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| ==Brodmann areas for human & non-human primates== | | {| class="wikitable" |
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| | ! 受容体 |
| | ! アゴニスト選択性 |
| | ! 主な作用 |
| | ! 細胞内シグナル |
| | ! [[wikipedia:Adrenergic agonist|アゴニスト]] |
| | ! [[wikipedia:Adrenergic antagonist|アンタゴニスト]] |
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| | | [[wikipedia:Α1 adrenergic receptor|α<sub>1</sub>]]:<br>[[wikipedia:Alpha-1A adrenergic receptor|A]], [[wikipedia:Alpha-1B adrenergic receptor|B]], [[wikipedia:Alpha-1D adrenergic receptor|D]]<sup>†</sup> |
| | | style="white-space:nowrap" | [[ノルアドレナリン]] > [[アドレナリン]] >> [[イソプレナリン]] |
| | | [[平滑筋]]収縮 |
| | | [[Gq alpha subunit|G<sub>q</sub>]]: [[ホスホリパーゼ C]] (PLC) 活性化により[[イノシトール3リン酸]]と[[ジアシルグリセロール]]、細胞内[[カルシウム]]の上昇 |
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| | ''([[wikipedia:Alpha-adrenergic agonist|α<sub>1</sub>アゴニスト]])'' |
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| | *[[ノルアドレナリン]] |
| | *[[フェニレフリン]] |
| | *[[メトキサミン]] |
| | *[[シラゾリン]] |
| | *[[キシロメタゾリン]] |
| | *[[ミドドリン]] |
| | *[[メタラミノール]] |
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| * [[Brodmann areas 3, 1 and 2|ブロードマン3、1、2野 - 一次体性感覚野]] (frequently referred to as Areas 3, 1, 2 by convention)
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| * [[Brodmann area 4|ブロードマン4野 – 一次運動野]]
| | ''([[wikipedia:Alpha-1 blocker|α<sub>1</sub>アンタゴニスト]])'' |
| * [[Brodmann area 5|ブロードマン5野 – 体性感覚連合野]]
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| * [[Brodmann area 6|ブロードマン6野]] - [[前運動野]] 、補足運動野
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| * [[Brodmann area 7|ブロードマン7野 -体性感覚連合野]]]
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| * [[Brodmann area 8|ブロードマン8野]] - [[前頭眼野]]
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| * [[Brodmann area 9|ブロードマン9野]] - [[前頭前野背外側部]]
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| * [[Brodmann area 10|ブロードマン10野]] - [[前頭極]]
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| * [[Brodmann area 11|ブロードマン11野]] - [[眼窩前頭野]]
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| * [[Brodmann area 12|ブロードマン12野]] - [[眼窩前頭野]]
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| * [[Brodmann area 13|ブロードマン13野]] and [[Brodmann area 14|ブロードマン14野]]<sup>*</sup> - [[島皮質]]
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| * [[Brodmann area 15|ブロードマン15野]]<sup>*</sup> - Anterior Temporal Lobe
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| * [[Brodmann area 17|ブロードマン17野]] - [[Visual_cortex#V1|一次視覚野 (V1)]]
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| * [[Brodmann area 18|ブロードマン18野]] - [[Visual_cortex#V2|二次視覚野(V2)]]]
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| * [[Brodmann area 19|ブロードマン19野]] - [[Visual_cortex#V3|視覚連合野(V3)]]
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| * [[Brodmann area 20|ブロードマン20野]] - [[下側頭回]]
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| * [[Brodmann area 21|ブロードマン21野]] - [[中側頭回]]
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| * [[Brodmann area 22|ブロードマン22野]] - [[上側頭回]]
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| * [[Brodmann area 23|ブロードマン23野]] - 腹側[[後帯状皮質]]
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| * [[Brodmann area 24|ブロードマン24野]] - 腹側[[前帯状皮質]]
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| * [[Brodmann area 25|ブロードマン25野]] – [[膝下野]]
