テンプレート:PBB/22871

Neuroligin 1
Identifiers
Symbols	NLGN1; NL1
External IDs	OMIM: 600568 MGI: 2179435 HomoloGene: 56690 GeneCards: NLGN1 Gene
Gene Ontology Molecular function • carboxylesterase activity • receptor activity • neurexin family protein binding • protein dimerization activity • cell adhesion molecule binding Cellular component • integral to plasma membrane • cell surface • postsynaptic density • N-methyl-D-aspartate selective glutamate receptor complex • cell junction • dendrite • filopodium tip • synapse • postsynaptic membrane Biological process • regulation of respiratory gaseous exchange by neurological system process • protein targeting • heterophilic cell-cell adhesion • neuron cell-cell adhesion • nervous system development • synapse assembly • positive regulation of intracellular protein kinase cascade • synaptic vesicle targeting • calcium-dependent cell-cell adhesion • neuronal signal transduction • positive regulation of synaptic transmission, GABAergic • establishment of protein localization • regulation of neuron differentiation • cytoskeletal matrix organization at active zone • protein homooligomerization • protein heterotetramerization • positive regulation of filopodium assembly • positive regulation of synapse assembly • positive regulation of synaptic transmission, glutamatergic • positive regulation of dendritic spine development • terminal button organization • synaptic vesicle clustering • postsynaptic membrane assembly • presynaptic membrane assembly • alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering • N-methyl-D-aspartate receptor clustering • neurexin clustering • postsynaptic density protein 95 clustering • receptor localization to synapse • positive regulation of ruffle assembly • positive regulation of synaptic vesicle endocytosis • positive regulation of synaptic vesicle exocytosis • regulation of N-methyl-D-aspartate selective glutamate receptor activity • regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity • positive regulation of excitatory postsynaptic membrane potential Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	22871	192167
Ensembl	ENSG00000169760	ENSMUSG00000063887
UniProt	Q8N2Q7	Q99K10
RefSeq (mRNA)	NM_014932	NM_001163387
RefSeq (protein)	NP_055747	NP_001156859
Location (UCSC)	Chr 3: 173.11 – 174 Mb	Chr 3: 25.43 – 26.13 Mb
PubMed search	[1]	[2]