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…Mytatrienediol]] (16α-methyl-16β-epiestriol 3-methyl ether) is a synthetic derivative of 16β-epiestriol that was never marketed.<ref name="Elks2014" /> [[Estrio …, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy? | journal = Postgraduate Medicine | volume

…, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy? | journal = Postgraduate Medicine | volume …hinylestradiol]], a [[synthetic compound|synthetic]] [[chemical derivative|derivative]] of estradiol, was synthesized from estradiol by Inhoffen and Hohlweg in…