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P2Y受容体 - 版の履歴
2024-03-28T23:00:24Z
このウィキのこのページに関する変更履歴
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https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32599&oldid=prev
2015年12月7日 (月) 13:52にWikiSysopによる
2015-12-07T13:52:55Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年12月7日 (月) 22:52時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2">2行目:</td>
<td colspan="2" class="diff-lineno">2行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font size="+1">[http://yakkou.phar.kyushu-u.ac.jp/Member.html 津田 誠]</font><br></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><font size="+1">[http://yakkou.phar.kyushu-u.ac.jp/Member.html 津田 誠]</font><br></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>''九州大学大学院薬学研究院 医療薬科学部門 薬理学分野''<br></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>''九州大学大学院薬学研究院 医療薬科学部門 薬理学分野''<br></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>DOI:<selfdoi /><del style="font-weight: bold; text-decoration: none;"> 原稿受付日:2013年6月14日 原稿完成日:2015年XX月XX日</del><br></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>DOI:<selfdoi /><ins style="font-weight: bold; text-decoration: none;"> 原稿受付日:2013年6月14日 原稿完成日:2015年12月7日</ins><br></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>担当編集委員:[http://researchmap.jp/2rikenbsi 林 康紀](独立行政法人理化学研究所 脳科学総合研究センター)<br></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>担当編集委員:[http://researchmap.jp/2rikenbsi 林 康紀](独立行政法人理化学研究所 脳科学総合研究センター)<br></div></td></tr>
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WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32598&oldid=prev
2015年12月7日 (月) 13:52にWikiSysopによる
2015-12-07T13:52:35Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年12月7日 (月) 22:52時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l21">21行目:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表1. プリン受容体の分類</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表1. プリン受容体の分類</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称''' ||'''<del style="font-weight: bold; text-decoration: none;">サブタイプ</del>'''|| '''リガンド''' || '''作用機構'''</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称''' ||'''<ins style="font-weight: bold; text-decoration: none;">下位分類</ins>'''|| '''リガンド''' || '''作用機構'''</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|<del style="font-weight: bold; text-decoration: none;">'''</del>[[P1受容体]]<del style="font-weight: bold; text-decoration: none;">''' </del>||A<sub>1</sub>、A<sub>2A</sub>、A<sub>2B</sub>,A<sub>3</sub>受容体|| [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|[[P1受容体]] ||A<sub>1</sub>、A<sub>2A</sub>、A<sub>2B</sub>,A<sub>3</sub>受容体|| [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|'''P2受容体'''||'''[[P2X受容体]]''' ||<del style="font-weight: bold; text-decoration: none;">P2X<sub>1−7</sub>受容体</del>||ATP || [[リガンド依存性イオンチャンネル]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|'''P2受容体'''||'''[[P2X受容体]]''' ||<ins style="font-weight: bold; text-decoration: none;">P2X1−7受容体</ins>||ATP || [[リガンド依存性イオンチャンネル]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|| '''[[P2Y受容体]]''' ||P2Y<sub><del style="font-weight: bold; text-decoration: none;">1−14</del></sub>受容体||[[ヌクレオチド]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|| '''[[P2Y受容体]]''' ||P2Y<sub><ins style="font-weight: bold; text-decoration: none;">1, 2, 4, 6, 11−14</ins></sub>受容体||[[ヌクレオチド]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[wj:アデノシン三リン酸|ATP]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[wj:アデノシン三リン酸|ATP]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[wj:アデノシン二リン酸|ADP]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[wj:アデノシン二リン酸|ADP]]</div></td></tr>
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<td colspan="2" class="diff-lineno">54行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>12</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>12</sub>受容体===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> Giタンパク質と共役しアデニル酸シクラーゼを抑制する。[[Gβγタンパク質|G<sub>βγ</sub>]]の作用で[[PI3キナーゼ|PI<sub>3</sub>キナーゼ]]を活性化するという報告もある。ADPを内因性リガンドとし、ATPやその類似化合物は拮抗薬として作用すると報告されている。主に[[巨核球]]・血小板でその発現が見られGαi<sub>2</sub>を介したシグナルによってP2Y<sub>1</sub>受容体とともに血小板凝集作用を示す<ref name=ref91 />。中枢神経系ではミクログリアで高発現し、[[細胞移動|細胞の移動]]・突起伸展に関わっている<ref name=ref92><pubmed>11245682</pubmed></ref> <ref name=ref93><pubmed>17115040</pubmed></ref>。阻害薬の抗血小板作用が注目され、[[プロドラッグ]]で非可逆的なP2Y<sub>12</sub>受容体阻害薬である[[クロピドグレル]](プラビックス®、[[wj:サノフィ・アベンティス|サノフィ・アベンティス]])、[[プラスグレル]](エフィエント®、[[wj:第一三共]])が医薬品として認可を受けおり、[[可逆的阻害薬]]の[[チカグレロル]](ブリリンタ、[[wj:アストラゼネカ|アストラゼネカ]])も開発中である。</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> Giタンパク質と共役しアデニル酸シクラーゼを抑制する。[[Gβγタンパク質|G<sub>βγ</sub>]]の作用で[[PI3キナーゼ|PI<sub>3</sub>キナーゼ]]を活性化するという報告もある。ADPを内因性リガンドとし、ATPやその類似化合物は拮抗薬として作用すると報告されている。主に[[巨核球]]・血小板でその発現が見られGαi<sub>2</sub>を介したシグナルによってP2Y<sub>1</sub>受容体とともに血小板凝集作用を示す<ref name=ref91 />。中枢神経系ではミクログリアで高発現し、[[細胞移動|細胞の移動]]・突起伸展に関わっている<ref name=ref92><pubmed>11245682</pubmed></ref> <ref name=ref93><pubmed>17115040</pubmed></ref>。阻害薬の抗血小板作用が注目され、[[プロドラッグ]]で非可逆的なP2Y<sub>12</sub>受容体阻害薬である[[クロピドグレル]](プラビックス®、[[wj:サノフィ・アベンティス|サノフィ・アベンティス]])、[[プラスグレル]](エフィエント®、[[wj:<ins style="font-weight: bold; text-decoration: none;">第一三共|</ins>第一三共]])が医薬品として認可を受けおり、[[可逆的阻害薬]]の[[チカグレロル]](ブリリンタ、[[wj:アストラゼネカ|アストラゼネカ]])も開発中である。</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>13</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>13</sub>受容体===</div></td></tr>
