テンプレート:PBB/9378

Neurexin 1
ニューレキシンLNSドメイン(PDB1c4r​に基づく)。
Available structures PDB 3B3Q​, 1c4r​, 3BIW​, 2R1B​
Identifiers
Symbols	NRXN1; Hs.22998; PTHSL2; SCZD17
External IDs	OMIM: 600565 HomoloGene: 21005 GeneCards: NRXN1 Gene
Gene Ontology Molecular function • receptor activity • receptor binding • calcium channel regulator activity • protein binding • acetylcholine receptor binding • metal ion binding • calcium-dependent protein binding • cell adhesion molecule binding • neuroligin family protein binding Cellular component • plasma membrane • integral to plasma membrane • cell surface • integral to membrane • cell junction • endocytic vesicle • presynaptic membrane • axonal growth cone Biological process • angiogenesis • cell adhesion • heterophilic cell-cell adhesion • neuron cell-cell adhesion • neurotransmitter secretion • axon guidance • learning • calcium-dependent cell-cell adhesion • neuronal signal transduction • adult behavior • social behavior • pigmentation • establishment of protein localization • neuromuscular process controlling balance • positive regulation of synapse assembly • positive regulation of synaptic transmission, glutamatergic • prepulse inhibition • face morphogenesis • vocalization behavior • positive regulation of establishment of protein localization to plasma membrane • positive regulation of synapse maturation • synaptic vesicle clustering • postsynaptic membrane assembly • presynaptic membrane assembly • gamma-aminobutyric acid receptor clustering • N-methyl-D-aspartate receptor clustering • gephyrin clustering • guanylate kinase-associated protein clustering • neuroligin clustering • postsynaptic density protein 95 clustering • receptor localization to synapse • regulation of N-methyl-D-aspartate selective glutamate receptor activity • regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity • positive regulation of excitatory postsynaptic membrane potential • regulation of grooming behavior Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9378	18189
Ensembl	ENSG00000179915	ENSMUSG00000024109
UniProt	P58400	Q9CS84
RefSeq (mRNA)	NM_001135659	NM_020252
RefSeq (protein)	NP_001129131	NP_064648
Location (UCSC)	Chr 2: 50.15 – 51.26 Mb	Chr 17: 90.03 – 91.09 Mb
PubMed search	[1]	[2]