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58行目: |
58行目: |
| === 機能的分類(脳神経系における主要機能別分類) === | | === 機能的分類(脳神経系における主要機能別分類) === |
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| ''' ・'''''<b>Promotion of neuronal differentiation</b>'' <br> Ascl1 (Mash1), Atoh1 (Math1), [[Ebf1]], [[Ebf2]], [[Ebf3]], [[Ebf4]], [[Hand1]], [[Hand2]], [[Hes6]], [[Neurod1]] (Neurod/Beta2), [[Neurod2]] (Ndrf),
| | *ニューロンへの分化促進 '''<br> Ascl1 (Mash1), Atoh1 (Math1), [[Ebf1]], [[Ebf2]], [[Ebf3]], [[Ebf4]], [[Hand1]], [[Hand2]], [[Hes6]], [[Neurod1]] (Neurod/Beta2), [[Neurod2]] (Ndrf), Neurod4 (Math3), [[Neurod6]] (Math2), [[Neurog1]] (Ngn1), [[Neurog2]] (Ngn2), [[Ptf1a]], [[Sim1]]''' |
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| Neurod4 (Math3), [[Neurod6]] (Math2), [[Neurog1]] (Ngn1), [[Neurog2]] (Ngn2), [[Ptf1a]], [[Sim1]] | | *ニューロンへの分化抑制 <br> Hes1, Hes3, Hes5, [[Hey1]], [[Hey2]], [[HeyL]] ([[Hey3]]) |
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| ''''' '''''<b>・</b>'''''Inhibition of neuronal differentiation''''' <br> Hes1, Hes3, Hes5, [[Hey1]], [[Hey2]], [[HeyL]] ([[Hey3]])
| | *グリア分化<br> [[Olig1]], [[Olig2]], [[Olig3]], [[Tal1]] (Scl) |
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| ''''' '''''<b>・</b>'''''Glial differentiation'''''<br> [[Olig1]], [[Olig2]], [[Olig3]], [[Tal1]] (Scl)
| | *小脳発達<br> [[Atoh1]] (Math1), [[Nhlh1]] (Nscl1), [[Nhlh2]] (Nscl2), [[Ptf1a]] |
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| ''''' '''''<b>・</b>'''''Cerebellar development'''''<br> [[Atoh1]] (Math1), [[Nhlh1]] (Nscl1), [[Nhlh2]] (Nscl2), [[Ptf1a]]
| | *自律神経系ニューロン新生<br> Ascl1 (Mash1), Hand1, Hand2 |
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| ''''' '''''<b>・</b>'''''Autonomic neurogenesis'''''<br> Ascl1 (Mash1), Hand1, Hand2
| | *細胞周期<br> Myc (c-Myc), [[Mycn]] (N-Myc) |
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| ''''' '''''<b>・</b>'''''Cell cycle'''''<br> Myc (c-Myc), [[Mycn]] (N-Myc)
| | *概日リズム<br> [[Ahr]], [[Ahrr]], [[Arntl]] (Bmal1), [[Clock]], [[Bhlhe40]] (Dec1), [[Bhlhe41]] (Dec2), [[Npas]], [[Per]], [[Sim]] |
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| ''''' '''''<b>・</b>'''''Circadian rhythm'''''<br> [[Ahr]], [[Ahrr]], [[Arntl]] (Bmal1), [[Clock]], [[Bhlhe40]] (Dec1), [[Bhlhe41]] (Dec2), [[Npas]], [[Per]], [[Sim]]
| | *コファクター<br> [[Tcf3]] (E12/E47), [[Tcf4]] (E2-2)<br> |
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| ''''' '''''<b>・</b>'''''Cofactor'''''<br> [[Tcf3]] (E12/E47), [[Tcf4]] (E2-2)<br>
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| *The HUGO Gene Nomenclature Committee (HGNC) provides a list of genes in the bHLH family (http://www.genenames.org/genefamily/bhlh.php)
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| | HUGO遺伝子命名法委員会により、bHLHファミリーの[http://www.genenames.org/genefamily/bhlh.php 命名]が整理されている。 |
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| == 機能 == | | == 機能 == |