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WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32553&oldid=prev
WikiSysop: /* P2Y14受容体 */
2015-11-28T03:28:23Z
<p><span dir="auto"><span class="autocomment">P2Y14受容体</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月28日 (土) 12:28時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l67">67行目:</td>
<td colspan="2" class="diff-lineno">67行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY1</del>|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/<sub>11</sub> || ADP>ATP||[[ADPβS]]<br>[[2MeSADP]]||[[MRS2365]]<br>[[2-Cl-ADP]] ([[α-BH3]])||[[MRS2500]]<br>[[BMS compound 16]]<br>[[MRS2279]]<br>[[MRS2179]]<br>[[2‐2'‐ピリジルイサトゲントシラート]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y1受容体</ins>|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/<sub>11</sub> || ADP>ATP||[[ADPβS]]<br>[[2MeSADP]]||[[MRS2365]]<br>[[2-Cl-ADP]] ([[α-BH3]])||[[MRS2500]]<br>[[BMS compound 16]]<br>[[MRS2279]]<br>[[MRS2179]]<br>[[2‐2'‐ピリジルイサトゲントシラート]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY2</del>|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||[[デヌホソル]]<br>[[ジクアホソルナトリウム]]||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A|Ap<sub>4</sub>A]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y2受容体</ins>|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||[[デヌホソル]]<br>[[ジクアホソルナトリウム]]||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A|Ap<sub>4</sub>A]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY4</del>|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || UTP>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y4受容体</ins>|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || UTP>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY6</del>|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub>|| UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[MRS2957]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y6受容体</ins>|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub>|| UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[MRS2957]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY11</del>|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| Gs and Gq/<sub>11</sub> || ATP>UTP||||[[AR-C67085]]<br>[[NF546]]<br>[[NAADP]]<br>[[NAD]]||[[NF340]]<br>[[NF157]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y11受容体</ins>|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| Gs and Gq/<sub>11</sub> || ATP>UTP||||[[AR-C67085]]<br>[[NF546]]<br>[[NAADP]]<br>[[NAD]]||[[NF340]]<br>[[NF157]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY12</del>|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| Gi||ADP||[[2MeSADP]]||||[[PSB-0739]]<br>[[AZD1283]]<br>[[チカグレロル]]<br>[[ARL66096]]<br>[[クロピドグレル]]<br>[[プラスグレル]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y12受容体</ins>|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| Gi||ADP||[[2MeSADP]]||||[[PSB-0739]]<br>[[AZD1283]]<br>[[チカグレロル]]<br>[[ARL66096]]<br>[[クロピドグレル]]<br>[[プラスグレル]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY13</del>|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||[[MRS2211]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y13受容体</ins>|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||[[MRS2211]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[<del style="font-weight: bold; text-decoration: none;">P2RY14</del>|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/experiment/show/100144167 100144167]|| Gi || UDP ≥ UDP-グルコース||[[MRS2690]]||||[[PPTN]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[<ins style="font-weight: bold; text-decoration: none;">P2Y14受容体</ins>|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/experiment/show/100144167 100144167]|| Gi || UDP ≥ UDP-グルコース||[[MRS2690]]||||[[PPTN]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、<ref name=ref3 />より翻訳、改変。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、<ref name=ref3 />より翻訳、改変。</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32541&oldid=prev
2015年11月28日 (土) 03:09にWikiSysopによる
2015-11-28T03:09:12Z
<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月28日 (土) 12:09時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l6">6行目:</td>
