テンプレート:PBB/27185

Disrupted in schizophrenia 1
Identifiers
Symbols	DISC1; C1orf136; SCZD9
External IDs	OMIM: 605210 MGI: 2447658 HomoloGene: 10257 GeneCards: DISC1 Gene
Gene Ontology Molecular function • protein binding Cellular component • mitochondrion • centrosome • microtubule • plasma membrane • postsynaptic density • cell junction • postsynaptic membrane Biological process • microtubule cytoskeleton organization • neuron migration • positive regulation of neuroblast proliferation • regulation of neuron projection development • cerebral cortex radially oriented cell migration • cell proliferation in forebrain • positive regulation of Wnt receptor signaling pathway • TOR signaling cascade • mitochondrial calcium ion homeostasis • canonical Wnt receptor signaling pathway • regulation of synapse maturation • positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27185	244667
Ensembl	ENSG00000162946	ENSMUSG00000043051
UniProt	Q9NRI5	Q811T9
RefSeq (mRNA)	NM_001012957	NM_170596
RefSeq (protein)	NP_001012975	NP_777278
Location (UCSC)	Chr 1: 231.76 – 232.18 Mb	Chr 8: 125.05 – 125.26 Mb
PubMed search	[1]	[2]