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|+ | |+ 表1 主なS-パルミトイル化タンパク質<br> | ||
表1 主なS-パルミトイル化タンパク質<br> | |||
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| ファミリー<br> | | ファミリー<br> | ||
| 主な例<br> | | 主な例<br> | ||
|- | |- | ||
| '''Signalling protein'''<br> Small GTPase<br> Gα subunit<br> Src family<br> Others<br> | | '''Signalling protein'''<br> Small GTPase<br> Gα subunit<br> Src family<br> Others<br> | ||
| <br>H-Ras, N-Ras,R-Ras, RhoB, Cdc42 isoform 2, Rab10<br>Gαs, Gαq, Gαi2<br>Yes, Fyn, Lyn, Lck, Hcr, Fgr, Yrk<br>GAP43, eNOS, Paraleminin, Huntingtin, GAD65, Stathmin2<br> | | <br>H-Ras, N-Ras,R-Ras, RhoB, Cdc42 isoform 2, Rab10<br>Gαs, Gαq, Gαi2<br>Yes, Fyn, Lyn, Lck, Hcr, Fgr, Yrk<br>GAP43, eNOS, Paraleminin, Huntingtin, GAD65, Stathmin2<br> | ||
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'''Transmembrane'''<br> Ion channel<br> GPCR<br> Cell adhesion molecule<br> Transporter<br> Matrix metalloproteinase<br> Myelin associated<br> Secretase<br> Cell death signalling<br> | '''Transmembrane'''<br> Ion channel<br> GPCR<br> Cell adhesion molecule<br> Transporter<br> Matrix metalloproteinase<br> Myelin associated<br> Secretase<br> Cell death signalling<br> | ||
| GluR1/2, GABAA γ2, Aquaporin 4, Kv1.1<br>Rhodopsin, β2-adrenergic receptor, <br>Integrin α6, CD4, CD8, CD9, NCAM140, Neurofascin, DCC<br>EAAT1, EAAT3<br>MT1-MMP<br>PLP, GPM6A<br>β-secretase, Nicastrin<br>Fas, NGFR | | GluR1/2, GABAA γ2, Aquaporin 4, Kv1.1<br>Rhodopsin, β2-adrenergic receptor, <br>Integrin α6, CD4, CD8, CD9, NCAM140, Neurofascin, DCC<br>EAAT1, EAAT3<br>MT1-MMP<br>PLP, GPM6A<br>β-secretase, Nicastrin<br>Fas, NGFR | ||
|- | |- | ||
| '''Adaptor, Scaffold'''<br> | | '''Adaptor, Scaffold'''<br> | ||
| PSD95, PSD93α/β, GRIP1/2, Delphilin<br> | | PSD95, PSD93α/β, GRIP1/2, Delphilin<br> | ||
|- | |- | ||
| '''Viral protein'''<br> | | '''Viral protein'''<br> | ||
| Influenza HA H1 subunit, Sindbis virus E2 protein, HIV-1 gp160<br> | | Influenza HA H1 subunit, Sindbis virus E2 protein, HIV-1 gp160<br> | ||
|- | |- | ||
| '''N-palmitoylated protein'''<br> | | '''N-palmitoylated protein'''<br> | ||
| Sonic Hedgehog, Wnt, Ghrelin <br> | | Sonic Hedgehog, Wnt, Ghrelin <br> | ||
|} | |} | ||
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表２ パルミチルトランスフェラーゼ | |||
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