<td colspan="2" class="diff-lineno">6行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></div></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></div></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">英語名: P2 </del>purinergic <del style="font-weight: bold; text-decoration: none;">receptor、Purinoceptor 独:P2 </del>purinerge Rezeptoren 仏:récepteur purinergique <del style="font-weight: bold; text-decoration: none;">P2</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">英語名:P2Y </ins>purinergic <ins style="font-weight: bold; text-decoration: none;">receptor、Purinoceptor 独:P2Y </ins>purinerge Rezeptoren 仏:récepteur purinergique <ins style="font-weight: bold; text-decoration: none;">P2Y</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">同義語:ATP受容体</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{box|text= P2Y受容体は、ATP、UTPなどのヌクレオチドをリガンドとする細胞表面受容体である。Gタンパク質共役型受容体に属する。}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{box|text= P2Y受容体は、ATP、UTPなどのヌクレオチドをリガンドとする細胞表面受容体である。Gタンパク質共役型受容体に属する。}}</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l15">15行目:</td>
<td colspan="2" class="diff-lineno">17行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> P2Y受容体は、同じくプリンヌクレオチドをリガンドとするが[[リガンド依存性イオンチャネル型受容体]]である[[P2X受容体]]、[[アデノシン]]に対する受容体である[[P1受容体]]ファミリーと共に[[プリン受容体]]と呼ばれている<ref name=ref1><pubmed>17429044</pubmed></ref> <ref name=ref2><pubmed>18591979</pubmed></ref>('''表1、2''')。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> P2Y受容体は、同じくプリンヌクレオチドをリガンドとするが[[リガンド依存性イオンチャネル型受容体]]である[[P2X受容体]]、[[アデノシン]]に対する受容体である[[P1受容体]]ファミリーと共に[[プリン受容体]]と呼ばれている<ref name=ref1><pubmed>17429044</pubmed></ref> <ref name=ref2><pubmed>18591979</pubmed></ref>('''表1、2''')。</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> なお、本項における受容体の表記は、IUPHARでのデータベース掲載名に従った<ref>[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 国際薬理学連合 Guide to Pharmacology P2Y受容体]</ref>。</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> なお、本項における受容体の表記は、IUPHARでのデータベース掲載名に従った<ref <ins style="font-weight: bold; text-decoration: none;">name=ref3</ins>>[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 国際薬理学連合 Guide to Pharmacology P2Y受容体]</ref>。</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l40">40行目:</td>
<td colspan="2" class="diff-lineno">42行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>2</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>2</sub>受容体===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> ATPおよび[[UTP]]を内因性リガンドとするGq/G<sub>11</sub>共役型の受容体である。生体内で広範に発現が確認されており、主に免疫細胞、内皮細胞、上皮細胞、[[腎臓]]、[[骨芽細胞]]などで発現している。P2Y<sub>2</sub>受容体欠損マウスの解析から、神経細胞の[[軸索]]伸長や[[分化]]への関与<ref name=ref74><pubmed>16365320</pubmed></ref>や、気道上皮細胞におけるCl<sup>-</sup>の放出への関与が示唆されている<ref name=ref75><pubmed>10473606</pubmed></ref>。炎症時における神経保護作用に関する役割にも注目が集まっている<ref name=ref76><pubmed>22528682</pubmed></ref>。[[マクロファージ]]でのP2Y<sub>2</sub>受容体は、[[アポトーシス]]細胞が放出するATPで刺激され、貪食によるクリアランスに関与する<ref name=ref77><pubmed>19741708</pubmed></ref> <ref name=ref78><pubmed>20664064</pubmed></ref>。現在、P2Y<sub>2</sub>受容体[[作動薬]][[デヌホソル]]<del style="font-weight: bold; text-decoration: none;">(Inspire Pharmaceuticals)が</del>[[嚢胞性線維症]]の吸入治療薬として開発されており(フェーズⅢ、USA)<ref name=ref79><pubmed>18276176</pubmed></ref> <ref name=ref80><pubmed>21169471</pubmed></ref>、P2Y<sub>2</sub>受容体の[[遺伝子多型]]の一つが健常人に比べ嚢胞性線維症の患者において高頻度でみられることから、嚢胞性線維症の発症および治療への関与が考えられる<ref name=ref81><pubmed>17559347</pubmed></ref>。さらに、[[ドライアイ]]治療薬としてP2Y<sub>2</sub>受容体作動薬[[ジクアホソルナトリウム]](ジクアス®点眼液3%, <del style="font-weight: bold; text-decoration: none;">参天製薬)がある。</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> ATPおよび[[UTP]]を内因性リガンドとするGq/G<sub>11</sub>共役型の受容体である。生体内で広範に発現が確認されており、主に免疫細胞、内皮細胞、上皮細胞、[[腎臓]]、[[骨芽細胞]]などで発現している。P2Y<sub>2</sub>受容体欠損マウスの解析から、神経細胞の[[軸索]]伸長や[[分化]]への関与<ref name=ref74><pubmed>16365320</pubmed></ref>や、気道上皮細胞におけるCl<sup>-</sup>の放出への関与が示唆されている<ref name=ref75><pubmed>10473606</pubmed></ref>。炎症時における神経保護作用に関する役割にも注目が集まっている<ref name=ref76><pubmed>22528682</pubmed></ref>。[[マクロファージ]]でのP2Y<sub>2</sub>受容体は、[[アポトーシス]]細胞が放出するATPで刺激され、貪食によるクリアランスに関与する<ref name=ref77><pubmed>19741708</pubmed></ref> <ref name=ref78><pubmed>20664064</pubmed></ref>。現在、P2Y<sub>2</sub>受容体[[作動薬]][[デヌホソル]]<ins style="font-weight: bold; text-decoration: none;">([[w:Inspire Pharmaceuticals|Inspire Pharmaceuticals]])が</ins>[[嚢胞性線維症]]の吸入治療薬として開発されており(フェーズⅢ、USA)<ref name=ref79><pubmed>18276176</pubmed></ref> <ref name=ref80><pubmed>21169471</pubmed></ref>、P2Y<sub>2</sub>受容体の[[遺伝子多型]]の一つが健常人に比べ嚢胞性線維症の患者において高頻度でみられることから、嚢胞性線維症の発症および治療への関与が考えられる<ref name=ref81><pubmed>17559347</pubmed></ref>。さらに、[[ドライアイ]]治療薬としてP2Y<sub>2</sub>受容体作動薬[[ジクアホソルナトリウム]](ジクアス®点眼液3%, <ins style="font-weight: bold; text-decoration: none;">[[wj:参天製薬|参天製薬]])がある。</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>4</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>4</sub>受容体===</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l81">81行目:</td>