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| * [[Brodmann area 26|ブロードマン26野]] - [[Ectosplenial_area_26|Ectosplenial]] portion of the retrosplenial region of the cerebral cortex
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| * [[Brodmann area 27|ブロードマン27野]] - [[梨状葉皮質]]
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| * [[Brodmann area 28|ブロードマン28野]] - [[後嗅内皮質]]
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| * [[Brodmann area 29|ブロードマン29野]] - [[脳梁膨大後部帯状皮質]]
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| * [[Brodmann area 30|ブロードマン30野]] - [[帯状皮質]]の一部
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| * [[Brodmann area 31|ブロードマン31野]] - [[背側後帯状皮質]]
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| * [[Brodmann area 32|ブロードマン32野]] - [[背側前帯状皮質]]
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| * [[Brodmann area 33|ブロードマン33野]] - [[前帯状皮質]]の一部
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| * [[Brodmann area 34|ブロードマン34野]] - [[前嗅内皮質]] (on the [[海馬傍回]])
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| * [[Brodmann area 35|ブロードマン35野]] - [[嗅周囲皮質]] (on the [[海馬傍回]])
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| * [[Brodmann area 36|ブロードマン36野]] - [[海馬傍回皮質]] (on the [[海馬傍回皮質]])
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| * [[Brodmann area 37|ブロードマン37野]] - [[紡錘状回]]
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| * [[Brodmann area 38|ブロードマン38野]] - [[側頭極]]
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| * [[Brodmann area 39|ブロードマン39野]] - [[角回]]
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| * [[Brodmann area 40|ブロードマン40野]] - [[縁上回]]
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| * [[Brodmann area 41 & 42|ブロードマン41、42野 - 一次聴覚野]]
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| * [[Brodmann area 43|ブロードマン43野]] - Primary gustatory cortex
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| * [[Brodmann area 44|ブロードマン44野]] - [[下前頭回]][[弁蓋部]]
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| * [[Brodmann area 45|ブロードマン45野]] - [[下前頭回]] [[三角部]]
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| * [[Brodmann area 46|ブロードマン46野]] - [[前頭前野背外側部]]
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| * [[Brodmann area 47|ブロードマン47野]] - [[下前頭前野]]
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| * [[Brodmann area 48|ブロードマン48野]] - [[Brodmann_area_48|Retrosubicular area]] (a small part of the medial surface of the temporal lobe)
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| * [[Brodmann area 49|ブロードマン49野]] - [[Parasubiculum]] area in a rodent
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| * [[Brodmann area 52|ブロードマン52野]] - [[Parainsular_area_52|Parainsular]] area (at the junction of the temporal lobe and the [[Insular cortex|insula]])
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| (*) Area only found in non-human [[primate]]s.
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| Some of the original Brodmann areas have been subdivided further, e.g., "23a" and "23b".<ref>{{Cite journal
| | *[[アルフゾシン]] |
| | author = Brent A. Vogt, [[Deepak Pandya|Deepak N. Pandya]], Douglas L. Rosene
| | *[[ドキサゾシン]] |
| | title = Cingulate cortex of the rhesus monkey: I. Cytoarchitecture and thalamic afferents
| | *[[ヘノキシベンザミン]] |
| | journal = The Journal of Comparative Neurology
| | *[[フェントラミン]] |
| | volume = 262
