotein complex
•
cortical cytoskeleton
•
platelet alpha granule lumen
•
pseudopodium
•
protein complex
•
perinuclear region of cytoplasm
Biological process
•
response to hypoxia
•
platelet degranulation
•
blood coagulation
•
protein transport
•
platelet activation
•
positive regulation of sodium:hydrogen antiporter activity
•
regulation of apoptotic process
•
positive regulation of pinocytosis
•
actin filament bundle assembly
•
negative regulation of cellular component movement
•
positive regulation of cellular component movement
•
positive regulation of cellular component movement
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
81
60595
Ensembl
ENSG00000130402
ENSMUSG00000054808
UniProt
O43707
P57780
RefSeq (mRNA)
NM_004924.4
NM_021895.2
RefSeq (protein)
NP_004915.2
NP_068695.1
Location (UCSC)
Chr 19:
39.14 – 39.22 Mb
Chr 7:
29.68 – 29.75 Mb
PubMed
search
[1]
[2]
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