<td colspan="2" class="diff-lineno">83行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/experiment/show/100144167 100144167]|| Gi || UDP ≥ UDP-グルコース||[[MRS2690]]||||[[PPTN]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/experiment/show/100144167 100144167]|| Gi || UDP ≥ UDP-グルコース||[[MRS2690]]||||[[PPTN]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、<del style="font-weight: bold; text-decoration: none;">[http:</del>/<del style="font-weight: bold; text-decoration: none;">/www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId</del>=<del style="font-weight: bold; text-decoration: none;">52 Guide to Pharmacology P2Y受容体のページ</del>]<del style="font-weight: bold; text-decoration: none;">より</del>[[<del style="font-weight: bold; text-decoration: none;">翻訳</del>]]<del style="font-weight: bold; text-decoration: none;">、改変。</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、<ins style="font-weight: bold; text-decoration: none;"><ref name=ref3 </ins>/<ins style="font-weight: bold; text-decoration: none;">>より翻訳、改変。</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">==関連項目=</ins>=</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">*[[プリン受容体]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">*[[P1受容体]</ins>]</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">*</ins>[[<ins style="font-weight: bold; text-decoration: none;">P2X受容体</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== 参考文献 ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== 参考文献 ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td></tr>
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WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32540&oldid=prev
WikiSysop: /* サブタイプ */
2015-11-28T03:00:08Z
<p><span dir="auto"><span class="autocomment">サブタイプ</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月28日 (土) 12:00時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l52">52行目:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>12</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>12</sub>受容体===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> Giタンパク質と共役しアデニル酸シクラーゼを抑制する。[[Gβγタンパク質|G<sub>βγ</sub>]]の作用で[[PI3キナーゼ|PI<sub>3</sub>キナーゼ]]を活性化するという報告もある。ADPを内因性リガンドとし、ATPやその類似化合物は拮抗薬として作用すると報告されている。主に[[巨核球]]・血小板でその発現が見られGαi<sub>2</sub>を介したシグナルによってP2Y<sub>1</sub>受容体とともに血小板凝集作用を示す<ref name=ref91 />。中枢神経系ではミクログリアで高発現し、[[細胞移動|細胞の移動]]・突起伸展に関わっている<ref name=ref92><pubmed>11245682</pubmed></ref> <ref name=ref93><pubmed>17115040</pubmed></ref>。阻害薬の抗血小板作用が注目され、[[プロドラッグ]]で非可逆的なP2Y<sub>12</sub>受容体阻害薬である[[クロピドグレル]](プラビックス®、[[<del style="font-weight: bold; text-decoration: none;">w</del>:サノフィ・アベンティス|サノフィ・アベンティス]])、[[プラスグレル]](エフィエント®、[[<del style="font-weight: bold; text-decoration: none;">w</del>:<del style="font-weight: bold; text-decoration: none;">第一三共製薬|</del>第一三共]])が医薬品として認可を受けおり、[[可逆的阻害薬]]の[[チカグレロル]](ブリリンタ、[[<del style="font-weight: bold; text-decoration: none;">w</del>:アストラゼネカ|アストラゼネカ]])も開発中である。</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> Giタンパク質と共役しアデニル酸シクラーゼを抑制する。[[Gβγタンパク質|G<sub>βγ</sub>]]の作用で[[PI3キナーゼ|PI<sub>3</sub>キナーゼ]]を活性化するという報告もある。ADPを内因性リガンドとし、ATPやその類似化合物は拮抗薬として作用すると報告されている。主に[[巨核球]]・血小板でその発現が見られGαi<sub>2</sub>を介したシグナルによってP2Y<sub>1</sub>受容体とともに血小板凝集作用を示す<ref name=ref91 />。中枢神経系ではミクログリアで高発現し、[[細胞移動|細胞の移動]]・突起伸展に関わっている<ref name=ref92><pubmed>11245682</pubmed></ref> <ref name=ref93><pubmed>17115040</pubmed></ref>。阻害薬の抗血小板作用が注目され、[[プロドラッグ]]で非可逆的なP2Y<sub>12</sub>受容体阻害薬である[[クロピドグレル]](プラビックス®、[[<ins style="font-weight: bold; text-decoration: none;">wj</ins>:サノフィ・アベンティス|サノフィ・アベンティス]])、[[プラスグレル]](エフィエント®、[[<ins style="font-weight: bold; text-decoration: none;">wj</ins>:第一三共]])が医薬品として認可を受けおり、[[可逆的阻害薬]]の[[チカグレロル]](ブリリンタ、[[<ins style="font-weight: bold; text-decoration: none;">wj</ins>:アストラゼネカ|アストラゼネカ]])も開発中である。</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>13</sub>受容体===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===P2Y<sub>13</sub>受容体===</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l63">63行目:</td>
<td colspan="2" class="diff-lineno">63行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表2. P2Y受容体</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表2. P2Y受容体</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト<del style="font-weight: bold; text-decoration: none;">!!</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY1|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/<sub>11</sub> || ADP>ATP||[[ADPβS]]<br>[[2MeSADP]]||[[MRS2365]]<br>[[2-Cl-ADP]] ([[α-BH3]])||[[MRS2500]]<br>[[BMS compound 16]]<br>[[MRS2279]]<br>[[MRS2179]]<br>[[2‐2'‐ピリジルイサトゲントシラート]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY1|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/<sub>11</sub> || ADP>ATP||[[ADPβS]]<br>[[2MeSADP]]||[[MRS2365]]<br>[[2-Cl-ADP]] ([[α-BH3]])||[[MRS2500]]<br>[[BMS compound 16]]<br>[[MRS2279]]<br>[[MRS2179]]<br>[[2‐2'‐ピリジルイサトゲントシラート]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||<ins style="font-weight: bold; text-decoration: none;">[[デヌホソル]]<br>[[ジクアホソルナトリウム]]</ins>||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A<ins style="font-weight: bold; text-decoration: none;">|Ap<sub>4</sub>A</ins>]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || UTP>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || UTP>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub> <del style="font-weight: bold; text-decoration: none;"> </del>|| UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[<del style="font-weight: bold; text-decoration: none;">MRS295</del>]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub>|| UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[<ins style="font-weight: bold; text-decoration: none;">MRS2957</ins>]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY11|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| Gs and Gq/<sub>11</sub> || ATP>UTP||[[AR-C67085]]<br>[[NF546]]<br>[[NAADP]]<br>[[NAD]]||[[NF340]]<del style="font-weight: bold; text-decoration: none;">||</del>[[NF157]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY11|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| Gs and Gq/<sub>11</sub> || ATP>UTP<ins style="font-weight: bold; text-decoration: none;">||</ins>||[[AR-C67085]]<br>[[NF546]]<br>[[NAADP]]<br>[[NAD]]||[[NF340]]<ins style="font-weight: bold; text-decoration: none;"><br></ins>[[NF157]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY12|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| Gi <del style="font-weight: bold; text-decoration: none;"> </del>|| ADP||[[2MeSADP]]||||[[PSB-0739]]<br>[[AZD1283]]<br>[[チカグレロル]]<br>[[ARL66096]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY12|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| Gi||ADP||[[2MeSADP]]||||[[PSB-0739]]<br>[[AZD1283]]<br>[[チカグレロル]]<br>[[ARL66096<ins style="font-weight: bold; text-decoration: none;">]]<br>[[クロピドグレル]]<br>[[プラスグレル</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||MRS2211</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2211<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/<del style="font-weight: bold; text-decoration: none;">gene</del>/show/<del style="font-weight: bold; text-decoration: none;">80135 80135</del>]|| Gi || UDP ≥ UDP-グルコース||MRS2690||||PPTN</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/<ins style="font-weight: bold; text-decoration: none;">experiment</ins>/show/<ins style="font-weight: bold; text-decoration: none;">100144167 100144167</ins>]|| Gi || UDP ≥ UDP-グルコース||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2690<ins style="font-weight: bold; text-decoration: none;">]]</ins>||||<ins style="font-weight: bold; text-decoration: none;">[[</ins>PPTN<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32539&oldid=prev
2015年11月28日 (土) 02:33にWikiSysopによる
2015-11-28T02:33:15Z
<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月28日 (土) 11:33時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l21">21行目:</td>
<td colspan="2" class="diff-lineno">21行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称''' ||'''サブタイプ'''|| '''リガンド''' || '''作用機構'''</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称''' ||'''サブタイプ'''|| '''リガンド''' || '''作用機構'''</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|'''[[P1受容体]]''' ||A<sub>1</sub>、A<sub>2A</sub><del style="font-weight: bold; text-decoration: none;">、A2</del><sub><del style="font-weight: bold; text-decoration: none;">B</del></sub>,A<sub>3</sub>受容体|| [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|'''[[P1受容体]]''' ||A<sub>1</sub>、A<sub>2A</sub><ins style="font-weight: bold; text-decoration: none;">、A</ins><sub><ins style="font-weight: bold; text-decoration: none;">2B</ins></sub>,A<sub>3</sub>受容体|| [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|'''P2受容体'''||'''[[P2X受容体]]''' ||P2X<sub>1−7</sub>受容体||ATP || [[リガンド依存性イオンチャンネル]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|'''P2受容体'''||'''[[P2X受容体]]''' ||P2X<sub>1−7</sub>受容体||ATP || [[リガンド依存性イオンチャンネル]]</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32538&oldid=prev
WikiSysop: /* P2Y受容体とは */
2015-11-28T02:32:52Z
<p><span dir="auto"><span class="autocomment">P2Y受容体とは</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月28日 (土) 11:32時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l15">15行目:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> P2Y受容体は、同じくプリンヌクレオチドをリガンドとするが[[リガンド依存性イオンチャネル型受容体]]である[[P2X受容体]]、[[アデノシン]]に対する受容体である[[P1受容体]]ファミリーと共に[[プリン受容体]]と呼ばれている<ref name=ref1><pubmed>17429044</pubmed></ref> <ref name=ref2><pubmed>18591979</pubmed></ref>('''表1、2''')。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> P2Y受容体は、同じくプリンヌクレオチドをリガンドとするが[[リガンド依存性イオンチャネル型受容体]]である[[P2X受容体]]、[[アデノシン]]に対する受容体である[[P1受容体]]ファミリーと共に[[プリン受容体]]と呼ばれている<ref name=ref1><pubmed>17429044</pubmed></ref> <ref name=ref2><pubmed>18591979</pubmed></ref>('''表1、2''')。</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"> なお、本項における受容体の表記は、IUPHAR </del>[http://www.guidetopharmacology.org 国際薬理学連合 Guide to Pharmacology]<del style="font-weight: bold; text-decoration: none;">でのデータベース掲載名に従った。</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"> なお、本項における受容体の表記は、IUPHARでのデータベース掲載名に従った<ref></ins>[http://www.guidetopharmacology.org<ins style="font-weight: bold; text-decoration: none;">/GRAC/FamilyDisplayForward?familyId=52 </ins>国際薬理学連合 Guide to Pharmacology <ins style="font-weight: bold; text-decoration: none;">P2Y受容体</ins>]<ins style="font-weight: bold; text-decoration: none;"></ref>。