| | *[[プラゾシン]] |
| | issue = 2
| | *[[タムスロシン]] |
| | pages = 256–270
| | *[[テラゾシン]] |
| | month = August
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| | year = 1987
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| | doi = 10.1002/cne.902620207
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| | pmid = 3624554
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| }}</ref>
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| === Clickable map: Lateral Surface ===
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| <imagemap>
| | | [[Α2 adrenergic receptor|α<sub>2</sub>]]:<br>[[Alpha-2A adrenergic receptor|A]], [[Alpha-2B adrenergic receptor|B]], [[Alpha-2C adrenergic receptor|C]] |
| Image:Gray726-Brodman.png|Image mapped [[Brodmann Areas]]. Clicking on an area in the picture causes the browser to load the appropriate article.|480px
| | | [[アドレナリン]] ≥ [[ノルアドレナリン]] >> [[イソプレナリン]] |
| rect 509 186 596 236 [[Brodmann areas 3, 1 and 2|Areas 3, 1 & 2 - Primary Somatosensory Cortex]]
| | | 自己受容体活性化による神経伝達物質放出減少、[[心筋]]弛緩、 [[血小板]]活性化 |
| rect 474 122 524 172 [[Brodmann area 4|Area 4 - Primary Motor Cortex]]
| | | [[Gi alpha subunit|G<sub>i</sub>]]: [[アデニル酸シクラーゼ]]抑制, [[サイクリックAMP|cAMP]]減少 |
| rect 602 143 652 193 [[Brodmann area 5|Area 5 - Somatosensory Association Cortex]]
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| rect 378 162 428 212 [[Brodmann area 6|Area 6 - Premotor cortex and Supplementary Motor Cortex (Secondary Motor Cortex)(Supplementary motor area]]
| | ''([[wikipedia:Alpha-adrenergic agonist|α2アゴニスト]])'' |
| rect 692 178 742 228 [[Brodmann area 7|Area 7 - Somatosensory Association Cortex]]
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| rect 259 107 309 157 [[Brodmann area 8|Area 8 - Includes Frontal eye fields]]
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| rect 137 162 188 212 [[Brodmann area 9|Area 9- Dorsolateral prefrontal cortex]]
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| rect 31 330 81 380 [[Brodmann area 10|Area 10 - Anterior prefrontal cortex]]
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| rect 65 427 116 477 [[Brodmann area 11|Area 11 - Orbitofrontal area]]
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| rect 892 459 942 509 [[Brodmann area 17|Area 17 - Primary visual cortex (V1)]]
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| rect 834 427 885 477 [[Brodmann area 18|Area 18 - Secondary visual cortex (V2)]]
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| rect 770 385 821 435 [[Brodmann area 19|Area 19 - Associative visual cortex (V3)]]
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| rect 427 554 477 604 [[Brodmann area 20|Area 20 - Inferior temporal gyrus]]
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| rect 474 491 524 541 [[Brodmann area 21|Area 21 - Middle temporal gyrus]]
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| rect 635 417 686 467 [[Brodmann area 22|Area 22 - Superior temporal gyrus]]
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| rect 673 484 723 534 [[Brodmann area 37|Area 37 - Fusiform gyrus]]
| | *[[デクスメデトミジン]] |
| rect 250 505 301 555 [[Brodmann area 38|Area 38 - Temporopolar area]]
| | *[[メデトミジン]] |
| rect 706 307 757 357 [[Brodmann area 39|Area 39 - Angular gyrus]]
| | *[[ロミフィジン]] |
| rect 571 315 622 365 [[Brodmann area 40|Area 40 - Supramarginal gyrus]]
| | *[[クロニジン]] |
