β-Zearalenol
β-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the β epimer of α-zearalenol and along with α-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively high proportion of α-zearalenol is formed from zearalenone compared to β-zearalenol in humans.[3] β-Zearalenol is about the same or slightly less potent as an estrogen relative to zearalenone.[1]
| ファイル:Beta Zearalenol.svg | |
|---|---|
| Systematic (IUPAC) name | |
| (2E,7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,14,16-tetraen-13-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 71030-11-0 |
| ATC code | ? |
| PubChem | CID 6437352 |
| ChemSpider | 5908979 |
| UNII | 35E809PP7O |
| KEGG | C14751 |
| ChEBI | CHEBI:35072 |
| Synonyms | beta-Zearalenol; beta-trans-Zearalenol |
| Chemical data | |
| Formula | C18H24O5 |
| |
See also
- Taleranol (β-zearalanol)
- Zeranol (α-zearalanol)
- Zearalanone
References
- ↑ 1.0 1.1 Bottalico A, Logrieco A, Visconti A (January 1989). "Fusarium species and their mycotoxins in infected cereals in the field and in stored grains". In Chelkowski J (ed.). Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. pp. 85–119. ISBN 978-1-4832-9785-9.
- ↑ Alldrick AJ, Hajšelová M (January 2004). "Zearalenone". In Magan N, Olsen M (eds.). Mycotoxins in Food: Detection and Control. Woodhead Publishing. pp. 353–366. ISBN 978-1-85573-733-4.
- ↑ 3.0 3.1 Eriksen GS, Alexander J (1998). "Zearalenone". Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. pp. 61–. ISBN 978-92-893-0149-7.