</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{| class="wikitable"</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表1. プリン受容体の分類</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|+表1. プリン受容体の分類</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称''' || '''リガンド''' || '''作用機構'''</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|colspan="2"|'''名称<ins style="font-weight: bold; text-decoration: none;">''' ||'''サブタイプ</ins>'''|| '''リガンド''' || '''作用機構'''</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|[[P1受容体]] || [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|<ins style="font-weight: bold; text-decoration: none;">'''</ins>[[P1受容体]]<ins style="font-weight: bold; text-decoration: none;">''' ||A<sub>1</sub>、A<sub>2A</sub>、A2<sub>B</sub>,A<sub>3</sub>受容体</ins>|| [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|P2受容体 <del style="font-weight: bold; text-decoration: none;"> </del>|| [[P2X受容体]] || <del style="font-weight: bold; text-decoration: none;">ATPなどの[[ヌクレオチド]] </del>|| [[リガンド依存性イオンチャンネル]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|<ins style="font-weight: bold; text-decoration: none;">'''</ins>P2受容体<ins style="font-weight: bold; text-decoration: none;">'''</ins>||<ins style="font-weight: bold; text-decoration: none;">'''</ins>[[P2X受容体]]<ins style="font-weight: bold; text-decoration: none;">''' </ins>||<ins style="font-weight: bold; text-decoration: none;">P2X<sub>1−7</sub>受容体||ATP </ins>|| [[リガンド依存性イオンチャンネル]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|| [[P2Y受容体]] || <del style="font-weight: bold; text-decoration: none;">ATPなどの</del>[[ヌクレオチド]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|| <ins style="font-weight: bold; text-decoration: none;">'''</ins>[[P2Y受容体]]<ins style="font-weight: bold; text-decoration: none;">''' </ins> ||<ins style="font-weight: bold; text-decoration: none;">P2Y<sub>1−14</sub>受容体||</ins>[[ヌクレオチド<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[wj:アデノシン三リン酸|ATP]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[wj:アデノシン二リン酸|ADP]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン三リン酸|UTP]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン二リン酸|UDP]]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン二リン酸グルコース|UDPグルコース</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|| [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|| [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32528&oldid=prev
2015年11月27日 (金) 00:41にWikiSysopによる
2015-11-27T00:41:15Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="ja">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月27日 (金) 09:41時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l8">8行目:</td>
<td colspan="2" class="diff-lineno">8行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>英語名: P2 purinergic receptor、Purinoceptor 独:P2 purinerge Rezeptoren 仏:récepteur purinergique P2</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>英語名: P2 purinergic receptor、Purinoceptor 独:P2 purinerge Rezeptoren 仏:récepteur purinergique P2</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>{{box|text=<del style="font-weight: bold; text-decoration: none;"> P2Y受容体は、ATPなどのプリンヌクレオチドをリガンドとする細胞表面受容体であり、Gタンパク質共役型受容体である。</del>}}</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>{{box|text=<ins style="font-weight: bold; text-decoration: none;"> P2Y受容体は、ATP、UTPなどのヌクレオチドをリガンドとする細胞表面受容体である。Gタンパク質共役型受容体に属する。</ins>}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==P2Y受容体とは==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==P2Y受容体とは==</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23">23行目:</td>
<td colspan="2" class="diff-lineno">23行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|[[P1受容体]] || [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | colspan="2"|[[P1受容体]] || [[アデノシン]] || [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|P2受容体 || [[P2X受容体]] || <del style="font-weight: bold; text-decoration: none;">ATP </del>|| [[リガンド依存性イオンチャンネル]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | rowspan="2"|P2受容体 || [[P2X受容体]] || <ins style="font-weight: bold; text-decoration: none;">ATPなどの[[ヌクレオチド]] </ins>|| [[リガンド依存性イオンチャンネル]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|| [[P2Y受容体]] || [[ヌクレオチド<del style="font-weight: bold; text-decoration: none;">]]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|| [[P2Y受容体]] || <ins style="font-weight: bold; text-decoration: none;">ATPなどの</ins>[[ヌクレオチド]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[wj:アデノシン三リン酸|ATP]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[wj:アデノシン二リン酸|ADP]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン三リン酸|UTP]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン二リン酸|UDP]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[wj:ウリジン二リン酸グルコース|UDPグルコース</del>]]</div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|| [[Gタンパク質共役型受容体]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|| [[Gタンパク質共役型受容体]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32527&oldid=prev
WikiSysop: /* P2Y14受容体 */
2015-11-26T00:07:29Z