| rect 536 394 587 444 [[Brodmann area 41 & 42|Area 41- Primary and Auditory Association Cortex]]
| | *[[ブリモニジン]] |
| rect 589 411 634 461 [[Brodmann area 41 & 42|Area 42 - Primary and Auditory Association Cortex]]
| | *[[デトミジン]] |
| rect 416 368 467 418 [[Brodmann area 43|Area 43 - Primary gustatory cortex]]
| | *[[ロフェキシジン]] |
| rect 282 353 333 403 [[Brodmann area 44|Area 44 - pars opercularis, part of Broca's area]]
| | *[[キシラジン]] |
| rect 219 378 270 428 [[Brodmann area 45|Area 45 - pars triangularis, Broca's area]]
| | *[[チザニジン]] |
| rect 144 257 195 307 [[Brodmann area 46|Area 46 - Dorsolateral prefrontal cortex]]
| | *[[グアンファシン]] |
| rect 145 410 196 460 [[Brodmann area 47|Area 47 - Inferior prefontal gyrus]]
| | *[[アミトラズ]] |
| rect 958 718 960 720 [http://www.image-maps.com/index.php?aff=mapped_users_4201105031226273 Image Map]
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| desc bottom-left
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| </imagemap>
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| === Clickable map: Medial Surface ===
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| | ''([[wikipedia:Α2 blocker|α2アンタゴニスト]])'' |
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| <imagemap>
| | *[[フェントラミン]] |
| Image:Gray727-Brodman.png|Image mapped [[Brodmann Areas]]. Clicking on an area in the picture causes the browser to load the appropriate article.|480px
| | *[[ヨヒンビン]] |
| rect 509 186 596 236 [[Brodmann areas 3, 1 and 2|Areas 3, 1 & 2 - Primary Somatosensory Cortex]]
| | *[[イダゾキサン]] |
| rect 442 99 492 149 [[brodmann area 4|area 4 - primary motor cortex]]
| | *[[アチパメゾール]] |
| rect 538 162 588 212 [[Brodmann area 5|Area 5 - Somatosensory Association Cortex]]
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| rect 306 122 356 172 [[Brodmann area 6|Area 6 - Premotor cortex and Supplementary Motor Cortex (Secondary Motor Cortex)(Supplementary motor area]]
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| rect 714 155 764 205 [[Brodmann area 7|Area 7 - Somatosensory Association Cortex]]
| | | [[Beta-1 adrenergic receptor|β<sub>1</sub>]] |
| rect 193 155 243 205 [[Brodmann area 8|Area 8 - Includes Frontal eye fields]]
| | | [[イソプレナリン]] > [[アドレナリン]] = [[ノルアドレナリン]] |
| rect 106 211 156 261 [[Brodmann area 9|Area 9- Dorsolateral prefrontal cortex]]
| | | [[心筋]]収縮 |
| rect 35 323 85 373 [[Brodmann area 10|Area 10 - Anterior prefrontal cortex]]
| | | [[Gs alpha subunit|G<sub>s</sub>]]: [[アデニル酸シクラーゼ]]活性化、[[サイクリックAMP|cAMP]]上昇 |
| rect 74 441 124 491 [[Brodmann area 11|Area 11 - Orbitofrontal area]]
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| rect 162 404 212 454 [[Brodmann area 12|Area 12 -Orbitofrontal area]]
| | ''([[wikipedia:Beta1-adrenergic agonist|β<sub>1</sub>アゴニスト]])'' |
| rect 819 378 869 428 [[Brodmann area 17|Area 17 - Primary visual cortex (V1)]]
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| rect 761 428 811 478 [[Brodmann area 18|Area 18 - Secondary visual cortex (V2)]]
| | *[[ドブタミン]] |
| rect 697 467 747 517 [[Brodmann area 19|Area 19 - Associative visual cortex (V3)]]
| | *[[イソプレナリン]] |
| rect 810 233 860 283 [[Brodmann area 19|Area 19 - Associative visual cortex (V3)]]
| | *[[ノルアドレナリン]] |
| rect 860 308 910 358 [[Brodmann area 18|Area 18 - Secondary visual cortex (V2)]]
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| rect 563 289 613 339 [[Brodmann area 23|Area 23 - Ventral Posterior cingulate cortex]]
