テンプレート:PBB/3060

Orexin neuropeptide
	Solution phase NMR structure of orexin A based on the PDB coordinates 1R02.
Available structures
PDB	1CQ0, 1R02, 1UVQ, 1WSO
Identifiers
Symbols	HCRT; NRCLP1; OX; PPOX
External IDs	OMIM: 602358 HomoloGene: 1166 GeneCards: HCRT Gene
Gene Ontology
Molecular function	• neuropeptide hormone activity; • type 1 hypocretin receptor binding; • type 2 hypocretin receptor binding;
Cellular component	• extracellular region; • rough endoplasmic reticulum; • synaptic vesicle; • cell junction; • secretory granule; • perinuclear region of cytoplasm;
Biological process	• phospholipase C-activating G-protein coupled receptor signaling pathway; • elevation of cytosolic calcium ion concentration; • protein kinase C-activating G-protein coupled receptor signaling pathway; • neuropeptide signaling pathway; • synaptic transmission; • negative regulation of DNA replication; • eating behavior; • negative regulation of potassium ion transport; • regulation of neurotransmitter secretion; • positive regulation of calcium ion transport; • negative regulation of transmission of nerve impulse; • positive regulation of transmission of nerve impulse; • regulation of excitatory postsynaptic membrane potential;
	Sources: Amigo / QuickGO
Orthologs
	v; t; e;

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