<p><span dir="auto"><span class="autocomment">P2Y14受容体</span></span></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="ja">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月26日 (木) 09:07時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l69">69行目:</td>
<td colspan="2" class="diff-lineno">69行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||Gq/<sub>11</sub> || UTP=ATP||||[[2-thioUTP]]<br>[[PSB1114]]<br>[[Ap4A]]<br>[[UTPγS]]<br>[[MRS2768]]||[[AR-C118925XX]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || <del style="font-weight: bold; text-decoration: none;">UTPe</del>>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||Gi and Gq/<sub>11</sub> || <ins style="font-weight: bold; text-decoration: none;">UTP</ins>>ATP||||[[MRS4062]]<br>[[UTPγS]]||ATP (ヒト受容体)</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub> || UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[MRS295]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||Gq/<sub>11</sub> || UDP>>UTP>ATP||[[Rp-5-OMe-UDPαB]]||[[MRS295]]<br>[[MRS2693]]<br>[[3-フェナシル-UDP]]||[[MRS2578]]</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l79">79行目:</td>
<td colspan="2" class="diff-lineno">79行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||MRS2211</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| Gi || ADP>>ATP||||||MRS2211</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/gene/show/80135 80135]|| Gi || UDP ≥ UDP-<del style="font-weight: bold; text-decoration: none;">glucose</del>||MRS2690||||PPTN</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/gene/show/80135 80135]|| Gi || UDP ≥ UDP-<ins style="font-weight: bold; text-decoration: none;">グルコース</ins>||MRS2690||||PPTN</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td></tr>
</table>
WikiSysop
https://bsd.neuroinf.jp/w/index.php?title=P2Y%E5%8F%97%E5%AE%B9%E4%BD%93&diff=32526&oldid=prev
WikiSysop: /* P2Y14受容体 */
2015-11-26T00:06:13Z
<p><span dir="auto"><span class="autocomment">P2Y14受容体</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← 古い版</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">2015年11月26日 (木) 09:06時点における版</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l65">65行目:</td>
<td colspan="2" class="diff-lineno">65行目:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト!!</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>!受容体!!遺伝子!!Allen Brain Atlas!!細胞内情報伝達機構!!内在性アゴニスト!!アゴニスト!!選択的アゴニスト!!アンタゴニスト!!</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY1|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/11 || ADP>ATP||ADPβS<br>2MeSADP||MRS2365<br>2-Cl-ADP (α-BH3)||MRS2500<br>BMS compound 16<br>MRS2279<br>MRS2179<br>2‐2'‐ピリジルイサトゲントシラート</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY1|P2RY<sub>1</sub>]] || {{Gene|P2RY1}} || [http://mouse.brain-map.org/experiment/show/69863246 69863246]||Gq/<ins style="font-weight: bold; text-decoration: none;"><sub></ins>11<ins style="font-weight: bold; text-decoration: none;"></sub> </ins>|| ADP>ATP||<ins style="font-weight: bold; text-decoration: none;">[[</ins>ADPβS<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>2MeSADP<ins style="font-weight: bold; text-decoration: none;">]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2365<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>2-Cl-ADP<ins style="font-weight: bold; text-decoration: none;">]] </ins>(<ins style="font-weight: bold; text-decoration: none;">[[</ins>α-BH3<ins style="font-weight: bold; text-decoration: none;">]]</ins>)||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2500<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>BMS compound 16<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2279<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2179<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>2‐2'‐ピリジルイサトゲントシラート<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||<del style="font-weight: bold; text-decoration: none;">G</del><sub><del style="font-weight: bold; text-decoration: none;">q/</del>11</sub> || UTP=ATP||||2-thioUTP<br>PSB1114<br>Ap4A<br>UTPγS<br>MRS2768||AR-C118925XX</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY2|P2RY<sub>2</sub>]] || {{Gene|P2RY2}} || [http://mouse.brain-map.org/gene/show/18209 18209]||<ins style="font-weight: bold; text-decoration: none;">Gq/</ins><sub>11</sub> || UTP=ATP||||<ins style="font-weight: bold; text-decoration: none;">[[</ins>2-thioUTP<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>PSB1114<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>Ap4A<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>UTPγS<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2768<ins style="font-weight: bold; text-decoration: none;">]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[</ins>AR-C118925XX<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||<del style="font-weight: bold; text-decoration: none;">G<sub>i<</del>/<del style="font-weight: bold; text-decoration: none;">sub> and G</del><sub><del style="font-weight: bold; text-decoration: none;">q/</del>11</sub> || UTPe>ATP||||MRS4062<br>UTPγS||ATP (ヒト受容体)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY4|P2RY<sub>4</sub>]] || {{Gene|P2RY4}} || [http://mouse.brain-map.org/experiment/show/69258286 69258286]||<ins style="font-weight: bold; text-decoration: none;">Gi and Gq</ins>/<sub>11</sub> || UTPe>ATP||||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS4062<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>UTPγS<ins style="font-weight: bold; text-decoration: none;">]]</ins>||ATP (ヒト受容体)</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||<del style="font-weight: bold; text-decoration: none;">G</del><sub><del style="font-weight: bold; text-decoration: none;">q/</del>11</sub> || UDP>>UTP>ATP||Rp-5-OMe-UDPαB||<del style="font-weight: bold; text-decoration: none;">MRS295MRS2693</del><br>3-<del style="font-weight: bold; text-decoration: none;">phenacyl</del>-<del style="font-weight: bold; text-decoration: none;">UDP7</del>||MRS2578</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY6|P2RY<sub>6</sub>]] || {{Gene|P2RY6}} || [http://mouse.brain-map.org/experiment/show/100144178 100144178]||<ins style="font-weight: bold; text-decoration: none;">Gq/</ins><sub>11</sub> || UDP>>UTP>ATP||<ins style="font-weight: bold; text-decoration: none;">[[</ins>Rp-5-OMe-UDPαB<ins style="font-weight: bold; text-decoration: none;">]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[MRS295]]<br>[[MRS2693]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>3-<ins style="font-weight: bold; text-decoration: none;">フェナシル</ins>-<ins style="font-weight: bold; text-decoration: none;">UDP]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[</ins>MRS2578<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY11|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| <del style="font-weight: bold; text-decoration: none;">G<sub>s<</del>/<del style="font-weight: bold; text-decoration: none;">sub> and G</del><sub><del style="font-weight: bold; text-decoration: none;">q/</del>11</sub> || ATP>UTP||AR-C67085<br>NF546<br>NAADP<br>NAD||NF340||NF157</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY11|P2RY<sub>11</sub>]] || {{Gene|P2RY11}} |||| <ins style="font-weight: bold; text-decoration: none;">Gs and Gq</ins>/<sub>11</sub> || ATP>UTP||<ins style="font-weight: bold; text-decoration: none;">[[</ins>AR-C67085<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>NF546<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>NAADP<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>NAD<ins style="font-weight: bold; text-decoration: none;">]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[</ins>NF340<ins style="font-weight: bold; text-decoration: none;">]]</ins>||<ins style="font-weight: bold; text-decoration: none;">[[</ins>NF157<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY12|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| <del style="font-weight: bold; text-decoration: none;">G<sub>i</sub> </del> || ADP||2MeSADP||||PSB-0739<br>AZD1283<br>チカグレロル<br>ARL66096</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY12|P2RY<sub>12</sub>]] || {{Gene|P2RY12}} ||[http://mouse.brain-map.org/experiment/show/1907 1907]|| <ins style="font-weight: bold; text-decoration: none;">Gi </ins> || ADP||<ins style="font-weight: bold; text-decoration: none;">[[</ins>2MeSADP<ins style="font-weight: bold; text-decoration: none;">]]</ins>||||<ins style="font-weight: bold; text-decoration: none;">[[</ins>PSB-0739<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>AZD1283<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>チカグレロル<ins style="font-weight: bold; text-decoration: none;">]]</ins><br><ins style="font-weight: bold; text-decoration: none;">[[</ins>ARL66096<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| <del style="font-weight: bold; text-decoration: none;">G<sub>i</sub> </del> || ADP>>ATP||||||MRS2211</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY13|P2RY<sub>13</sub>]] || {{Gene|P2RY13}} ||[http://mouse.brain-map.org/experiment/show/69258280 69258280]|| <ins style="font-weight: bold; text-decoration: none;">Gi </ins> || ADP>>ATP||||||MRS2211</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> |- </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/gene/show/80135 80135]|| <del style="font-weight: bold; text-decoration: none;">G<sub>i</sub> </del> || UDP ≥ UDP-glucose||MRS2690||||PPTN</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> | [[P2RY14|P2RY<sub>14</sub>]] || {{Gene|P2RY14}} ||[http://mouse.brain-map.org/gene/show/80135 80135]|| <ins style="font-weight: bold; text-decoration: none;">Gi </ins> || UDP ≥ UDP-glucose||MRS2690||||PPTN</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>編集部にて[[w:P2Y purinergic receptor|Wikipedia]]、[http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52 Guide to Pharmacology P2Y受容体のページ]より[[翻訳]]、改変。</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== 参考文献 ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== 参考文献 ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td></tr>
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