テンプレート:PBB/6261

Ryanodine receptor 1 (skeletal)
PDB rendering based on 2bcx.
Available structures PDB 2bcx​
Identifiers
Symbols	RYR1; CCO; MHS; MHS1; RYDR; RYR; RYR-1; SKRR
External IDs	OMIM: 180901 MGI: 99659 HomoloGene: 68069 IUPHAR: RyR1 GeneCards: RYR1 Gene
Gene Ontology Molecular function • protease binding • ryanodine-sensitive calcium-release channel activity • ryanodine-sensitive calcium-release channel activity • voltage-gated calcium channel activity • calcium channel activity • calcium ion binding • calmodulin binding • calcium-release channel activity Cellular component • membrane fraction • cytoplasm • smooth endoplasmic reticulum • plasma membrane • integral to plasma membrane • cell cortex • junctional sarcoplasmic reticulum membrane • terminal cisterna • sarcoplasmic reticulum • junctional membrane complex • T-tubule • I band • sarcoplasmic reticulum membrane Biological process • response to hypoxia • outflow tract morphogenesis • calcium ion transport • muscle contraction • release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • response to caffeine • skin development • ossification involved in bone maturation • skeletal muscle fiber development • release of sequestered calcium ion into cytosol • cytosolic calcium ion homeostasis • regulation of calcium ion transport via voltage-gated calcium channel activity • calcium ion transmembrane transport • cellular response to caffeine Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6261	20190
Ensembl	ENSG00000196218	ENSMUSG00000030592
UniProt	P21817	E9PZQ0
RefSeq (mRNA)	NM_000540.2	NM_009109.2
RefSeq (protein)	NP_000531.2	NP_033135.2
Location (UCSC)	Chr 19: 38.92 – 39.08 Mb	Chr 7: 29 – 29.13 Mb
PubMed search	[1]	[2]