Reelin (Q14331165)

Sialidase superfamily

1 reference

Galactose-binding-like domain superfamily

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

Reeler domain, protein family

1 reference

inferred from protein domain or family

EGF-like domain, protein family

1 reference

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

very-low-density lipoprotein particle receptor binding

1 reference

9 May 2019

Reelin is a ligand for lipoprotein receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

serine-type peptidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

3 references

9 May 2019

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Structural basis for specific recognition of reelin by its receptors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

extracellular matrix structural constituent

IPI

1 reference

1 January 2018

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60841&geneProductId=UniProtKB:Q60841

extracellular matrix structural constituent

HDA

extracellular matrix structural constituent

RCA

1 reference

9 May 2019

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

lipoprotein particle receptor binding

RCA

3 references

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Lack of Reelin causes malpositioning of nigral dopaminergic neurons: Evidence from comparison of normal and Relnrl mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Reelin activates SRC family tyrosine kinases in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Developmental roles of p73 in Cajal-Retzius cells and cortical patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

collagen-containing extracellular matrix

ISO

1 reference

9 May 2019

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin activates SRC family tyrosine kinases in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Lack of Reelin causes malpositioning of nigral dopaminergic neurons: Evidence from comparison of normal and Relnrl mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

receptor localization to synapse

IBA

biological process

Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation

regulation of behavior

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of small GTPase mediated signal transduction

1 reference

9 May 2019

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

cerebral cortex tangential migration

1 reference

9 May 2019

A novel mode of tangential migration of cortical projection neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of long-term synaptic potentiation

1 reference

9 May 2019

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

NMDA glutamate receptor clustering

Absence of Reelin results in altered nociception and aberrant neuronal positioning in the dorsal spinal cord

spinal cord patterning

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of protein tyrosine kinase activity

postsynaptic density assembly

1 reference

9 May 2019

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

modulation of chemical synaptic transmission

IC

1 reference

9 May 2019

Functional consequences of hippocampal neuronal ectopia in the apolipoprotein E receptor-2 knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

postsynaptic density protein 95 clustering

glial cell differentiation

1 reference

9 May 2019

Reelin signaling directly affects radial glia morphology and biochemical maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

regulation of NMDA receptor activity

1 reference

9 May 2019

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

lateral motor column neuron migration

1 reference

9 May 2019

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

ventral spinal cord development

1 reference

9 May 2019

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of CREB transcription factor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of synaptic transmission, glutamatergic

4 references

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

layer formation in cerebral cortex

1 reference

9 May 2019

Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

Absence of Reelin results in altered nociception and aberrant neuronal positioning in the dorsal spinal cord

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of lateral motor column neuron migration

1 reference

9 May 2019

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

cerebral cortex development

1 reference

9 May 2019

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

regulation of gene expression

1 reference

9 May 2019

Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of excitatory postsynaptic potential

4 references

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of phosphatidylinositol 3-kinase signaling

peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

Reelin activates SRC family tyrosine kinases in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex

forebrain development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

cell morphogenesis involved in differentiation

1 reference

9 May 2019

Reelin signaling directly affects radial glia morphology and biochemical maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

hippocampus development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

positive regulation of dendritic spine morphogenesis

4 references

9 May 2019

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

protein localization to synapse

positive regulation of TOR signaling

1 reference

9 May 2019

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

long-term potentiation

1 reference

9 May 2019

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Lack of Reelin causes malpositioning of nigral dopaminergic neurons: Evidence from comparison of normal and Relnrl mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Dissection of the cellular and molecular events that position cerebellar Purkinje cells: a study of the math1 null-mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Postnatal shifts of interneuron position in the neocortex of normal and reeler mice: evidence for inward radial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

dentate gyrus development

ISO

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Dissection of the cellular and molecular events that position cerebellar Purkinje cells: a study of the math1 null-mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Postnatal shifts of interneuron position in the neocortex of normal and reeler mice: evidence for inward radial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Lack of Reelin causes malpositioning of nigral dopaminergic neurons: Evidence from comparison of normal and Relnrl mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

central nervous system development

IBA

3 references

9 May 2019

Evidence for a cell-specific action of Reelin in the spinal cord

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60841

1 reference

EGF-like, conserved site

1 reference

EGF-like domain

1 reference