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| rect 314 210 364 260 [[Brodmann area 24|Area 24 - Ventral Anterior cingulate cortex]]
| | ''([[wikipedia:ja:交感神経β受容体遮断薬|β<sub>1</sub>アンタゴニスト]])'' |
| rect 227 434 277 484 [[Brodmann area 25|Area 25 - Subgenual cortex (part of the Ventromedial prefontal cortex)]]
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| rect 512 355 562 405 [[Brodmann area 26|Area 26 - Ectosplenial portion of the retrosplenial region of the cerebral cortex]]
| | *[[メトプロロール]] |
| rect 377 448 427 498 [[Brodmann area 27|Area 27 - Piriform cortex]]
| | *[[アテノロール]] |
| rect 314 489 364 539 [[Brodmann area 28|Area 28 - Posterior Entorhinal Cortex]]
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| rect 571 371 621 421 [[Brodmann area 29|Area 29 - Retrosplenial cingulate cortex]]
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| rect 532 419 582 469 [[Brodmann area 30|Area 30 - Part of cingulate cortex]]
| | | [[Beta-2 adrenergic receptor|β<sub>2</sub>]] |
| rect 632 264 682 314 [[Brodmann area 31|Area 31 - Dorsal Posterior cingulate cortex]]
| | | [[イソプレナリン]] > [[アドレナリン]] >> [[ノルアドレナリン]] |
| rect 138 330 188 380 [[Brodmann area 32|Area 32 - Dorsal anterior cingulate cortex]]
| | | [[平滑筋]]弛緩 |
| rect 234 290 284 340 [[Brodmann area 33|Area 33 - Part of anterior cingulate cortex]]
| | | [[Gs alpha subunit|G<sub>s</sub>]]: [[アデニル酸シクラーゼ]]活性化、[[サイクリックAMP|cAMP]]上昇 ([[Gi alpha subunit|Gi]]と共役することもある) |
| rect 305 435 355 485 [[Brodmann area 34|Area 34 - Anterior Entorhinal Cortex (on the Parahippocampal gyrus)]]
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| rect 448 450 498 500 [[Brodmann area 35|Area 35 - Perirhinal cortex (on the Parahippocampal gyrus)]]
| | ''([[wikipedia:ja:交感神経β2受容体作動薬|β<sub>2</sub>アゴニスト]])'' |
| rect 448 507 498 557 [[Brodmann area 20|Area 20 - Inferior temporal gyrus]]
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| rect 585 482 635 532 [[Brodmann area 37|Area 37 - Fusiform gyrus]]
| | *[[サルブタモール]] |
| rect 559 100 648 150 [[Brodmann areas 3, 1 and 2|Areas 3, 1 & 2 - Primary Somatosensory Cortex]]
| | *[[ビトルテロール]] |
| rect 265 532 318 582 [[Brodmann area 38|Area 38 - Temporopolar area]]
| | *[[ホルモテロール]] |
| rect 958 718 960 720 [http://www.image-maps.com/index.php?aff=mapped_users_1201105031640502 Image Map]
| | *[[イソプレナリン]] |
| desc bottom-left
| | *[[アイロミール]] |
| </imagemap> | | *[[メタプロテレノール]] |
| <references/> | | *[[サルメテロール]] |
| | *[[テルブタリン]] |
| | *[[リトドリン]] |
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| | | |
| | ''([[wikipedia:ja:交感神経β受容体遮断薬|β<sub>2</sub>アンタゴニスト]])'' |
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| | *[[ブトキサミン]] |
| | *[[プロプラノロール]] |
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| | |- |
| | | [[Beta-3 adrenergic receptor|β<sub>3</sub>]] |
| | | [[イソプレナリン]] = [[ノルアドレナリン]] > [[アドレナリン]] |
| | | [[脂肪]]代謝亢進、[[膀胱排尿筋]]弛緩 |
| | | [[Gs alpha subunit|G<sub>s</sub>]]: [[アデニル酸シクラーゼ]]活性化、[[サイクリックAMP|cAMP]]上昇 |
| | | |
| | *L-796568 |
| | *[[アミベグロン]] |
| | *[[ソラベグロン]] |
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| | | |
| | *[[SR 59230A]] |
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| | |} |
| | |
| | Wikipedia項目[[wikipedia:Adrenergic Receptor|Adrenergic Receptor]]から翻訳、加筆の上転載。 |
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| | <sup>†</sup>α<sub>1C</sub>受容体と呼ばれる物は、存在しない。 |