テンプレート
:
PBB/22871
提供:脳科学辞典
<
テンプレート:PBB
2013年7月9日 (火) 16:37時点における
Tfuruya
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投稿記録
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による版
(ページの作成:「{{GNF_Protein_box | Name = Neuroligin 1 | image = | image_source = | PDB = | HGNCid = 14291 | MGIid = 2179435 | Symbol = NLGN1 | AltSymbols =; NL1 | IUPHAR = ...」)
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Neuroligin 1
Identifiers
Symbols
NLGN1
; NL1
External IDs
OMIM
:
600568
MGI
:
2179435
HomoloGene
:
56690
GeneCards
:
NLGN1 Gene
Gene Ontology
Molecular function
•
carboxylesterase activity
•
receptor activity
•
neurexin family protein binding
•
protein dimerization activity
•
cell adhesion molecule binding
Cellular component
•
integral to plasma membrane
•
cell surface
•
postsynaptic density
•
N-methyl-D-aspartate selective glutamate receptor complex
•
cell junction
•
dendrite
•
filopodium tip
•
synapse
•
postsynaptic membrane
Biological process
•
regulation of respiratory gaseous exchange by neurological system process
•
protein targeting
•
heterophilic cell-cell adhesion
•
neuron cell-cell adhesion
•
nervous system development
•
synapse assembly
•
positive regulation of intracellular protein kinase cascade
•
synaptic vesicle targeting
•
calcium-dependent cell-cell adhesion
•
neuronal signal transduction
•
positive regulation of synaptic transmission, GABAergic
•
establishment of protein localization
•
regulation of neuron differentiation
•
cytoskeletal matrix organization at active zone
•
protein homooligomerization
•
protein heterotetramerization
•
positive regulation of filopodium assembly
•
positive regulation of synapse assembly
•
positive regulation of synaptic transmission, glutamatergic
•
positive regulation of dendritic spine development
•
terminal button organization
•
synaptic vesicle clustering
•
postsynaptic membrane assembly
•
presynaptic membrane assembly
•
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering
•
N-methyl-D-aspartate receptor clustering
•
neurexin clustering
•
postsynaptic density protein 95 clustering
•
receptor localization to synapse
•
positive regulation of ruffle assembly
•
positive regulation of synaptic vesicle endocytosis
•
positive regulation of synaptic vesicle exocytosis
•
regulation of N-methyl-D-aspartate selective glutamate receptor activity
•
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
•
positive regulation of excitatory postsynaptic membrane potential
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
22871
192167
Ensembl
ENSG00000169760
ENSMUSG00000063887
UniProt
Q8N2Q7
Q99K10
RefSeq (mRNA)
NM_014932
NM_001163387
RefSeq (protein)
NP_055747
NP_001156859
Location (UCSC)
Chr 3:
173.11 – 174 Mb
Chr 3:
25.43 – 26.13 Mb
PubMed
search
[1]
[2]
v
t
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カテゴリ
:
Human proteins
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