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PBB/1742
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テンプレート:PBB
2013年11月2日 (土) 13:34時点における
WikiSysop
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による版
(ページの作成:「{{GNF_Protein_box | Name = PSD-95 | image = 1BFE.pdb | image_source = PSD-95 第3PDZドメインの立体構造。1BFEによる。 | PDB = {{PDB2|1KEF}}, {{PDB2|3I4W}...」)
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PSD-95
PSD-95 第3PDZドメインの立体構造。1BFEによる。
Available structures
PDB
1KEF
,
3I4W
,
3K82
,
3ZRT
Identifiers
Symbols
DLG4
; PSD-95; SAP-90; SAP90
External IDs
OMIM
:
602887
MGI
:
1277959
HomoloGene
:
1047
GeneCards
:
DLG4 Gene
Gene Ontology
Molecular function
•
protein binding
•
protein C-terminus binding
•
protein phosphatase binding
•
PDZ domain binding
•
beta-1 adrenergic receptor binding
•
P2Y1 nucleotide receptor binding
•
protein complex binding
•
ionotropic glutamate receptor binding
•
ATP-activated nucleotide receptor activity
•
ADP-activated nucleotide receptor activity
•
scaffold protein binding
Cellular component
•
plasma membrane
•
synaptic vesicle
•
ionotropic glutamate receptor complex
•
postsynaptic density
•
cell junction
•
endocytic vesicle membrane
•
cortical cytoskeleton
•
extrinsic to internal side of plasma membrane
•
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
•
dendrite cytoplasm
•
juxtaparanode region of axon
•
neuron projection terminus
•
neuron spine
•
synapse
•
postsynaptic membrane
•
excitatory synapse
Biological process
•
adenosine receptor signaling pathway
•
negative regulation of receptor internalization
•
protein complex assembly
•
signal transduction
•
synaptic transmission
•
nervous system development
•
axon guidance
•
learning
•
synaptic vesicle maturation
•
social behavior
•
protein localization to synapse
•
locomotory exploration behavior
•
establishment of protein localization
•
positive regulation of transcription from RNA polymerase II promoter
•
regulation of long-term neuronal synaptic plasticity
•
positive regulation of synaptic transmission
•
neuromuscular process controlling balance
•
dendritic spine morphogenesis
•
vocalization behavior
•
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering
•
receptor localization to synapse
•
regulation of N-methyl-D-aspartate selective glutamate receptor activity
•
positive regulation of excitatory postsynaptic membrane potential
•
regulation of grooming behavior
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
1742
13385
Ensembl
ENSG00000132535
ENSMUSG00000020886
UniProt
P78352
Q62108
RefSeq (mRNA)
NM_001128827
NM_001109752
RefSeq (protein)
NP_001122299
NP_001103222
Location (UCSC)
Chr 17:
7.09 – 7.12 Mb
Chr 11:
70.02 – 70.05 Mb
PubMed
search
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